SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		6 / 7 THR A  12
ASN A  14
TRP A  60
GLY A  94
ASP A  95
TYR A  98
 FMN  A 149 (-3.1A)
FMN  A 149 (-3.9A)
FMN  A 149 (-4.0A)
FMN  A 149 (-2.9A)
None
FMN  A 149 (-3.5A)
 0.30A 1bu5A-3f6rA:
28.3		 1bu5A-3f6rA:
45.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		6 / 8 THR A  12
ASN A  14
TRP A  60
GLY A  94
ASP A  95
TYR A  98
 FMN  A 149 (-3.1A)
FMN  A 149 (-3.9A)
FMN  A 149 (-4.0A)
FMN  A 149 (-2.9A)
None
FMN  A 149 (-3.5A)
 0.31A 1bu5B-3f6rA:
28.2		 1bu5B-3f6rA:
45.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  54
ALA A  19
LEU A  35
VAL A  33
ILE A 108
 None
 1.07A 1s9pA-3f6rA:
undetectable		 1s9pA-3f6rA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 ALA A 141
ASP A 143
ILE A 120
VAL A  33
ILE A  26
 None
 1.07A 3cyxA-3f6rA:
undetectable		 3cyxA-3f6rA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 11 ALA A 141
ASP A 143
ILE A 120
VAL A  33
ILE A  26
 None
 0.94A 3em4U-3f6rA:
undetectable		 3em4U-3f6rA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 9 ALA A 141
ASP A 143
ILE A 120
VAL A  33
ILE A  26
 None
 0.96A 3ndwB-3f6rA:
undetectable		 3ndwB-3f6rA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 11 ALA A 141
ASP A 143
ILE A 120
VAL A  33
ILE A  26
 None
 0.97A 3oxxD-3f6rA:
undetectable		 3oxxD-3f6rA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 ALA A 141
ASP A 143
ILE A 120
VAL A  33
ILE A  26
 None
 0.98A 3pwrA-3f6rA:
undetectable		 3pwrA-3f6rA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  22
PHE A 140
ILE A   6
GLY A  56
VAL A  88
 None
 1.10A 4nkvA-3f6rA:
undetectable		 4nkvA-3f6rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  22
PHE A 140
ILE A   6
GLY A  56
VAL A  88
 None
 1.08A 4nkvC-3f6rA:
undetectable		 4nkvC-3f6rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  22
PHE A 140
ILE A   6
GLY A  56
VAL A  88
 None
 1.09A 4nkvD-3f6rA:
undetectable		 4nkvD-3f6rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  22
PHE A 140
ILE A   6
GLY A  56
VAL A  88
 None
 1.04A 4nkxC-3f6rA:
undetectable		 4nkxC-3f6rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 LEU A  22
PHE A 140
ILE A   6
GLY A  56
VAL A  88
 None
 1.05A 4nkxD-3f6rA:
undetectable		 4nkxD-3f6rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 MET A  67
ALA A  38
ILE A 108
ILE A  81
TYR A  50
 None
 1.41A 4qe6A-3f6rA:
undetectable		 4qe6A-3f6rA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 149 (-2.9A)
None
None
FMN  A 149 (-3.8A)
FMN  A 149 (-3.7A)
 0.81A 4uciA-3f6rA:
undetectable		 4uciA-3f6rA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 149 (-2.9A)
None
None
FMN  A 149 (-3.8A)
FMN  A 149 (-3.7A)
 0.83A 4uciB-3f6rA:
undetectable		 4uciB-3f6rA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		5 / 12 GLY A  94
GLU A 127
GLY A 128
SER A  93
ALA A  59
 FMN  A 149 (-2.9A)
None
None
FMN  A 149 (-3.8A)
FMN  A 149 (-3.7A)
 0.80A 4uckA-3f6rA:
undetectable		 4uckA-3f6rA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3f6r FLAVODOXIN
(Desulfovibrio
desulfuricans) 		3 / 3 ASP A  40
VAL A   7
LEU A  46
 None
 0.68A 5e5jB-3f6rA:
undetectable		 5e5jB-3f6rA:
19.48