SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		4 / 7 SER A1221
PRO A1220
TYR A1253
ALA A1244
 None
 0.93A 1k5qA-3f7qA:
undetectable
1k5qB-3f7qA:
undetectable		 1k5qA-3f7qA:
19.07
1k5qB-3f7qA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		4 / 8 ILE A1326
SER A1325
SER A1232
LEU A1284
 None
 0.78A 2cdqA-3f7qA:
undetectable		 2cdqA-3f7qA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		4 / 6 PRO A1154
MET A1155
ASP A1175
TYR A1157
 None
 1.10A 2lh8A-3f7qA:
undetectable		 2lh8A-3f7qA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		3 / 3 GLU A1254
VAL A1273
CYH A1256
 1PE  A 703 (-3.1A)
None
None
 0.99A 3fbxA-3f7qA:
undetectable		 3fbxA-3f7qA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		4 / 6 PHE A1228
TYR A1296
THR A1236
VAL A1230
 None
 1.32A 3lb3B-3f7qA:
undetectable		 3lb3B-3f7qA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3f7q INTEGRIN BETA-4
(Homo
sapiens) 		5 / 10 VAL A1273
VAL A1275
TRP A1240
LEU A1226
LEU A1238
 None
 1.40A 4jtqA-3f7qA:
undetectable		 4jtqA-3f7qA:
22.87