SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		4 / 4 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.61A 1fbmD-3f6pA:
undetectable		 1fbmD-3f6pA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		4 / 5 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.68A 1fbmE-3f6pA:
undetectable		 1fbmE-3f6pA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		5 / 12 ALA A  32
GLU A  44
ALA A  38
LEU A   6
PRO A  47
 None
 1.15A 1mjqC-3f6pA:
undetectable
1mjqD-3f6pA:
undetectable		 1mjqC-3f6pA:
22.73
1mjqD-3f6pA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		5 / 10 GLU A  44
ALA A  38
LEU A   6
PRO A  47
ALA A  32
 None
 1.17A 1mjqG-3f6pA:
undetectable
1mjqH-3f6pA:
undetectable		 1mjqG-3f6pA:
22.73
1mjqH-3f6pA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		5 / 12 ALA A  32
GLU A  44
ALA A  38
LEU A   6
PRO A  47
 None
 1.16A 1mjqI-3f6pA:
undetectable
1mjqJ-3f6pA:
undetectable		 1mjqI-3f6pA:
22.73
1mjqJ-3f6pA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF
(Bacillus
subtilis) 		4 / 4 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.80A 1mz9D-3f6pA:
undetectable		 1mz9D-3f6pA:
16.07