SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f6q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLB_A_TRPA901_0 (PROTEIN ARGONAUTE-2)	3f6q	LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAIN ING DOMAIN PROTEIN 1 (Homo sapiens)	3 / 3	VAL B 37 ALA B 39 PHE B 45	None	0.84A	4olbA-3f6qB: undetectable	4olbA-3f6qB: 6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5N_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	3f6q	LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAIN ING DOMAIN PROTEIN 1 (Homo sapiens)	3 / 3	VAL B 37 ALA B 39 PHE B 45	None	0.86A	4w5nA-3f6qB: undetectable	4w5nA-3f6qB: 6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CI6_A_NBOA607_1 (SERUM ALBUMIN)	3f6q	LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAIN ING DOMAIN PROTEIN 1 (Homo sapiens)	4 / 7	ASN B 25 LYS B 22 GLU B 33 LEU B 30	None	0.82A	6ci6A-3f6qB: undetectable	6ci6A-3f6qB: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	3f6q	LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAIN ING DOMAIN PROTEIN 1 (Homo sapiens)	4 / 8	PHE B 45 VAL B 24 SER B 26 TYR B 31	None	1.17A	6huoC-3f6qB: undetectable 6huoD-3f6qB: undetectable	6huoC-3f6qB: 19.28 6huoD-3f6qB: 11.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4OLB_A_TRPA901_0","PROTEIN ARGONAUTE-2","3f6q","LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1","Homo sapiens",3,"VAL B  37;ALA B  39;PHE B  45","None","0.84A","4olbA-3f6qB:undetectable","4olbA-3f6qB:6.18"],["4W5N_A_IPHA901_0","PROTEIN ARGONAUTE-2","3f6q","LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1","Homo sapiens",3,"VAL B  37;ALA B  39;PHE B  45","None","0.86A","4w5nA-3f6qB:undetectable","4w5nA-3f6qB:6.18"],["6CI6_A_NBOA607_1","SERUM ALBUMIN","3f6q","LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1","Homo sapiens",4,"ASN B  25;LYS B  22;GLU B  33;LEU B  30","None","0.82A","6ci6A-3f6qB:undetectable","6ci6A-3f6qB:25.00"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","3f6q","LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 1","Homo sapiens",4,"PHE B  45;VAL B  24;SER B  26;TYR B  31","None","1.17A","6huoC-3f6qB:undetectable;6huoD-3f6qB:undetectable","6huoC-3f6qB:19.28;6huoD-3f6qB:11.69"]]