SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f4a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 7 VAL A  36
LEU A 118
LEU A  66
LEU A  69
 None
 0.85A 1cqpA-3f4aA:
undetectable
1cqpB-3f4aA:
undetectable		 1cqpA-3f4aA:
22.28
1cqpB-3f4aA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 8 TRP A  20
THR A  27
TRP A 119
LEU A  29
 SO4  A 152 (-4.2A)
SO4  A 152 (-4.2A)
None
None
 1.38A 1uw6A-3f4aA:
undetectable
1uw6B-3f4aA:
undetectable		 1uw6A-3f4aA:
21.17
1uw6B-3f4aA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  48
LEU A  17
PHE A  33
GLY A  24
 None
 0.99A 3sj1X-3f4aA:
undetectable		 3sj1X-3f4aA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 8 TRP A  20
THR A  27
TRP A 119
ARG A  30
 SO4  A 152 (-4.2A)
SO4  A 152 (-4.2A)
None
None
 1.48A 3wipD-3f4aA:
undetectable
3wipE-3f4aA:
undetectable		 3wipD-3f4aA:
22.27
3wipE-3f4aA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  53
GLY A  97
ALA A 100
SER A  99
LEU A 103
 None
 1.05A 5jw1A-3f4aA:
undetectable		 5jw1A-3f4aA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3f4a UNCHARACTERIZED
PROTEIN YGR203W
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 121
PHE A 125
LEU A  17
PHE A  33
 None
 1.13A 5x1fC-3f4aA:
undetectable
5x1fJ-3f4aA:
undetectable		 5x1fC-3f4aA:
18.18
5x1fJ-3f4aA:
13.69