SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		5 / 12 SER A 234
GLY A 336
GLY A 113
ALA A 330
VAL A 284
 None
 1.08A 1jg4A-3f7mA:
undetectable		 1jg4A-3f7mA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 SER A 118
LEU A 337
TYR A 127
GLY A 380
 None
 1.24A 1liiA-3f7mA:
1.5		 1liiA-3f7mA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_1
(PROTEIN (METHIONINE
REPRESSOR))		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
 None
 1.26A 1mj2B-3f7mA:
undetectable		 1mj2B-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
 None
 1.27A 1mj2D-3f7mA:
undetectable		 1mj2D-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_1
(METHIONINE REPRESSOR)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
 None
 1.24A 1mjoB-3f7mA:
undetectable		 1mjoB-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_0
(METHIONINE REPRESSOR)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
 None
 1.19A 1mjoA-3f7mA:
undetectable		 1mjoA-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_1
(METHIONINE REPRESSOR)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
 None
 1.25A 1mjoD-3f7mA:
undetectable		 1mjoD-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		5 / 12 SER A 236
SER A 234
VAL A 284
GLY A 285
ALA A 263
 None
 1.22A 2x2iC-3f7mA:
undetectable		 2x2iC-3f7mA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 8 VAL A 257
LEU A 252
ILE A 212
VAL A 199
 None
 0.97A 4ma7A-3f7mA:
undetectable		 4ma7A-3f7mA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		4 / 4 VAL A 303
ALA A 262
ILE A 334
THR A 331
 None
 0.95A 5e4dB-3f7mA:
undetectable		 5e4dB-3f7mA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		5 / 12 GLY A 309
LEU A 237
GLY A 264
SER A 297
ASN A 265
 None
 1.16A 5vopB-3f7mA:
undetectable		 5vopB-3f7mA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 3f7m ALKALINE SERINE
PROTEASE VER112
(Lecanicillium
psalliotae) 		5 / 12 PRO A 275
ILE A 212
ASP A 216
ALA A 219
MET A 235
 None
 1.38A 5zovB-3f7mA:
0.0		 5zovB-3f7mA:
20.51