SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 10 VAL A  69
VAL A 105
VAL A  16
ILE A 143
VAL A 145
 None
 1.34A 2qboA-3f84A:
undetectable		 2qboA-3f84A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 10 VAL A 220
VAL A 256
VAL A 167
ILE A 294
VAL A 296
 None
 1.32A 2qboA-3f84A:
undetectable		 2qboA-3f84A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 12 LEU A 283
ASP A  57
VAL A  63
ASN A  60
ASP A 286
 None
 1.04A 2x2iB-3f84A:
undetectable		 2x2iB-3f84A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 12 THR A  34
LEU A  12
VAL A  16
ILE A  67
LEU A 128
 None
 1.10A 3ijdA-3f84A:
undetectable		 3ijdA-3f84A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 12 THR A 185
LEU A 163
VAL A 167
ILE A 218
LEU A 279
 None
 1.01A 3ijdA-3f84A:
undetectable		 3ijdA-3f84A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 12 GLY A 120
ASP A  57
LEU A  59
ASN A  60
ASN A 190
 None
 1.21A 3q87B-3f84A:
undetectable		 3q87B-3f84A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		4 / 8 VAL A  69
VAL A 126
ILE A 143
LEU A   4
 None
 0.90A 4jq1B-3f84A:
undetectable		 4jq1B-3f84A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		4 / 8 VAL A 220
VAL A 277
ILE A 294
LEU A 155
 None
 0.93A 4jq1B-3f84A:
undetectable		 4jq1B-3f84A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 12 LEU A   4
VAL A  47
VAL A  45
LEU A  88
PHE A  83
 None
 0.93A 4y0qA-3f84A:
undetectable		 4y0qA-3f84A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3f84 CFA/I FIMBRIAL
SUBUNIT B
(Escherichia
coli) 		5 / 10 LEU A  76
VAL A  75
LEU A 128
GLU A 103
ILE A 106
 None
 1.13A 5v02B-3f84A:
undetectable
5v02R-3f84A:
undetectable		 5v02B-3f84A:
17.89
5v02R-3f84A:
20.40