SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QLT_A_ACTA601_0 (VANILLYL-ALCOHOL OXIDASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	4 / 5	TYR A 91 PHE A 14 ILE A 15 TYR A 76	None	1.37A	1qltA-3f40A: undetectable	1qltA-3f40A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QLT_B_ACTB601_0 (VANILLYL-ALCOHOL OXIDASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	4 / 5	TYR A 91 PHE A 14 ILE A 15 TYR A 76	None	1.39A	1qltB-3f40A: undetectable	1qltB-3f40A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VAO_A_ACTA601_0 (VANILLYL-ALCOHOL OXIDASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	4 / 5	TYR A 91 PHE A 14 ILE A 15 TYR A 76	None	1.35A	1vaoA-3f40A: undetectable	1vaoA-3f40A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VAO_B_ACTB601_0 (VANILLYL-ALCOHOL OXIDASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	4 / 5	TYR A 91 PHE A 14 ILE A 15 TYR A 76	None	1.35A	1vaoB-3f40A: undetectable	1vaoB-3f40A: 9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AY4_A_TPFA506_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	5 / 10	TYR A 60 ALA A 86 PHE A 105 LEU A 101 CYH A 73	None	1.24A	6ay4A-3f40A: undetectable	6ay4A-3f40A: 13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AY4_A_TPFA506_1 (CYP51, STEROL 14ALPHA-DEMETHYLASE)	3f40	UNCHARACTERIZED NTF2-LIKE PROTEIN (Cytophaga hutchinsonii)	5 / 10	TYR A 60 MET A 80 ALA A 86 PHE A 105 LEU A 101	None	1.48A	6ay4A-3f40A: undetectable	6ay4A-3f40A: 13.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QLT_A_ACTA601_0","VANILLYL-ALCOHOL OXIDASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",4,"TYR A  91;PHE A  14;ILE A  15;TYR A  76","None","1.37A","1qltA-3f40A:undetectable","1qltA-3f40A:9.52"],["1QLT_B_ACTB601_0","VANILLYL-ALCOHOL OXIDASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",4,"TYR A  91;PHE A  14;ILE A  15;TYR A  76","None","1.39A","1qltB-3f40A:undetectable","1qltB-3f40A:9.52"],["1VAO_A_ACTA601_0","VANILLYL-ALCOHOL OXIDASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",4,"TYR A  91;PHE A  14;ILE A  15;TYR A  76","None","1.35A","1vaoA-3f40A:undetectable","1vaoA-3f40A:9.52"],["1VAO_B_ACTB601_0","VANILLYL-ALCOHOL OXIDASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",4,"TYR A  91;PHE A  14;ILE A  15;TYR A  76","None","1.35A","1vaoB-3f40A:undetectable","1vaoB-3f40A:9.52"],["6AY4_A_TPFA506_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",5,"TYR A  60;ALA A  86;PHE A 105;LEU A 101;CYH A  73","None","1.24A","6ay4A-3f40A:undetectable","6ay4A-3f40A:13.70"],["6AY4_A_TPFA506_1","CYP51, STEROL 14ALPHA-DEMETHYLASE","3f40","UNCHARACTERIZED NTF2-LIKE PROTEIN","Cytophaga hutchinsonii",5,"TYR A  60;MET A  80;ALA A  86;PHE A 105;LEU A 101","None","1.48A","6ay4A-3f40A:undetectable","6ay4A-3f40A:13.70"]]