SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f92'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K
(Homo
sapiens) 		4 / 8 LEU A 106
GLU A  15
ILE A   9
TYR A  66
 None
 1.03A 1qvtA-3f92A:
undetectable		 1qvtA-3f92A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K
(Homo
sapiens) 		5 / 11 ALA A 145
ILE A  79
ALA A 153
PRO A  50
PHE A 141
 None
 1.24A 2admA-3f92A:
undetectable		 2admA-3f92A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K
(Homo
sapiens) 		5 / 12 VAL A  16
LEU A 106
VAL A 109
THR A  77
VAL A  73
 None
 0.80A 2cbrA-3f92A:
undetectable		 2cbrA-3f92A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K
(Homo
sapiens) 		4 / 8 TYR A  66
THR A 108
VAL A  29
ILE A  60
 None
 0.94A 2qbmA-3f92A:
undetectable		 2qbmA-3f92A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3f92 UBIQUITIN-CONJUGATIN
G ENZYME E2 K
(Homo
sapiens) 		4 / 5 LEU A 110
ARG A  74
ILE A  84
PHE A  75
 None
 1.30A 3ln1D-3f92A:
undetectable		 3ln1D-3f92A:
17.52