SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 ASP A 104
HIS A  93
HIS A  91
 MN  A 201 (-2.3A)
MN  A 201 (-3.2A)
MN  A 201 (-3.2A)
 0.65A 1oe1A-3f8nA:
undetectable		 1oe1A-3f8nA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 ASP A 104
HIS A  93
HIS A  91
 MN  A 201 (-2.3A)
MN  A 201 (-3.2A)
MN  A 201 (-3.2A)
 0.64A 1oe3A-3f8nA:
undetectable		 1oe3A-3f8nA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		4 / 8 ASP A 104
ASP A  85
LEU A  75
HIS A  91
 MN  A 201 (-2.3A)
MN  A 201 (-2.9A)
None
MN  A 201 (-3.2A)
 0.81A 2q0iA-3f8nA:
undetectable		 2q0iA-3f8nA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 ASP A 104
HIS A  93
HIS A  91
 MN  A 201 (-2.3A)
MN  A 201 (-3.2A)
MN  A 201 (-3.2A)
 0.66A 2xxgA-3f8nA:
undetectable		 2xxgA-3f8nA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 ASP A 104
HIS A  93
HIS A  91
 MN  A 201 (-2.3A)
MN  A 201 (-3.2A)
MN  A 201 (-3.2A)
 0.69A 2xxgC-3f8nA:
undetectable		 2xxgC-3f8nA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BCS_A_ACTA1126_0
(CHIMERIC AVIDIN)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		4 / 4 THR A  58
GLN A  23
ARG A  24
THR A  21
 None
 1.19A 4bcsA-3f8nA:
0.0		 4bcsA-3f8nA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 HIS A  91
ASP A  85
HIS A  37
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.6A)
 0.78A 5oexA-3f8nA:
undetectable		 5oexA-3f8nA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 HIS A  91
ASP A  85
HIS A  37
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.6A)
 0.69A 5oexB-3f8nA:
undetectable		 5oexB-3f8nA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 HIS A  91
ASP A  85
HIS A  37
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.6A)
 0.68A 5oexC-3f8nA:
undetectable		 5oexC-3f8nA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3f8n PEROXIDE OPERON
REGULATOR
(Bacillus
subtilis) 		3 / 3 HIS A  91
ASP A  85
HIS A  37
 MN  A 201 (-3.2A)
MN  A 201 (-2.9A)
MN  A 201 (-3.6A)
 0.67A 5oexD-3f8nA:
undetectable		 5oexD-3f8nA:
15.32