SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f67'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		5 / 10 GLY A 227
LEU A 232
PHE A 119
TRP A 228
THR A 117
 None
 1.21A 1a8uA-3f67A:
16.8		 1a8uA-3f67A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		5 / 10 GLY A 227
LEU A 232
PHE A 119
TRP A 228
THR A 117
 None
 1.24A 1a8uB-3f67A:
16.6		 1a8uB-3f67A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 7 ARG A  67
GLY A 122
ILE A 125
PRO A  62
 None
 0.75A 2fxdB-3f67A:
undetectable		 2fxdB-3f67A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 7 ALA A 101
PHE A  66
PRO A  16
THR A   6
 None
None
EDO  A 239 ( 4.9A)
None
 1.02A 2q6oA-3f67A:
2.6		 2q6oA-3f67A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A  20
THR A 117
PHE A 119
ILE A  45
ASP A  47
 None
 1.08A 2v95A-3f67A:
undetectable		 2v95A-3f67A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		3 / 3 PRO A  71
GLY A  40
TYR A  65
 None
 0.69A 2vouB-3f67A:
undetectable		 2vouB-3f67A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		3 / 3 PRO A  71
GLY A  40
TYR A  65
 None
 0.68A 2vouC-3f67A:
undetectable		 2vouC-3f67A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y4N_B_PACB503_0
(PHENYLACETATE-COENZY
ME A LIGASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 4 SER A 154
GLY A 122
GLY A 144
LYS A 145
 None
 1.30A 2y4nB-3f67A:
2.5		 2y4nB-3f67A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 6 LEU A 128
TYR A 129
ALA A 139
LEU A  94
 None
 1.17A 3rd0A-3f67A:
undetectable		 3rd0A-3f67A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 130
ASP A  90
ARG A 124
LEU A  64
ILE A  33
 None
 1.01A 4m2xA-3f67A:
undetectable		 4m2xA-3f67A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 130
ASP A  90
ARG A 124
LEU A  64
ILE A  33
 None
 0.98A 4m2xE-3f67A:
undetectable		 4m2xE-3f67A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 8 HIS A  44
TYR A 215
LEU A  48
THR A 117
 None
 1.07A 5hs6A-3f67A:
4.5		 5hs6A-3f67A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		4 / 4 GLY A 171
LEU A 170
VAL A 202
GLU A 200
 None
 1.32A 5yw0A-3f67A:
undetectable		 5yw0A-3f67A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3f67 PUTATIVE
DIENELACTONE
HYDROLASE
(Klebsiella
pneumoniae) 		3 / 3 TRP A 103
ILE A  60
GLU A   5
 None
None
EDO  A 239 (-2.9A)
 0.87A 6hcxA-3f67A:
undetectable		 6hcxA-3f67A:
14.53