SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f7w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 9 HIS A 179
LEU A 180
ALA A 284
LEU A 256
LEU A 259
 None
 1.45A 1hwiA-3f7wA:
undetectable		 1hwiA-3f7wA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		3 / 3 THR A  85
GLU A  60
ASP A 193
 None
EDO  A 293 (-3.5A)
None
 0.84A 1nt2A-3f7wA:
undetectable		 1nt2A-3f7wA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		3 / 3 GLU A 219
HIS A 257
HIS A 217
 None
 0.57A 1oe2A-3f7wA:
undetectable		 1oe2A-3f7wA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 10 ASP A 124
TRP A 123
GLY A 215
GLY A 120
SER A 118
 PEG  A 296 ( 4.3A)
None
None
None
None
 1.22A 1w76B-3f7wA:
undetectable		 1w76B-3f7wA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 6 ARG A  58
GLU A  60
PRO A 211
ALA A 213
 None
EDO  A 293 (-3.5A)
None
None
 1.39A 2ejfB-3f7wA:
undetectable		 2ejfB-3f7wA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 5 LEU A 225
VAL A 173
LEU A 180
ARG A 282
 None
 1.12A 2oiqA-3f7wA:
7.6		 2oiqA-3f7wA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		6 / 12 GLY A 192
GLY A 128
LEU A  67
GLU A  60
ILE A 190
HIS A 112
 None
None
None
EDO  A 293 (-3.5A)
None
None
 1.34A 2oxtC-3f7wA:
undetectable		 2oxtC-3f7wA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 10 GLU A 117
GLY A 216
ALA A 220
LEU A  67
ARG A  69
 None
 1.40A 3a3yA-3f7wA:
undetectable		 3a3yA-3f7wA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 9 LEU A 225
MET A 111
GLN A 107
PHE A 104
VAL A 236
 None
 1.48A 3jwqA-3f7wA:
undetectable		 3jwqA-3f7wA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 236
LEU A 225
ALA A 110
GLY A 205
ALA A 206
 None
 1.04A 3ln1A-3f7wA:
undetectable		 3ln1A-3f7wA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 236
LEU A 225
ALA A 110
GLY A 205
ALA A 206
 None
 1.04A 3ln1B-3f7wA:
undetectable		 3ln1B-3f7wA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 236
LEU A 225
ALA A 110
GLY A 205
ALA A 206
 None
 1.03A 3ln1C-3f7wA:
undetectable		 3ln1C-3f7wA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 236
LEU A 225
ALA A 110
GLY A 205
ALA A 206
 None
 1.03A 3ln1D-3f7wA:
undetectable		 3ln1D-3f7wA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 7 LEU A 230
VAL A 199
LEU A 246
ASP A 221
 None
 0.85A 3rgfA-3f7wA:
5.5		 3rgfA-3f7wA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 7 LEU A 230
VAL A 236
VAL A 199
ASP A 221
 None
 0.90A 3rgfA-3f7wA:
5.5		 3rgfA-3f7wA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 6 LEU A  41
ASP A  82
LEU A  11
THR A  12
 None
 1.09A 3rozA-3f7wA:
undetectable		 3rozA-3f7wA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 7 ASN A   2
ALA A  45
ARG A  27
ALA A  50
 None
 0.99A 3twpB-3f7wA:
undetectable		 3twpB-3f7wA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 7 ASN A   2
ALA A  45
ARG A  27
ALA A  50
 None
 1.10A 3twpC-3f7wA:
undetectable		 3twpC-3f7wA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 10 LYS A  44
PRO A  76
LEU A 200
ILE A 209
ASP A 210
 EDO  A 293 (-3.0A)
None
None
UNL  A 288 (-3.6A)
None
 0.78A 4dtaA-3f7wA:
16.6		 4dtaA-3f7wA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 5 LEU A  53
TYR A 126
LEU A 130
ARG A 155
 None
PEG  A 296 ( 4.1A)
None
None
 1.38A 4em2A-3f7wA:
undetectable		 4em2A-3f7wA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 VAL A 236
LEU A 225
ALA A 110
GLY A 205
ALA A 206
 None
 0.99A 5jw1A-3f7wA:
undetectable		 5jw1A-3f7wA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		4 / 7 LEU A  86
SER A  25
ILE A 127
ASP A 210
 None
 0.99A 5n5dA-3f7wA:
undetectable		 5n5dA-3f7wA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 LEU A  67
GLY A 115
ALA A 114
PRO A  74
VAL A  75
 None
EDO  A 295 (-3.5A)
None
None
None
 0.90A 6difB-3f7wA:
undetectable		 6difB-3f7wA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3f7w PUTATIVE
FRUCTOSAMINE-3-KINAS
E
(Thermobifida
fusca) 		5 / 12 LEU A  67
GLY A 115
ALA A 114
PRO A  74
VAL A  75
 None
EDO  A 295 (-3.5A)
None
None
None
 0.76A 6dilB-3f7wA:
undetectable		 6dilB-3f7wA:
15.58