SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f4l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3f4l PUTATIVE
OXIDOREDUCTASE YHHX
(Escherichia
coli) 		4 / 6 GLY A   9
THR A  15
THR A  14
ILE A  34
 None
 0.93A 1gtnD-3f4lA:
undetectable
1gtnE-3f4lA:
undetectable		 1gtnD-3f4lA:
13.91
1gtnE-3f4lA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3f4l PUTATIVE
OXIDOREDUCTASE YHHX
(Escherichia
coli) 		5 / 12 ASN A 325
VAL A 223
ALA A 212
ALA A 171
ILE A 184
 None
 1.28A 3dl9B-3f4lA:
undetectable		 3dl9B-3f4lA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3f4l PUTATIVE
OXIDOREDUCTASE YHHX
(Escherichia
coli) 		5 / 12 GLU A 145
LEU A 277
VAL A 238
GLY A 240
ILE A 146
 None
 0.85A 5vopA-3f4lA:
undetectable		 5vopA-3f4lA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3f4l PUTATIVE
OXIDOREDUCTASE YHHX
(Escherichia
coli) 		3 / 3 TYR A 173
ASP A 169
GLN A 168
 None
 0.89A 6g1pA-3f4lA:
undetectable		 6g1pA-3f4lA:
23.48