SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_C_ZPCC1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	3f3b	PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH (Bacillus subtilis)	5 / 12	PHE A 52 ILE A 13 TYR A 51 HIS A 9 VAL A 48	None None None PO4 A 127 (-3.5A) None	1.29A	4a97B-3f3bA: undetectable 4a97C-3f3bA: undetectable	4a97B-3f3bA: 18.84 4a97C-3f3bA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DMG_A_SAMA401_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493)	3f3b	PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH (Bacillus subtilis)	5 / 12	TYR A 95 TYR A 14 ASP A 12 GLU A 91 ASP A 115	None None None PO4 A 127 (-3.8A) PO4 A 128 ( 4.9A)	1.49A	4dmgA-3f3bA: undetectable	4dmgA-3f3bA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DMG_B_SAMB401_0 (PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493)	3f3b	PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH (Bacillus subtilis)	5 / 11	TYR A 95 TYR A 14 ASP A 12 GLU A 91 ASP A 115	None None None PO4 A 127 (-3.8A) PO4 A 128 ( 4.9A)	1.48A	4dmgB-3f3bA: undetectable	4dmgB-3f3bA: 14.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A97_C_ZPCC1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","3f3b","PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH","Bacillus subtilis",5,"PHE A  52;ILE A  13;TYR A  51;HIS A   9;VAL A  48","None;None;None;PO4 A 127 (-3.5A);None","1.29A","4a97B-3f3bA:undetectable;4a97C-3f3bA:undetectable","4a97B-3f3bA:18.84;4a97C-3f3bA:18.84"],["4DMG_A_SAMA401_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493","3f3b","PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH","Bacillus subtilis",5,"TYR A  95;TYR A  14;ASP A  12;GLU A  91;ASP A 115","None;None;None;PO4 A 127 (-3.8A);PO4 A 128 ( 4.9A)","1.49A","4dmgA-3f3bA:undetectable","4dmgA-3f3bA:14.50"],["4DMG_B_SAMB401_0","PUTATIVE UNCHARACTERIZED PROTEIN TTHA1493","3f3b","PHAGE-LIKE ELEMENT PBSX PROTEIN XKDH","Bacillus subtilis",5,"TYR A  95;TYR A  14;ASP A  12;GLU A  91;ASP A 115","None;None;None;PO4 A 127 (-3.8A);PO4 A 128 ( 4.9A)","1.48A","4dmgB-3f3bA:undetectable","4dmgB-3f3bA:14.50"]]