SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f4s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		4 / 4 LEU A  76
PRO A  37
LEU A  33
ARG A  80
 None
 1.32A 2qd2A-3f4sA:
undetectable		 2qd2A-3f4sA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		4 / 4 LEU A  76
PRO A  37
LEU A  33
ARG A  80
 None
 1.40A 3hcoA-3f4sA:
undetectable		 3hcoA-3f4sA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		4 / 4 PRO A  37
LEU A  33
ILE A  78
ARG A  80
 None
 1.47A 4f4dA-3f4sA:
undetectable		 4f4dA-3f4sA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		4 / 5 HIS A  96
ALA A  92
HIS A  81
TYR A 104
 None
 1.16A 4gboA-3f4sA:
undetectable		 4gboA-3f4sA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 TYR A  98
GLU A 102
VAL A 111
ILE A 132
LEU A  94
 None
 1.34A 4k36A-3f4sA:
undetectable		 4k36A-3f4sA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 TYR A  98
GLU A 102
VAL A 111
ILE A 132
LEU A  94
 None
 1.31A 4k36B-3f4sA:
undetectable		 4k36B-3f4sA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 TYR A  98
GLU A 102
VAL A 111
ILE A 132
LEU A  94
 None
 1.28A 4k38A-3f4sA:
undetectable
4k38D-3f4sA:
undetectable		 4k38A-3f4sA:
21.11
4k38D-3f4sA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 TYR A  98
GLU A 102
VAL A 111
ILE A 132
LEU A  94
 None
 1.34A 4k38B-3f4sA:
undetectable		 4k38B-3f4sA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 GLY A  88
PHE A 202
ILE A 177
GLY A 194
THR A  50
 None
 1.13A 4zdyA-3f4sA:
undetectable		 4zdyA-3f4sA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 GLY A  88
PHE A 202
ILE A 177
GLY A 194
THR A  50
 None
 1.13A 4ze2A-3f4sA:
undetectable		 4ze2A-3f4sA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		5 / 12 GLY A  88
PHE A 202
ILE A 177
GLY A 194
THR A  50
 None
 1.13A 5eslA-3f4sA:
undetectable		 5eslA-3f4sA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN
(Wolbachia
endosymbiont
of
Drosophila
melanogaster) 		4 / 5 HIS A  96
ALA A  92
HIS A  81
TYR A 104
 None
 1.14A 5uizA-3f4sA:
undetectable		 5uizA-3f4sA:
19.25