SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 11 LEU A  22
LEU A  23
ALA A  20
HIS A 113
LEU A  13
 None
 1.09A 1g50A-3f7cA:
undetectable		 1g50A-3f7cA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 LEU A  22
LEU A  23
ALA A  20
HIS A 113
LEU A  13
 None
 1.08A 1gwrA-3f7cA:
undetectable		 1gwrA-3f7cA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  22
LEU A  99
LEU A 121
THR A 123
ALA A 122
 None
 0.98A 2egvA-3f7cA:
undetectable		 2egvA-3f7cA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  22
LEU A  99
LEU A 121
THR A 123
ALA A 122
 None
 0.97A 2egvB-3f7cA:
undetectable		 2egvB-3f7cA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A  26
GLU A  27
LEU A  23
LEU A  52
LEU A  75
 None
 1.13A 2jfaA-3f7cA:
undetectable		 2jfaA-3f7cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A  26
GLU A  27
LEU A  23
LEU A  52
LEU A  75
 None
 1.12A 2jfaB-3f7cA:
undetectable		 2jfaB-3f7cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  22
LEU A  23
ALA A  20
HIS A 113
LEU A  13
 None
 1.01A 3olsA-3f7cA:
undetectable		 3olsA-3f7cA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  22
LEU A  23
ALA A  20
HIS A 113
LEU A  13
 None
 1.06A 3q95B-3f7cA:
undetectable		 3q95B-3f7cA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 TYR A  91
GLY A  89
ALA A  87
PHE A 129
SER A 133
 None
 1.37A 3s8pA-3f7cA:
undetectable		 3s8pA-3f7cA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 TYR A  91
GLY A  89
ALA A  87
PHE A 129
SER A 133
 None
 1.38A 3s8pB-3f7cA:
undetectable		 3s8pB-3f7cA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 TYR A  91
GLY A  89
ALA A  87
PHE A 129
SER A 133
 None
 1.35A 4bupB-3f7cA:
undetectable		 4bupB-3f7cA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 LEU A  22
LEU A  23
ALA A  20
HIS A 113
LEU A  13
 None
 1.05A 4pxmA-3f7cA:
undetectable		 4pxmA-3f7cA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_A_15UA301_1
(THROMBIN HEAVY CHAIN)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 10 HIS A 113
LEU A  22
ALA A  20
ALA A 115
GLY A  15
 None
 1.11A 4rn6A-3f7cA:
undetectable		 4rn6A-3f7cA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 127
VAL A 126
ALA A 122
SER A 119
LEU A  25
 None
 1.19A 4rrwB-3f7cA:
undetectable		 4rrwB-3f7cA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 MET A 127
VAL A 126
ALA A 122
SER A 119
LEU A  25
 None
 1.19A 4rrzB-3f7cA:
undetectable		 4rrzB-3f7cA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3f7c PROTEIN OF UNKNOWN
FUNCTION (DUF416)
(Marinobacter
hydrocarbonoclas
ticus) 		5 / 12 ALA A  26
GLU A  27
LEU A  23
LEU A  52
LEU A  75
 None
 1.17A 4xi3D-3f7cA:
undetectable		 4xi3D-3f7cA:
20.16