SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 11 ILE A 148
ALA A 104
ILE A  27
ILE A 111
ILE A 100
 None
 1.08A 1dyrA-3f6mA:
undetectable		 1dyrA-3f6mA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 6 MET A   1
LEU A  50
ALA A  53
LEU A  51
 None
 1.18A 1etb1-3f6mA:
undetectable		 1etb1-3f6mA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		6 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  27
ILE A  22
 None
 1.20A 1hshA-3f6mA:
undetectable		 1hshA-3f6mA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		6 / 12 GLY A  39
ASP A   8
ILE A 100
GLY A 147
PRO A 105
ILE A  22
 None
 1.22A 1hshA-3f6mA:
undetectable		 1hshA-3f6mA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 9 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 1.04A 1hxwA-3f6mA:
undetectable		 1hxwA-3f6mA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 ILE A 100
ASP A  40
LEU A  43
ILE A 129
LEU A  96
 None
 1.22A 1rh3A-3f6mA:
undetectable		 1rh3A-3f6mA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 11 ILE A 148
VAL A  41
ALA A  42
ILE A  98
PHE A   7
 None
 1.19A 1uduA-3f6mA:
undetectable		 1uduA-3f6mA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A   6
CYH A 150
ASP A  48
ALA A  45
ALA A  42
 None
 1.18A 2br4B-3f6mA:
undetectable		 2br4B-3f6mA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  18
TYR A  29
ASP A  38
SER A  37
ALA A  35
 None
 1.09A 2br4C-3f6mA:
undetectable		 2br4C-3f6mA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		6 / 12 GLY A  39
ASP A   8
GLY A 147
PHE A 141
PRO A 105
ILE A  22
 None
 1.17A 2fxeA-3f6mA:
undetectable		 2fxeA-3f6mA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 0.99A 2hs2B-3f6mA:
undetectable		 2hs2B-3f6mA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 1.03A 2qhcB-3f6mA:
undetectable		 2qhcB-3f6mA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 ASP A  40
ILE A  21
ASP A  74
ASP A 121
ALA A 119
 None
 1.23A 2qmjA-3f6mA:
undetectable		 2qmjA-3f6mA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		6 / 12 GLY A  39
ASP A   8
ILE A 100
GLY A 147
PRO A 105
ILE A  22
 None
 1.12A 2rkgA-3f6mA:
undetectable		 2rkgA-3f6mA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 1.07A 2z54A-3f6mA:
undetectable		 2z54A-3f6mA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 5 LEU A 156
ILE A 129
ARG A 115
TYR A  83
 None
 1.29A 2zlcA-3f6mA:
undetectable		 2zlcA-3f6mA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 1.01A 3d1zB-3f6mA:
undetectable		 3d1zB-3f6mA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 11 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 0.97A 3ektD-3f6mA:
undetectable		 3ektD-3f6mA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		6 / 12 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  27
ILE A  22
 None
 1.11A 3s54B-3f6mA:
undetectable		 3s54B-3f6mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 10 GLY A  39
ASP A   8
GLY A 147
PRO A 105
ILE A  22
 None
 0.97A 3ttpA-3f6mA:
undetectable		 3ttpA-3f6mA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 8 LEU A 122
ILE A 129
ASN A 130
ILE A  98
 None
 0.77A 3wxoA-3f6mA:
undetectable		 3wxoA-3f6mA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 GLY A 147
LEU A  43
HIS A  44
ASP A   8
GLY A  24
 None
 1.02A 4blvA-3f6mA:
undetectable		 4blvA-3f6mA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 8 GLY A  72
GLY A  39
ILE A  21
LEU A  43
 None
 0.79A 4mwzB-3f6mA:
undetectable		 4mwzB-3f6mA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		5 / 12 LEU A  50
GLY A  23
ALA A  46
GLY A  39
ASP A  38
 None
 1.15A 4n09A-3f6mA:
undetectable		 4n09A-3f6mA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		4 / 4 VAL A  25
GLY A  24
ARG A  76
VAL A 116
 None
 1.26A 5d4nA-3f6mA:
undetectable
5d4nB-3f6mA:
undetectable		 5d4nA-3f6mA:
24.40
5d4nB-3f6mA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		3 / 3 HIS A  10
ASP A   8
HIS A  44
 None
 0.67A 5oexA-3f6mA:
undetectable		 5oexA-3f6mA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		3 / 3 HIS A  10
ASP A   8
HIS A  44
 None
 0.66A 5oexB-3f6mA:
undetectable		 5oexB-3f6mA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		3 / 3 HIS A  10
ASP A   8
HIS A  44
 None
 0.71A 5oexC-3f6mA:
undetectable		 5oexC-3f6mA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3f6m 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Yersinia
pestis) 		3 / 3 HIS A  10
ASP A   8
HIS A  44
 None
 0.69A 5oexD-3f6mA:
undetectable		 5oexD-3f6mA:
18.10