SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f6a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		4 / 8 LEU A  31
ILE A  46
LYS A  50
THR A 105
 None
 0.89A 1sbrA-3f6aA:
undetectable		 1sbrA-3f6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		5 / 12 SER A 117
GLU A 116
GLY A  33
TYR A 101
VAL A   9
 None
 1.36A 2kceA-3f6aA:
undetectable		 2kceA-3f6aA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		4 / 8 VAL A  12
THR A 104
THR A 106
ASP A  15
 None
 0.79A 2kotB-3f6aA:
undetectable		 2kotB-3f6aA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		3 / 3 GLU A  51
HIS A  34
GLU A  48
 None
 0.83A 2x45B-3f6aA:
undetectable		 2x45B-3f6aA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		3 / 3 GLU A  51
HIS A  34
GLU A  48
 None
 0.80A 2x45C-3f6aA:
undetectable		 2x45C-3f6aA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		3 / 3 ASN A  81
ASN A  61
GLU A  42
 None
 0.91A 3kpdC-3f6aA:
undetectable		 3kpdC-3f6aA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		4 / 7 ILE A 134
LEU A 139
HIS A 132
ALA A 131
 None
 0.81A 4g77A-3f6aA:
undetectable		 4g77A-3f6aA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		5 / 12 GLU A  52
GLY A  32
GLY A  54
LEU A 120
PRO A 112
 None
 1.22A 4uinH-3f6aA:
undetectable
4uinL-3f6aA:
undetectable		 4uinH-3f6aA:
17.11
4uinL-3f6aA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 3f6a HYDROLASE, NUDIX
FAMILY
(Clostridium
perfringens) 		3 / 3 VAL A   7
GLU A 116
GLU A  51
 None
 0.93A 5jsdB-3f6aA:
undetectable
5jsdC-3f6aA:
undetectable		 5jsdB-3f6aA:
12.43
5jsdC-3f6aA:
12.43