SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		4 / 6 VAL A 110
GLY A  75
LEU A  71
GLU A 100
 None
 0.90A 1fduD-3f8kA:
undetectable		 1fduD-3f8kA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		5 / 11 LEU A  71
SER A  78
PHE A  77
LEU A  79
THR A 109
 None
COA  A 301 (-3.4A)
None
COA  A 301 (-4.4A)
None
 1.32A 1mmtA-3f8kA:
undetectable		 1mmtA-3f8kA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		5 / 12 TYR A 113
ILE A 122
GLY A 125
ILE A 124
GLY A  75
 None
None
None
COA  A 301 (-4.6A)
None
 0.95A 5d4uC-3f8kA:
undetectable		 5d4uC-3f8kA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		5 / 12 TYR A 113
ILE A 122
GLY A 125
ILE A 124
GLY A  75
 None
None
None
COA  A 301 (-4.6A)
None
 1.00A 5d4uD-3f8kA:
undetectable		 5d4uD-3f8kA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  21
LEU A  25
PHE A  34
THR A  56
ALA A  69
 None
 1.22A 5ieoA-3f8kA:
undetectable		 5ieoA-3f8kA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3f8k PROTEIN
ACETYLTRANSFERASE
(Sulfolobus
solfataricus) 		5 / 12 LEU A  21
LEU A  25
PHE A  34
THR A  56
ALA A  69
 None
 1.19A 5iepA-3f8kA:
undetectable		 5iepA-3f8kA:
25.60