SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XL6_B_SPMB3001_1 (INWARD RECTIFIER POTASSIUM CHANNEL)	3f8m	GNTR-FAMILY PROTEIN TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	4 / 5	ALA A 165 TYR A 164 ALA A 161 GLN A 78	None	0.96A	1xl6A-3f8mA: undetectable 1xl6B-3f8mA: undetectable	1xl6A-3f8mA: 21.86 1xl6B-3f8mA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q72_A_IXXA801_1 (TRANSPORTER)	3f8m	GNTR-FAMILY PROTEIN TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	5 / 11	LEU A 127 ARG A 154 ALA A 102 LEU A 106 ASP A 105	None	1.22A	2q72A-3f8mA: undetectable	2q72A-3f8mA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_A_CQAA302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	3f8m	GNTR-FAMILY PROTEIN TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	4 / 7	GLU A 87 TYR A 164 ARG A 220 GLY A 81	None	1.04A	4fgzA-3f8mA: undetectable	4fgzA-3f8mA: 20.14