SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 12 ASN A 221
LEU A 219
LEU A 257
MET A 289
MET A 234
 None
EDO  A 294 ( 4.9A)
None
None
None
 1.12A 1a28A-3f7pA:
undetectable		 1a28A-3f7pA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 TYR A 281
TRP A 194
LEU A 257
MET A 289
 None
 1.18A 1uw6A-3f7pA:
undetectable
1uw6B-3f7pA:
undetectable		 1uw6A-3f7pA:
22.80
1uw6B-3f7pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 TYR A 281
TRP A 194
LEU A 257
MET A 289
 None
 1.20A 1uw6D-3f7pA:
undetectable
1uw6E-3f7pA:
undetectable		 1uw6D-3f7pA:
22.80
1uw6E-3f7pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 TYR A 281
TRP A 194
LEU A 257
MET A 289
 None
 1.20A 1uw6G-3f7pA:
undetectable
1uw6H-3f7pA:
undetectable		 1uw6G-3f7pA:
22.80
1uw6H-3f7pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 TYR A 281
TRP A 194
LEU A 257
MET A 289
 None
 1.19A 1uw6P-3f7pA:
undetectable
1uw6Q-3f7pA:
undetectable		 1uw6P-3f7pA:
22.80
1uw6Q-3f7pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 TRP A 194
LEU A 257
MET A 289
TYR A 281
 None
 1.16A 1uw6P-3f7pA:
undetectable
1uw6T-3f7pA:
undetectable		 1uw6P-3f7pA:
22.80
1uw6T-3f7pA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 8 ARG A  69
ASP A 269
LEU A 243
ASP A 216
GLU A  66
 None
None
None
EDO  A 294 (-3.6A)
None
 1.48A 2zw9A-3f7pA:
undetectable		 2zw9A-3f7pA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 12 ILE A 147
ILE A 152
GLY A 100
LEU A 106
LEU A 137
 None
 1.08A 3em0B-3f7pA:
undetectable		 3em0B-3f7pA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3f7p PLECTIN-1
(Homo
sapiens) 		3 / 3 MET A 185
GLU A 189
LEU A 193
 None
 0.44A 4v2oB-3f7pA:
undetectable		 4v2oB-3f7pA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 ARG A  69
VAL A  70
ASP A 264
ASP A 267
 None
 0.85A 4xqgA-3f7pA:
undetectable		 4xqgA-3f7pA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3f7p PLECTIN-1
(Homo
sapiens) 		4 / 8 ARG A  69
VAL A  70
ASP A 264
ASP A 267
 None
 0.84A 4xqgB-3f7pA:
undetectable		 4xqgB-3f7pA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3f7p PLECTIN-1
(Homo
sapiens) 		3 / 3 ASN A 209
ASP A 216
GLY A 217
 None
EDO  A 294 (-3.6A)
None
 0.64A 5fctB-3f7pA:
undetectable		 5fctB-3f7pA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 164
ILE A 168
LEU A 169
ILE A 152
ASN A 156
 None
 1.36A 5vkqA-3f7pA:
undetectable
5vkqD-3f7pA:
undetectable		 5vkqA-3f7pA:
10.99
5vkqD-3f7pA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 152
ASN A 156
ILE A 164
ILE A 168
LEU A 169
 None
 1.37A 5vkqA-3f7pA:
undetectable
5vkqB-3f7pA:
undetectable		 5vkqA-3f7pA:
10.99
5vkqB-3f7pA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3f7p PLECTIN-1
(Homo
sapiens) 		5 / 10 ILE A 152
ASN A 156
ILE A 164
ILE A 168
LEU A 169
 None
 1.36A 5vkqC-3f7pA:
undetectable
5vkqD-3f7pA:
undetectable		 5vkqC-3f7pA:
10.99
5vkqD-3f7pA:
10.99