SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_2 (PROTEASE)	3f7s	UNCHARACTERIZED NTF2-LIKE PROTEIN (Pseudomonas putida)	4 / 7	LEU A 12 ALA A 86 TRP A 117 ILE A 9	None	0.96A	3wsjB-3f7sA: undetectable	3wsjB-3f7sA: 19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZOD_A_HQEA1173_1 (FMN-BINDING PROTEIN)	3f7s	UNCHARACTERIZED NTF2-LIKE PROTEIN (Pseudomonas putida)	4 / 7	TYR A 53 ASP A 40 TRP A 124 HIS A 56	None UNL A 142 (-3.1A) UNL A 142 ( 4.4A) None	1.30A	3zodA-3f7sA: undetectable	3zodA-3f7sA: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_A_1N1A601_2 (TYROSINE-PROTEIN KINASE ABL1)	3f7s	UNCHARACTERIZED NTF2-LIKE PROTEIN (Pseudomonas putida)	3 / 3	MET A 104 ASP A 40 PHE A 39	UNL A 142 ( 4.9A) UNL A 142 (-3.1A) None	1.06A	4xeyA-3f7sA: undetectable	4xeyA-3f7sA: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XEY_B_1N1B601_2 (TYROSINE-PROTEIN KINASE ABL1)	3f7s	UNCHARACTERIZED NTF2-LIKE PROTEIN (Pseudomonas putida)	3 / 3	MET A 104 ASP A 40 PHE A 39	UNL A 142 ( 4.9A) UNL A 142 (-3.1A) None	1.02A	4xeyB-3f7sA: undetectable	4xeyB-3f7sA: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JO9_A_SORA302_0 (RIBITOL 2-DEHYDROGENASE)	3f7s	UNCHARACTERIZED NTF2-LIKE PROTEIN (Pseudomonas putida)	5 / 12	TYR A 53 TRP A 124 GLU A 122 TRP A 57 PHE A 70	None UNL A 142 ( 4.4A) None UNL A 142 (-4.0A) None	1.16A	5jo9A-3f7sA: undetectable	5jo9A-3f7sA: 19.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3WSJ_A_MK1A201_2","PROTEASE;PROTEASE","3f7s","UNCHARACTERIZED NTF2-LIKE PROTEIN","Pseudomonas putida",4,"LEU A  12;ALA A  86;TRP A 117;ILE A   9","None","0.96A","3wsjB-3f7sA:undetectable","3wsjB-3f7sA:19.18"],["3ZOD_A_HQEA1173_1","FMN-BINDING PROTEIN","3f7s","UNCHARACTERIZED NTF2-LIKE PROTEIN","Pseudomonas putida",4,"TYR A  53;ASP A  40;TRP A 124;HIS A  56","None;UNL A 142 (-3.1A);UNL A 142 ( 4.4A);None","1.30A","3zodA-3f7sA:undetectable","3zodA-3f7sA:21.03"],["4XEY_A_1N1A601_2","TYROSINE-PROTEIN KINASE ABL1","3f7s","UNCHARACTERIZED NTF2-LIKE PROTEIN","Pseudomonas putida",3,"MET A 104;ASP A  40;PHE A  39","UNL A 142 ( 4.9A);UNL A 142 (-3.1A);None","1.06A","4xeyA-3f7sA:undetectable","4xeyA-3f7sA:16.13"],["4XEY_B_1N1B601_2","TYROSINE-PROTEIN KINASE ABL1","3f7s","UNCHARACTERIZED NTF2-LIKE PROTEIN","Pseudomonas putida",3,"MET A 104;ASP A  40;PHE A  39","UNL A 142 ( 4.9A);UNL A 142 (-3.1A);None","1.02A","4xeyB-3f7sA:undetectable","4xeyB-3f7sA:16.13"],["5JO9_A_SORA302_0","RIBITOL 2-DEHYDROGENASE","3f7s","UNCHARACTERIZED NTF2-LIKE PROTEIN","Pseudomonas putida",5,"TYR A  53;TRP A 124;GLU A 122;TRP A  57;PHE A  70","None;UNL A 142 ( 4.4A);None;UNL A 142 (-4.0A);None","1.16A","5jo9A-3f7sA:undetectable","5jo9A-3f7sA:19.83"]]