SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f3z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 1k2sA-3f3zA:
undetectable
1k2sB-3f3zA:
undetectable
1k2sA-3f3zA:
21.13
1k2sB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.38A 1k2sA-3f3zA:
undetectable
1k2sB-3f3zA:
undetectable
1k2sA-3f3zA:
21.13
1k2sB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 1k2uA-3f3zA:
undetectable
1k2uB-3f3zA:
undetectable
1k2uA-3f3zA:
21.13
1k2uB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 1m00A-3f3zA:
undetectable
1m00B-3f3zA:
undetectable
1m00A-3f3zA:
21.13
1m00B-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 5 ILE A 168
LEU A 167
VAL A 132
ALA A 276
DRK  A   1 ( 4.2A)
None
None
None
0.95A 1mz9C-3f3zA:
undetectable
1mz9C-3f3zA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 1nsiA-3f3zA:
undetectable
1nsiB-3f3zA:
undetectable
1nsiA-3f3zA:
20.85
1nsiB-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 1nsiA-3f3zA:
undetectable
1nsiB-3f3zA:
undetectable
1nsiA-3f3zA:
20.85
1nsiB-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 1nsiC-3f3zA:
undetectable
1nsiD-3f3zA:
undetectable
1nsiC-3f3zA:
20.85
1nsiD-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 1nsiC-3f3zA:
undetectable
1nsiD-3f3zA:
undetectable
1nsiC-3f3zA:
20.85
1nsiD-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 1om5A-3f3zA:
undetectable
1om5B-3f3zA:
undetectable
1om5A-3f3zA:
21.03
1om5B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.37A 1p6hA-3f3zA:
undetectable
1p6hB-3f3zA:
undetectable
1p6hA-3f3zA:
21.03
1p6hB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 1p6kA-3f3zA:
undetectable
1p6kB-3f3zA:
undetectable
1p6kA-3f3zA:
21.03
1p6kB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
3 / 3 ASP A 229
THR A 188
GLU A 152
None
0.75A 1pj7A-3f3zA:
undetectable
1pj7A-3f3zA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 10 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
0.97A 1pxxA-3f3zA:
undetectable
1pxxA-3f3zA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
0.96A 1pxxC-3f3zA:
undetectable
1pxxC-3f3zA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 5 ILE A 259
TRP A 248
LEU A 263
PRO A 223
None
1.24A 1s8fA-3f3zA:
undetectable
1s8fB-3f3zA:
undetectable
1s8fA-3f3zA:
19.46
1s8fB-3f3zA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ILE A  34
VAL A  42
ILE A  85
ASP A 169
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
None
None
0.74A 1uwhA-3f3zA:
14.7
1uwhA-3f3zA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ILE A  34
VAL A  42
ILE A  85
ASP A 169
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
None
None
0.74A 1uwhB-3f3zA:
8.7
1uwhB-3f3zA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 MET A 213
VAL A 216
LEU A 217
PHE A 120
None
0.75A 1x8vA-3f3zA:
undetectable
1x8vA-3f3zA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 9 VAL A  42
LYS A  57
LEU A  88
LEU A 100
LEU A 104
DRK  A   1 ( 4.9A)
DRK  A   1 (-4.1A)
None
None
DRK  A   1 (-4.4A)
0.54A 1xkkA-3f3zA:
22.2
1xkkA-3f3zA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 1zzqA-3f3zA:
undetectable
1zzqB-3f3zA:
undetectable
1zzqA-3f3zA:
21.13
1zzqB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 2g6hA-3f3zA:
undetectable
2g6hB-3f3zA:
undetectable
2g6hA-3f3zA:
21.13
2g6hB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 2g6mA-3f3zA:
undetectable
2g6mB-3f3zA:
undetectable
2g6mA-3f3zA:
21.13
2g6mB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 2g6mA-3f3zA:
undetectable
2g6mB-3f3zA:
undetectable
2g6mA-3f3zA:
21.13
2g6mB-3f3zA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.37A 2nsiA-3f3zA:
undetectable
2nsiB-3f3zA:
undetectable
2nsiA-3f3zA:
20.85
2nsiB-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 2nsiA-3f3zA:
undetectable
2nsiB-3f3zA:
undetectable
2nsiA-3f3zA:
20.85
2nsiB-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.35A 2nsiC-3f3zA:
undetectable
2nsiD-3f3zA:
undetectable
2nsiC-3f3zA:
20.85
2nsiD-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 2nsiC-3f3zA:
undetectable
2nsiD-3f3zA:
undetectable
2nsiC-3f3zA:
20.85
2nsiD-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
8 / 12 ILE A  34
VAL A  42
ALA A  55
ILE A  86
LEU A 104
GLY A 108
GLU A 109
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.6A)
0.82A 2y7jA-3f3zA:
30.1
2y7jA-3f3zA:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 10 ILE A  34
VAL A  42
ALA A  55
ILE A  86
LEU A 104
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
DRK  A   1 (-4.6A)
0.59A 2y7jB-3f3zA:
35.0
2y7jB-3f3zA:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 10 ILE A  34
VAL A  42
ALA A  55
ILE A  86
LEU A 104
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
DRK  A   1 (-4.6A)
0.60A 2y7jC-3f3zA:
30.4
2y7jC-3f3zA:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 10 ILE A  34
VAL A  42
ALA A  55
ILE A  86
LEU A 104
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
DRK  A   1 (-4.6A)
0.63A 2y7jD-3f3zA:
30.4
2y7jD-3f3zA:
27.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3b3mA-3f3zA:
undetectable
3b3mB-3f3zA:
undetectable
3b3mA-3f3zA:
21.03
3b3mB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3b3mA-3f3zA:
undetectable
3b3mB-3f3zA:
undetectable
3b3mA-3f3zA:
21.03
3b3mB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.38A 3b3pA-3f3zA:
undetectable
3b3pB-3f3zA:
undetectable
3b3pA-3f3zA:
21.03
3b3pB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3dqtA-3f3zA:
undetectable
3dqtB-3f3zA:
1.0
3dqtA-3f3zA:
20.52
3dqtB-3f3zA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 3e7gA-3f3zA:
undetectable
3e7gB-3f3zA:
undetectable
3e7gA-3f3zA:
20.80
3e7gB-3f3zA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 3e7gA-3f3zA:
undetectable
3e7gB-3f3zA:
undetectable
3e7gA-3f3zA:
20.80
3e7gB-3f3zA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3e7gC-3f3zA:
undetectable
3e7gD-3f3zA:
undetectable
3e7gC-3f3zA:
20.80
3e7gD-3f3zA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.28A 3e7gC-3f3zA:
undetectable
3e7gD-3f3zA:
undetectable
3e7gC-3f3zA:
20.80
3e7gD-3f3zA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
3 / 3 GLY A 239
PRO A 223
LEU A 263
None
0.49A 3hcpB-3f3zA:
undetectable
3hcpB-3f3zA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3hspA-3f3zA:
undetectable
3hspB-3f3zA:
undetectable
3hspA-3f3zA:
21.03
3hspB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3jt3A-3f3zA:
undetectable
3jt3B-3f3zA:
undetectable
3jt3A-3f3zA:
21.03
3jt3B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 3jt4A-3f3zA:
undetectable
3jt4B-3f3zA:
undetectable
3jt4A-3f3zA:
21.03
3jt4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 3jt4A-3f3zA:
undetectable
3jt4B-3f3zA:
undetectable
3jt4A-3f3zA:
21.03
3jt4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3jt6A-3f3zA:
undetectable
3jt6B-3f3zA:
undetectable
3jt6A-3f3zA:
21.03
3jt6B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 3jwvA-3f3zA:
undetectable
3jwvB-3f3zA:
undetectable
3jwvA-3f3zA:
20.61
3jwvB-3f3zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3jx0A-3f3zA:
undetectable
3jx0B-3f3zA:
undetectable
3jx0A-3f3zA:
21.03
3jx0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.37A 3jx0A-3f3zA:
undetectable
3jx0B-3f3zA:
undetectable
3jx0A-3f3zA:
21.03
3jx0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3jx1A-3f3zA:
undetectable
3jx1B-3f3zA:
undetectable
3jx1A-3f3zA:
21.03
3jx1B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 3jx1A-3f3zA:
undetectable
3jx1B-3f3zA:
undetectable
3jx1A-3f3zA:
21.03
3jx1B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 3jx5A-3f3zA:
undetectable
3jx5B-3f3zA:
undetectable
3jx5A-3f3zA:
21.03
3jx5B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 3jx6A-3f3zA:
undetectable
3jx6B-3f3zA:
undetectable
3jx6A-3f3zA:
21.03
3jx6B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 ALA A  55
LYS A  57
LEU A 100
LEU A 104
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
None
DRK  A   1 (-4.4A)
0.34A 3lfaA-3f3zA:
19.3
3lfaA-3f3zA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3n5pA-3f3zA:
0.0
3n5pB-3f3zA:
0.0
3n5pA-3f3zA:
21.12
3n5pB-3f3zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.25A 3n5yA-3f3zA:
undetectable
3n5yB-3f3zA:
undetectable
3n5yA-3f3zA:
21.03
3n5yB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 3n5yA-3f3zA:
undetectable
3n5yB-3f3zA:
undetectable
3n5yA-3f3zA:
21.03
3n5yB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3n5zA-3f3zA:
undetectable
3n5zB-3f3zA:
undetectable
3n5zA-3f3zA:
21.03
3n5zB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3n67A-3f3zA:
0.0
3n67B-3f3zA:
0.0
3n67A-3f3zA:
21.12
3n67B-3f3zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.35A 3nlmA-3f3zA:
undetectable
3nlmB-3f3zA:
undetectable
3nlmA-3f3zA:
21.03
3nlmB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3nlmA-3f3zA:
undetectable
3nlmB-3f3zA:
undetectable
3nlmA-3f3zA:
21.03
3nlmB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 3nloA-3f3zA:
undetectable
3nloB-3f3zA:
undetectable
3nloA-3f3zA:
20.61
3nloB-3f3zA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3nlpA-3f3zA:
undetectable
3nlpB-3f3zA:
undetectable
3nlpA-3f3zA:
21.03
3nlpB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 3nlvA-3f3zA:
undetectable
3nlvB-3f3zA:
undetectable
3nlvA-3f3zA:
21.03
3nlvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3nlwA-3f3zA:
undetectable
3nlwB-3f3zA:
undetectable
3nlwA-3f3zA:
21.03
3nlwB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3nlxA-3f3zA:
undetectable
3nlxB-3f3zA:
undetectable
3nlxA-3f3zA:
21.03
3nlxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3nlxA-3f3zA:
undetectable
3nlxB-3f3zA:
undetectable
3nlxA-3f3zA:
21.03
3nlxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 3nlyA-3f3zA:
undetectable
3nlyB-3f3zA:
undetectable
3nlyA-3f3zA:
21.03
3nlyB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 3nlzA-3f3zA:
undetectable
3nlzB-3f3zA:
undetectable
3nlzA-3f3zA:
21.03
3nlzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3nlzA-3f3zA:
undetectable
3nlzB-3f3zA:
undetectable
3nlzA-3f3zA:
21.03
3nlzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3nm0A-3f3zA:
undetectable
3nm0B-3f3zA:
undetectable
3nm0A-3f3zA:
21.03
3nm0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3nm0A-3f3zA:
undetectable
3nm0B-3f3zA:
undetectable
3nm0A-3f3zA:
21.03
3nm0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3nnzA-3f3zA:
undetectable
3nnzB-3f3zA:
undetectable
3nnzA-3f3zA:
21.03
3nnzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OG7_A_032A1_1
(AKAP9-BRAF FUSION
PROTEIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 12 ILE A  34
VAL A  42
ALA A  55
LYS A  57
CYH A 105
PHE A 170
DRK  A   1 (-4.2A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 (-4.1A)
None
1.02A 3og7A-3f3zA:
18.2
3og7A-3f3zA:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 3pneA-3f3zA:
undetectable
3pneB-3f3zA:
undetectable
3pneA-3f3zA:
21.03
3pneB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 3pneA-3f3zA:
undetectable
3pneB-3f3zA:
undetectable
3pneA-3f3zA:
21.03
3pneB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 3pnfA-3f3zA:
undetectable
3pnfB-3f3zA:
undetectable
3pnfA-3f3zA:
21.03
3pnfB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3pnfA-3f3zA:
undetectable
3pnfB-3f3zA:
undetectable
3pnfA-3f3zA:
21.03
3pnfB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.35A 3pngA-3f3zA:
undetectable
3pngB-3f3zA:
undetectable
3pngA-3f3zA:
21.03
3pngB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3rqjA-3f3zA:
undetectable
3rqjB-3f3zA:
undetectable
3rqjA-3f3zA:
21.03
3rqjB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3rqjA-3f3zA:
undetectable
3rqjB-3f3zA:
undetectable
3rqjA-3f3zA:
21.03
3rqjB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 3rqmA-3f3zA:
undetectable
3rqmB-3f3zA:
undetectable
3rqmA-3f3zA:
21.03
3rqmB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 3rqmA-3f3zA:
undetectable
3rqmB-3f3zA:
undetectable
3rqmA-3f3zA:
21.03
3rqmB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3rqnA-3f3zA:
undetectable
3rqnB-3f3zA:
undetectable
3rqnA-3f3zA:
21.03
3rqnB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 3tylA-3f3zA:
undetectable
3tylB-3f3zA:
undetectable
3tylA-3f3zA:
21.03
3tylB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 3tyoA-3f3zA:
undetectable
3tyoB-3f3zA:
undetectable
3tyoA-3f3zA:
21.03
3tyoB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 3ufsA-3f3zA:
undetectable
3ufsB-3f3zA:
undetectable
3ufsA-3f3zA:
21.03
3ufsB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 3ufsA-3f3zA:
undetectable
3ufsB-3f3zA:
undetectable
3ufsA-3f3zA:
21.03
3ufsB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 3ufuA-3f3zA:
undetectable
3ufuB-3f3zA:
undetectable
3ufuA-3f3zA:
21.03
3ufuB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 3ufvA-3f3zA:
undetectable
3ufvB-3f3zA:
undetectable
3ufvA-3f3zA:
21.03
3ufvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_1
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
7 / 12 ILE A  34
GLY A  37
GLY A  40
VAL A  42
ALA A  55
LYS A  57
LEU A 155
DRK  A   1 (-4.2A)
None
None
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 (-4.6A)
0.58A 3v5wA-3f3zA:
10.8
3v5wA-3f3zA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 VAL A  42
LYS A  57
ILE A  86
ILE A 168
DRK  A   1 ( 4.9A)
DRK  A   1 (-4.1A)
DRK  A   1 ( 4.8A)
DRK  A   1 ( 4.2A)
0.55A 3warA-3f3zA:
26.5
3warA-3f3zA:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4c39A-3f3zA:
undetectable
4c39B-3f3zA:
undetectable
4c39A-3f3zA:
21.03
4c39B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 4caqA-3f3zA:
undetectable
4caqB-3f3zA:
undetectable
4caqA-3f3zA:
21.03
4caqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.04A 4coxA-3f3zA:
undetectable
4coxA-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.05A 4coxB-3f3zA:
undetectable
4coxB-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.04A 4coxD-3f3zA:
undetectable
4coxD-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 4ctpA-3f3zA:
undetectable
4ctpB-3f3zA:
undetectable
4ctpA-3f3zA:
21.03
4ctpB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 4ctqA-3f3zA:
undetectable
4ctqB-3f3zA:
undetectable
4ctqA-3f3zA:
21.03
4ctqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 4ctqA-3f3zA:
undetectable
4ctqB-3f3zA:
undetectable
4ctqA-3f3zA:
21.03
4ctqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4cttA-3f3zA:
undetectable
4cttB-3f3zA:
undetectable
4cttA-3f3zA:
21.03
4cttB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 4cttA-3f3zA:
undetectable
4cttB-3f3zA:
undetectable
4cttA-3f3zA:
21.03
4cttB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4ctvA-3f3zA:
undetectable
4ctvB-3f3zA:
undetectable
4ctvA-3f3zA:
21.03
4ctvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 4ctwA-3f3zA:
undetectable
4ctwB-3f3zA:
undetectable
4ctwA-3f3zA:
21.03
4ctwB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 4cx5A-3f3zA:
undetectable
4cx5B-3f3zA:
undetectable
4cx5A-3f3zA:
21.03
4cx5B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4cx6A-3f3zA:
undetectable
4cx6B-3f3zA:
undetectable
4cx6A-3f3zA:
21.03
4cx6B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4cx6A-3f3zA:
undetectable
4cx6B-3f3zA:
undetectable
4cx6A-3f3zA:
21.03
4cx6B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.38A 4cx7C-3f3zA:
undetectable
4cx7D-3f3zA:
undetectable
4cx7C-3f3zA:
20.85
4cx7D-3f3zA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 4d1nC-3f3zA:
undetectable
4d1nD-3f3zA:
undetectable
4d1nC-3f3zA:
20.37
4d1nD-3f3zA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4d31A-3f3zA:
undetectable
4d31B-3f3zA:
undetectable
4d31A-3f3zA:
21.03
4d31B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4fvwA-3f3zA:
undetectable
4fvwB-3f3zA:
undetectable
4fvwA-3f3zA:
21.03
4fvwB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4fvxA-3f3zA:
undetectable
4fvxB-3f3zA:
undetectable
4fvxA-3f3zA:
21.03
4fvxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 4fvxA-3f3zA:
undetectable
4fvxB-3f3zA:
undetectable
4fvxA-3f3zA:
21.03
4fvxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4fvyA-3f3zA:
undetectable
4fvyB-3f3zA:
undetectable
4fvyA-3f3zA:
21.03
4fvyB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 4fvzA-3f3zA:
undetectable
4fvzB-3f3zA:
undetectable
4fvzA-3f3zA:
21.03
4fvzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 11 VAL A  42
ALA A  55
LYS A  57
LEU A 155
ILE A 168
ASP A 169
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 (-4.6A)
DRK  A   1 ( 4.2A)
None
0.96A 4iaaA-3f3zA:
21.9
4iaaA-3f3zA:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
7 / 12 GLY A  35
VAL A  42
ALA A  55
LEU A  88
LEU A 100
GLY A 108
ILE A 168
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
None
None
DRK  A   1 ( 4.9A)
DRK  A   1 ( 4.2A)
0.56A 4ifgA-3f3zA:
29.5
4ifgA-3f3zA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
7 / 12 GLY A  35
VAL A  42
ALA A  55
LYS A  57
LEU A 100
GLY A 108
ILE A 168
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
None
DRK  A   1 ( 4.9A)
DRK  A   1 ( 4.2A)
0.64A 4ifgA-3f3zA:
29.5
4ifgA-3f3zA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
8 / 12 VAL A  42
ALA A  55
LEU A  88
LEU A 100
GLY A 108
GLU A 109
LEU A 155
ILE A 168
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
None
None
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.6A)
DRK  A   1 ( 4.2A)
0.53A 4ifgA-3f3zA:
29.5
4ifgA-3f3zA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IFG_A_1E8A601_1
(CALMODULIN-DOMAIN
PROTEIN KINASE 1)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
7 / 12 VAL A  42
ALA A  55
LYS A  57
LEU A 100
GLY A 108
LEU A 155
ILE A 168
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
None
DRK  A   1 ( 4.9A)
DRK  A   1 (-4.6A)
DRK  A   1 ( 4.2A)
0.58A 4ifgA-3f3zA:
29.5
4ifgA-3f3zA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.37A 4imtA-3f3zA:
undetectable
4imtB-3f3zA:
undetectable
4imtA-3f3zA:
21.03
4imtB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.22A 4jsfA-3f3zA:
undetectable
4jsfB-3f3zA:
undetectable
4jsfA-3f3zA:
21.03
4jsfB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 4jsfA-3f3zA:
undetectable
4jsfB-3f3zA:
undetectable
4jsfA-3f3zA:
21.03
4jsfB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4jsgA-3f3zA:
undetectable
4jsgB-3f3zA:
undetectable
4jsgA-3f3zA:
21.46
4jsgB-3f3zA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 4jshA-3f3zA:
undetectable
4jshB-3f3zA:
undetectable
4jshA-3f3zA:
21.03
4jshB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4jsiA-3f3zA:
undetectable
4jsiB-3f3zA:
undetectable
4jsiA-3f3zA:
21.03
4jsiB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4jsjA-3f3zA:
undetectable
4jsjB-3f3zA:
undetectable
4jsjA-3f3zA:
21.03
4jsjB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.37A 4k5dA-3f3zA:
undetectable
4k5dB-3f3zA:
undetectable
4k5dA-3f3zA:
21.03
4k5dB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.36A 4k5fA-3f3zA:
undetectable
4k5fB-3f3zA:
undetectable
4k5fA-3f3zA:
21.03
4k5fB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 4k5gA-3f3zA:
undetectable
4k5gB-3f3zA:
undetectable
4k5gA-3f3zA:
21.03
4k5gB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 4k5gA-3f3zA:
undetectable
4k5gB-3f3zA:
undetectable
4k5gA-3f3zA:
21.03
4k5gB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 4kcnA-3f3zA:
undetectable
4kcnB-3f3zA:
undetectable
4kcnA-3f3zA:
21.03
4kcnB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 4kcnA-3f3zA:
undetectable
4kcnB-3f3zA:
undetectable
4kcnA-3f3zA:
21.03
4kcnB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 VAL A  42
ALA A  55
MET A 102
LEU A 155
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-3.6A)
DRK  A   1 (-4.6A)
0.44A 4l9iA-3f3zA:
25.1
4l9iA-3f3zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 8 GLY A  37
VAL A  42
ALA A  55
LYS A  57
MET A 102
LEU A 155
None
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 (-3.6A)
DRK  A   1 (-4.6A)
0.86A 4l9iB-3f3zA:
22.1
4l9iB-3f3zA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4luxA-3f3zA:
undetectable
4luxB-3f3zA:
undetectable
4luxA-3f3zA:
21.03
4luxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 11 TYR A 191
ASP A 148
VAL A 132
SER A 209
GLY A 211
None
1.14A 4mmaA-3f3zA:
undetectable
4mmaA-3f3zA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.24A 4nosC-3f3zA:
undetectable
4nosD-3f3zA:
undetectable
4nosC-3f3zA:
20.66
4nosD-3f3zA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.08A 4otyA-3f3zA:
undetectable
4otyA-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.06A 4otyB-3f3zA:
undetectable
4otyB-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMZ_A_B49A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 12 ILE A  34
GLY A  35
VAL A  42
ALA A  55
MET A 102
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-3.6A)
DRK  A   1 (-4.6A)
0.67A 4qmzA-3f3zA:
22.8
4qmzA-3f3zA:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_1
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
7 / 12 VAL A  42
ALA A  55
LYS A  57
MET A  77
CYH A 105
LEU A 155
ASP A 169
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
None
DRK  A   1 (-4.1A)
DRK  A   1 (-4.6A)
None
0.77A 4r7iA-3f3zA:
21.7
4r7iA-3f3zA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.04A 4rrwC-3f3zA:
undetectable
4rrwC-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 LEU A 263
GLY A 211
ALA A 210
SER A 209
LEU A 149
None
1.04A 4rrzC-3f3zA:
undetectable
4rrzC-3f3zA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZ7_A_1E8A901_1
(CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
6 / 10 ILE A  34
ALA A  55
LYS A  57
ILE A  86
LEU A 104
LEU A 155
DRK  A   1 (-4.2A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
DRK  A   1 (-4.6A)
0.52A 4rz7A-3f3zA:
11.3
4rz7A-3f3zA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 4uchA-3f3zA:
undetectable
4uchB-3f3zA:
undetectable
4uchA-3f3zA:
20.84
4uchB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 4ugzA-3f3zA:
undetectable
4ugzB-3f3zA:
undetectable
4ugzA-3f3zA:
21.03
4ugzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 4ugzA-3f3zA:
undetectable
4ugzB-3f3zA:
undetectable
4ugzA-3f3zA:
21.03
4ugzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4uh0A-3f3zA:
undetectable
4uh0B-3f3zA:
undetectable
4uh0A-3f3zA:
21.03
4uh0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4uh2A-3f3zA:
undetectable
4uh2B-3f3zA:
undetectable
4uh2A-3f3zA:
21.03
4uh2B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4uh2A-3f3zA:
undetectable
4uh2B-3f3zA:
undetectable
4uh2A-3f3zA:
21.03
4uh2B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 4uh3A-3f3zA:
undetectable
4uh3B-3f3zA:
undetectable
4uh3A-3f3zA:
21.03
4uh3B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4uh4A-3f3zA:
undetectable
4uh4B-3f3zA:
undetectable
4uh4A-3f3zA:
21.03
4uh4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4uh5A-3f3zA:
undetectable
4uh5B-3f3zA:
undetectable
4uh5A-3f3zA:
20.84
4uh5B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 4uh6A-3f3zA:
undetectable
4uh6B-3f3zA:
undetectable
4uh6A-3f3zA:
20.84
4uh6B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 4upmA-3f3zA:
undetectable
4upmB-3f3zA:
undetectable
4upmA-3f3zA:
21.03
4upmB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 4v3uA-3f3zA:
undetectable
4v3uB-3f3zA:
undetectable
4v3uA-3f3zA:
20.37
4v3uB-3f3zA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 4v3uC-3f3zA:
undetectable
4v3uD-3f3zA:
undetectable
4v3uC-3f3zA:
20.37
4v3uD-3f3zA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 4v3yA-3f3zA:
undetectable
4v3yB-3f3zA:
undetectable
4v3yA-3f3zA:
21.03
4v3yB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.24A 5ad4A-3f3zA:
undetectable
5ad4B-3f3zA:
undetectable
5ad4A-3f3zA:
21.03
5ad4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
VAL A 251
TRP A 248
PHE A 243
None
1.47A 5ad4A-3f3zA:
undetectable
5ad4B-3f3zA:
undetectable
5ad4A-3f3zA:
21.03
5ad4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 5ad4A-3f3zA:
undetectable
5ad4B-3f3zA:
undetectable
5ad4A-3f3zA:
21.03
5ad4B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 5ad5A-3f3zA:
undetectable
5ad5B-3f3zA:
undetectable
5ad5A-3f3zA:
21.03
5ad5B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5ad5A-3f3zA:
undetectable
5ad5B-3f3zA:
undetectable
5ad5A-3f3zA:
21.03
5ad5B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 5ad8A-3f3zA:
undetectable
5ad8B-3f3zA:
undetectable
5ad8A-3f3zA:
21.03
5ad8B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5adaA-3f3zA:
undetectable
5adaB-3f3zA:
undetectable
5adaA-3f3zA:
21.03
5adaB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5adaA-3f3zA:
undetectable
5adaB-3f3zA:
undetectable
5adaA-3f3zA:
21.03
5adaB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.36A 5adbA-3f3zA:
undetectable
5adbB-3f3zA:
undetectable
5adbA-3f3zA:
21.03
5adbB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5adcA-3f3zA:
undetectable
5adcB-3f3zA:
undetectable
5adcA-3f3zA:
21.03
5adcB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5adcA-3f3zA:
undetectable
5adcB-3f3zA:
undetectable
5adcA-3f3zA:
21.03
5adcB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.28A 5addA-3f3zA:
undetectable
5addB-3f3zA:
undetectable
5addA-3f3zA:
21.03
5addB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.28A 5adeA-3f3zA:
undetectable
5adeB-3f3zA:
undetectable
5adeA-3f3zA:
21.03
5adeB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5adfA-3f3zA:
undetectable
5adfB-3f3zA:
undetectable
5adfA-3f3zA:
20.84
5adfB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5adgA-3f3zA:
undetectable
5adgB-3f3zA:
undetectable
5adgA-3f3zA:
20.84
5adgB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 5adgA-3f3zA:
undetectable
5adgB-3f3zA:
undetectable
5adgA-3f3zA:
20.84
5adgB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5adiA-3f3zA:
undetectable
5adiB-3f3zA:
undetectable
5adiA-3f3zA:
20.84
5adiB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5agkA-3f3zA:
undetectable
5agkB-3f3zA:
undetectable
5agkA-3f3zA:
21.03
5agkB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5aglA-3f3zA:
undetectable
5aglB-3f3zA:
undetectable
5aglA-3f3zA:
21.03
5aglB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5agnA-3f3zA:
undetectable
5agnB-3f3zA:
undetectable
5agnA-3f3zA:
21.03
5agnB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5agoA-3f3zA:
undetectable
5agoB-3f3zA:
undetectable
5agoA-3f3zA:
21.03
5agoB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 5agoA-3f3zA:
undetectable
5agoB-3f3zA:
undetectable
5agoA-3f3zA:
21.03
5agoB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 5agpA-3f3zA:
undetectable
5agpB-3f3zA:
undetectable
5agpA-3f3zA:
21.03
5agpB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5fvpA-3f3zA:
undetectable
5fvpB-3f3zA:
undetectable
5fvpA-3f3zA:
21.03
5fvpB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5fvqA-3f3zA:
undetectable
5fvqB-3f3zA:
undetectable
5fvqA-3f3zA:
21.03
5fvqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5fvrA-3f3zA:
undetectable
5fvrB-3f3zA:
undetectable
5fvrA-3f3zA:
21.03
5fvrB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5fvrA-3f3zA:
undetectable
5fvrB-3f3zA:
undetectable
5fvrA-3f3zA:
21.03
5fvrB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5fvsA-3f3zA:
undetectable
5fvsB-3f3zA:
undetectable
5fvsA-3f3zA:
21.03
5fvsB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5fvtA-3f3zA:
undetectable
5fvtB-3f3zA:
undetectable
5fvtA-3f3zA:
21.03
5fvtB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5fvuA-3f3zA:
undetectable
5fvuB-3f3zA:
undetectable
5fvuA-3f3zA:
20.84
5fvuB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.28A 5fvwA-3f3zA:
undetectable
5fvwB-3f3zA:
undetectable
5fvwA-3f3zA:
20.84
5fvwB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5fw0A-3f3zA:
undetectable
5fw0B-3f3zA:
undetectable
5fw0A-3f3zA:
21.03
5fw0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 5g0nA-3f3zA:
undetectable
5g0nB-3f3zA:
undetectable
5g0nA-3f3zA:
21.03
5g0nB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5g0nA-3f3zA:
undetectable
5g0nB-3f3zA:
undetectable
5g0nA-3f3zA:
21.03
5g0nB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5g0oA-3f3zA:
undetectable
5g0oB-3f3zA:
undetectable
5g0oA-3f3zA:
21.03
5g0oB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5g0oA-3f3zA:
undetectable
5g0oB-3f3zA:
undetectable
5g0oA-3f3zA:
21.03
5g0oB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5g0pA-3f3zA:
undetectable
5g0pB-3f3zA:
undetectable
5g0pA-3f3zA:
21.03
5g0pB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 GLY A  37
CYH A 105
ASP A 169
PHE A 170
None
DRK  A   1 (-4.1A)
None
None
0.84A 5hieB-3f3zA:
23.1
5hieB-3f3zA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 GLY A  37
CYH A 105
ASP A 169
PHE A 170
None
DRK  A   1 (-4.1A)
None
None
0.86A 5hieD-3f3zA:
23.3
5hieD-3f3zA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 7 GLY A  35
GLY A  37
SER A  38
GLY A  40
VAL A  42
DRK  A   1 ( 3.9A)
None
None
None
DRK  A   1 ( 4.9A)
0.76A 5izjB-3f3zA:
30.0
5izjB-3f3zA:
28.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 12 GLY A 211
MET A 214
LEU A 218
ALA A 255
PHE A 243
None
1.37A 5kc4E-3f3zA:
undetectable
5kc4E-3f3zA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 9 GLY A  35
VAL A  42
ALA A  55
ILE A  86
MET A 102
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-3.6A)
0.64A 5lw1B-3f3zA:
23.1
5lw1B-3f3zA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 9 ILE A  34
GLY A  35
VAL A  42
ALA A  55
ILE A  86
DRK  A   1 (-4.2A)
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
0.47A 5lw1B-3f3zA:
23.1
5lw1B-3f3zA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 10 GLY A  35
VAL A  42
ALA A  55
ILE A  86
LEU A 104
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-4.4A)
0.38A 5lw1E-3f3zA:
22.8
5lw1E-3f3zA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_E_ADNE401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
5 / 10 GLY A  35
VAL A  42
ALA A  55
ILE A  86
MET A 102
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.8A)
DRK  A   1 (-3.6A)
0.69A 5lw1E-3f3zA:
22.8
5lw1E-3f3zA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
8 / 12 ILE A  34
GLY A  35
VAL A  42
ALA A  55
LYS A  57
GLY A 108
GLU A 109
ILE A 168
DRK  A   1 (-4.2A)
DRK  A   1 ( 3.9A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 ( 4.9A)
DRK  A   1 (-3.4A)
DRK  A   1 ( 4.2A)
0.59A 5mafA-3f3zA:
30.8
5mafA-3f3zA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 8 ALA A  55
CYH A 105
LEU A 155
ASP A 169
DRK  A   1 (-3.4A)
DRK  A   1 (-4.1A)
DRK  A   1 (-4.6A)
None
0.72A 5owrA-3f3zA:
23.8
5owrA-3f3zA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5unrA-3f3zA:
undetectable
5unrB-3f3zA:
undetectable
5unrA-3f3zA:
21.03
5unrB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5unsA-3f3zA:
undetectable
5unsB-3f3zA:
undetectable
5unsA-3f3zA:
21.03
5unsB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5unsA-3f3zA:
undetectable
5unsB-3f3zA:
undetectable
5unsA-3f3zA:
21.03
5unsB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 5untA-3f3zA:
undetectable
5untB-3f3zA:
undetectable
5untA-3f3zA:
21.03
5untB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 5untA-3f3zA:
undetectable
5untB-3f3zA:
undetectable
5untA-3f3zA:
21.03
5untB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5unuA-3f3zA:
undetectable
5unuB-3f3zA:
undetectable
5unuA-3f3zA:
21.03
5unuB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.36A 5unuA-3f3zA:
undetectable
5unuB-3f3zA:
undetectable
5unuA-3f3zA:
21.03
5unuB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.22A 5unvA-3f3zA:
undetectable
5unvB-3f3zA:
undetectable
5unvA-3f3zA:
21.03
5unvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
VAL A 251
TRP A 248
PHE A 243
None
1.49A 5unvA-3f3zA:
undetectable
5unvB-3f3zA:
undetectable
5unvA-3f3zA:
21.03
5unvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
ARG A 260
VAL A 251
None
1.46A 5unvA-3f3zA:
undetectable
5unvB-3f3zA:
undetectable
5unvA-3f3zA:
21.03
5unvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.24A 5unvA-3f3zA:
undetectable
5unvB-3f3zA:
undetectable
5unvA-3f3zA:
21.03
5unvB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.42A 5unwA-3f3zA:
undetectable
5unwB-3f3zA:
undetectable
5unwA-3f3zA:
21.03
5unwB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.36A 5unxA-3f3zA:
undetectable
5unxB-3f3zA:
undetectable
5unxA-3f3zA:
21.03
5unxB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 5unyA-3f3zA:
undetectable
5unyB-3f3zA:
undetectable
5unyA-3f3zA:
21.03
5unyB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5unzA-3f3zA:
undetectable
5unzB-3f3zA:
undetectable
5unzA-3f3zA:
21.03
5unzB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
ARG A 260
VAL A 251
None
1.49A 5uo0A-3f3zA:
undetectable
5uo0B-3f3zA:
undetectable
5uo0A-3f3zA:
21.03
5uo0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5uo0A-3f3zA:
undetectable
5uo0B-3f3zA:
undetectable
5uo0A-3f3zA:
21.03
5uo0B-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5uo1A-3f3zA:
undetectable
5uo1B-3f3zA:
undetectable
5uo1A-3f3zA:
20.84
5uo1B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5uo1A-3f3zA:
undetectable
5uo1B-3f3zA:
undetectable
5uo1A-3f3zA:
20.84
5uo1B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5uo2A-3f3zA:
undetectable
5uo2B-3f3zA:
undetectable
5uo2A-3f3zA:
20.84
5uo2B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5uo3A-3f3zA:
undetectable
5uo3B-3f3zA:
undetectable
5uo3A-3f3zA:
20.84
5uo3B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5uo4A-3f3zA:
undetectable
5uo4B-3f3zA:
undetectable
5uo4A-3f3zA:
20.84
5uo4B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5uo4A-3f3zA:
undetectable
5uo4B-3f3zA:
undetectable
5uo4A-3f3zA:
20.84
5uo4B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5uo5A-3f3zA:
undetectable
5uo5B-3f3zA:
undetectable
5uo5A-3f3zA:
20.84
5uo5B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.19A 5uo8A-3f3zA:
undetectable
5uo8B-3f3zA:
0.0
5uo8A-3f3zA:
21.22
5uo8B-3f3zA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.23A 5uo8C-3f3zA:
0.0
5uo8D-3f3zA:
0.0
5uo8C-3f3zA:
21.22
5uo8D-3f3zA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5uo9C-3f3zA:
undetectable
5uo9D-3f3zA:
undetectable
5uo9C-3f3zA:
21.22
5uo9D-3f3zA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5uodA-3f3zA:
undetectable
5uodB-3f3zA:
undetectable
5uodA-3f3zA:
21.12
5uodB-3f3zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.20A 5vujA-3f3zA:
undetectable
5vujB-3f3zA:
undetectable
5vujA-3f3zA:
21.03
5vujB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
VAL A 251
TRP A 248
PHE A 243
None
1.49A 5vujA-3f3zA:
undetectable
5vujB-3f3zA:
undetectable
5vujA-3f3zA:
21.03
5vujB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
ARG A 260
VAL A 251
None
1.48A 5vujA-3f3zA:
undetectable
5vujB-3f3zA:
undetectable
5vujA-3f3zA:
21.03
5vujB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.24A 5vujA-3f3zA:
undetectable
5vujB-3f3zA:
undetectable
5vujA-3f3zA:
21.03
5vujB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 5vukA-3f3zA:
undetectable
5vukB-3f3zA:
undetectable
5vukA-3f3zA:
21.03
5vukB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 5vukA-3f3zA:
undetectable
5vukB-3f3zA:
undetectable
5vukA-3f3zA:
21.03
5vukB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5vulA-3f3zA:
undetectable
5vulB-3f3zA:
undetectable
5vulA-3f3zA:
21.03
5vulB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5vulA-3f3zA:
undetectable
5vulB-3f3zA:
undetectable
5vulA-3f3zA:
21.03
5vulB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5vumA-3f3zA:
undetectable
5vumB-3f3zA:
undetectable
5vumA-3f3zA:
21.03
5vumB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5vumA-3f3zA:
undetectable
5vumB-3f3zA:
undetectable
5vumA-3f3zA:
21.03
5vumB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 5vunA-3f3zA:
undetectable
5vunB-3f3zA:
undetectable
5vunA-3f3zA:
21.03
5vunB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5vunA-3f3zA:
undetectable
5vunB-3f3zA:
undetectable
5vunA-3f3zA:
21.03
5vunB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.27A 5vuoA-3f3zA:
undetectable
5vuoB-3f3zA:
undetectable
5vuoA-3f3zA:
21.03
5vuoB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 5vuoA-3f3zA:
undetectable
5vuoB-3f3zA:
undetectable
5vuoA-3f3zA:
21.03
5vuoB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5vupA-3f3zA:
undetectable
5vupB-3f3zA:
undetectable
5vupA-3f3zA:
21.03
5vupB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5vupA-3f3zA:
undetectable
5vupB-3f3zA:
undetectable
5vupA-3f3zA:
21.03
5vupB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5vuqA-3f3zA:
undetectable
5vuqB-3f3zA:
undetectable
5vuqA-3f3zA:
21.03
5vuqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 5vuqA-3f3zA:
undetectable
5vuqB-3f3zA:
undetectable
5vuqA-3f3zA:
21.03
5vuqB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5vurA-3f3zA:
undetectable
5vurB-3f3zA:
undetectable
5vurA-3f3zA:
21.03
5vurB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.35A 5vusA-3f3zA:
undetectable
5vusB-3f3zA:
undetectable
5vusA-3f3zA:
21.03
5vusB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 5vusA-3f3zA:
undetectable
5vusB-3f3zA:
undetectable
5vusA-3f3zA:
21.03
5vusB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5vutA-3f3zA:
undetectable
5vutB-3f3zA:
undetectable
5vutA-3f3zA:
21.03
5vutB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 5vutA-3f3zA:
undetectable
5vutB-3f3zA:
undetectable
5vutA-3f3zA:
21.03
5vutB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5vuuA-3f3zA:
undetectable
5vuuB-3f3zA:
undetectable
5vuuA-3f3zA:
21.03
5vuuB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 5vuuA-3f3zA:
undetectable
5vuuB-3f3zA:
undetectable
5vuuA-3f3zA:
21.03
5vuuB-3f3zA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5vuvA-3f3zA:
undetectable
5vuvB-3f3zA:
undetectable
5vuvA-3f3zA:
20.84
5vuvB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 5vuvA-3f3zA:
undetectable
5vuvB-3f3zA:
undetectable
5vuvA-3f3zA:
20.84
5vuvB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 5vuwA-3f3zA:
undetectable
5vuwB-3f3zA:
undetectable
5vuwA-3f3zA:
20.84
5vuwB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 5vuwA-3f3zA:
undetectable
5vuwB-3f3zA:
undetectable
5vuwA-3f3zA:
20.84
5vuwB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5vuxA-3f3zA:
undetectable
5vuxB-3f3zA:
undetectable
5vuxA-3f3zA:
20.84
5vuxB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.37A 5vuyA-3f3zA:
undetectable
5vuyB-3f3zA:
undetectable
5vuyA-3f3zA:
20.84
5vuyB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 5vuzA-3f3zA:
undetectable
5vuzB-3f3zA:
undetectable
5vuzA-3f3zA:
20.84
5vuzB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.29A 5vuzA-3f3zA:
undetectable
5vuzB-3f3zA:
undetectable
5vuzA-3f3zA:
20.84
5vuzB-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 5vv0A-3f3zA:
undetectable
5vv0B-3f3zA:
undetectable
5vv0A-3f3zA:
20.84
5vv0B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5vv0A-3f3zA:
undetectable
5vv0B-3f3zA:
undetectable
5vv0A-3f3zA:
20.84
5vv0B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5vv1A-3f3zA:
undetectable
5vv1B-3f3zA:
undetectable
5vv1A-3f3zA:
20.84
5vv1B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 5vv1A-3f3zA:
undetectable
5vv1B-3f3zA:
undetectable
5vv1A-3f3zA:
20.84
5vv1B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 5vv2A-3f3zA:
undetectable
5vv2B-3f3zA:
undetectable
5vv2A-3f3zA:
20.84
5vv2B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 5vv2A-3f3zA:
undetectable
5vv2B-3f3zA:
undetectable
5vv2A-3f3zA:
20.84
5vv2B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.35A 5vv3A-3f3zA:
undetectable
5vv3B-3f3zA:
undetectable
5vv3A-3f3zA:
20.84
5vv3B-3f3zA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 VAL A  42
LYS A  57
ILE A  86
ILE A 168
DRK  A   1 ( 4.9A)
DRK  A   1 (-4.1A)
DRK  A   1 ( 4.8A)
DRK  A   1 ( 4.2A)
0.47A 5ywmX-3f3zA:
26.1
5ywmX-3f3zA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 6auqA-3f3zA:
undetectable
6auqB-3f3zA:
undetectable
6auqA-3f3zA:
14.62
6auqB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 6aurA-3f3zA:
undetectable
6aurB-3f3zA:
undetectable
6aurA-3f3zA:
14.62
6aurB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 6aurA-3f3zA:
undetectable
6aurB-3f3zA:
undetectable
6aurA-3f3zA:
14.62
6aurB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 6ausA-3f3zA:
undetectable
6ausB-3f3zA:
undetectable
6ausA-3f3zA:
14.62
6ausB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 6ausA-3f3zA:
undetectable
6ausB-3f3zA:
undetectable
6ausA-3f3zA:
14.62
6ausB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.33A 6autA-3f3zA:
undetectable
6autB-3f3zA:
undetectable
6autA-3f3zA:
14.62
6autB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 6auuA-3f3zA:
undetectable
6auuB-3f3zA:
undetectable
6auuA-3f3zA:
14.62
6auuB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 6auuA-3f3zA:
undetectable
6auuB-3f3zA:
undetectable
6auuA-3f3zA:
14.62
6auuB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 6auvA-3f3zA:
undetectable
6auvB-3f3zA:
undetectable
6auvA-3f3zA:
14.62
6auvB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 6auwA-3f3zA:
undetectable
6auwB-3f3zA:
undetectable
6auwA-3f3zA:
14.62
6auwB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 6auwA-3f3zA:
undetectable
6auwB-3f3zA:
undetectable
6auwA-3f3zA:
14.62
6auwB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 6auxA-3f3zA:
undetectable
6auxB-3f3zA:
undetectable
6auxA-3f3zA:
14.62
6auxB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.34A 6auxA-3f3zA:
undetectable
6auxB-3f3zA:
undetectable
6auxA-3f3zA:
14.62
6auxB-3f3zA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.32A 6auyA-3f3zA:
undetectable
6auyB-3f3zA:
undetectable
6auyA-3f3zA:
13.85
6auyB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.28A 6auzA-3f3zA:
undetectable
6auzB-3f3zA:
undetectable
6auzA-3f3zA:
13.85
6auzB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 6av0A-3f3zA:
undetectable
6av0B-3f3zA:
undetectable
6av0A-3f3zA:
13.85
6av0B-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.30A 6av1A-3f3zA:
undetectable
6av1B-3f3zA:
undetectable
6av1A-3f3zA:
13.85
6av1B-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.31A 6av4A-3f3zA:
undetectable
6av4B-3f3zA:
undetectable
6av4A-3f3zA:
13.85
6av4B-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.34A 6av5A-3f3zA:
undetectable
6av5B-3f3zA:
undetectable
6av5A-3f3zA:
13.85
6av5B-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 6 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.30A 6av6C-3f3zA:
0.0
6av6D-3f3zA:
0.1
6av6C-3f3zA:
19.67
6av6D-3f3zA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.26A 6av6C-3f3zA:
undetectable
6av6D-3f3zA:
0.1
6av6C-3f3zA:
19.67
6av6D-3f3zA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.33A 6cicA-3f3zA:
undetectable
6cicB-3f3zA:
undetectable
6cicA-3f3zA:
13.85
6cicB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.31A 6cicA-3f3zA:
undetectable
6cicB-3f3zA:
undetectable
6cicA-3f3zA:
13.85
6cicB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 ARG A 260
TRP A 248
PHE A 243
GLU A 245
None
1.29A 6cidA-3f3zA:
undetectable
6cidB-3f3zA:
undetectable
6cidA-3f3zA:
13.85
6cidB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
4 / 7 TRP A 248
PHE A 243
GLU A 245
ARG A 260
None
1.32A 6cidA-3f3zA:
undetectable
6cidB-3f3zA:
undetectable
6cidA-3f3zA:
13.85
6cidB-3f3zA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum)
3 / 3 GLU A 207
LEU A 262
ARG A 261
GOL  A 296 (-3.0A)
None
None
0.70A 6d8fA-3f3zA:
undetectable
6d8fA-3f3zA:
15.74