SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f65'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		3 / 3 VAL A  82
VAL A  41
TRP A  84
 None
 0.89A 1av2C-3f65A:
undetectable
1av2D-3f65A:
undetectable		 1av2C-3f65A:
4.93
1av2D-3f65A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		3 / 3 VAL A  82
VAL A  41
TRP A  84
 None
 0.88A 1w5uC-3f65A:
undetectable
1w5uD-3f65A:
undetectable		 1w5uC-3f65A:
4.93
1w5uD-3f65A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		3 / 3 VAL A  41
TRP A  84
VAL A  82
 None
 0.73A 2izqA-3f65A:
undetectable
2izqB-3f65A:
undetectable		 2izqA-3f65A:
4.93
2izqB-3f65A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		4 / 8 PHE A  55
VAL A  51
LEU A  66
PRO A  53
 None
 1.06A 3bgdB-3f65A:
undetectable		 3bgdB-3f65A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		3 / 3 VAL A  82
VAL A  41
TRP A  84
 None
 0.87A 3l8lA-3f65A:
undetectable
3l8lB-3f65A:
undetectable		 3l8lA-3f65A:
4.93
3l8lB-3f65A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		3 / 3 VAL A  82
VAL A  41
TRP A  84
 None
 0.95A 3l8lC-3f65A:
undetectable
3l8lD-3f65A:
undetectable		 3l8lC-3f65A:
4.93
3l8lD-3f65A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		5 / 10 ARG A 112
ALA A 148
ARG A   8
TYR A 145
ILE A  10
 None
None
MPD  A 225 (-3.7A)
None
None
 1.30A 3retA-3f65A:
undetectable
3retB-3f65A:
undetectable		 3retA-3f65A:
19.00
3retB-3f65A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		4 / 6 ILE A 149
TRP A  84
ILE A  40
MET A 174
 None
 1.22A 3welA-3f65A:
undetectable		 3welA-3f65A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		5 / 12 PHE A  31
ASN A  24
GLY A  33
GLN A  88
ASP A  89
 None
 1.35A 4pevA-3f65A:
undetectable		 4pevA-3f65A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		4 / 7 ILE A 149
PHE A 173
VAL A 188
ILE A 202
 None
 0.90A 4zzbC-3f65A:
undetectable
4zzbD-3f65A:
undetectable		 4zzbC-3f65A:
22.61
4zzbD-3f65A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3f65 CHAPERONE PROTEIN
FAEE
(Escherichia
coli) 		4 / 8 LEU A 152
VAL A 185
VAL A 181
ILE A 127
 None
 0.71A 5y9mA-3f65A:
undetectable		 5y9mA-3f65A:
17.18