SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f4f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3f4f DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		5 / 12 TYR A  31
GLY A  30
ALA A  28
ALA A  66
ILE A 116
 None
 1.17A 1nt2A-3f4fA:
undetectable		 1nt2A-3f4fA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3f4f DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
None
None
UMP  A 200 (-3.6A)
 0.77A 3wriA-3f4fA:
undetectable		 3wriA-3f4fA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3f4f DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
None
None
UMP  A 200 (-3.6A)
 0.77A 3wriB-3f4fA:
undetectable		 3wriB-3f4fA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3f4f DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 117
GLY A  63
ILE A  53
VAL A  92
 None
None
None
UMP  A 200 (-3.6A)
 0.70A 3wrkA-3f4fA:
undetectable		 3wrkA-3f4fA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3f4f DEOXYURIDINE
5'-TRIPHOSPHATE
NUCLEOTIDOHYDROLASE
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 121
GLY A  60
LYS A 119
 None
 0.75A 4k50A-3f4fA:
undetectable		 4k50A-3f4fA:
16.97