SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.81A 2bfpA-3f95A:
undetectable		 2bfpA-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.98A 2bfpA-3f95A:
undetectable		 2bfpA-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.83A 2bfpB-3f95A:
undetectable		 2bfpB-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.96A 2bfpB-3f95A:
undetectable		 2bfpB-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.81A 2bfpC-3f95A:
undetectable		 2bfpC-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 SER A 749
PHE A 747
LEU A 791
LEU A 782
 None
 0.80A 2bfpD-3f95A:
undetectable		 2bfpD-3f95A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 8 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.40A 2einA-3f95A:
undetectable
2einJ-3f95A:
undetectable		 2einA-3f95A:
17.88
2einJ-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		3 / 3 LEU A 718
LEU A 642
MET A 646
 None
 0.83A 2itzA-3f95A:
undetectable		 2itzA-3f95A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 PHE A 750
ARG A 783
LEU A 798
LEU A 716
ILE A 778
 None
 1.16A 2v0mC-3f95A:
undetectable		 2v0mC-3f95A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 8 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.49A 3abkA-3f95A:
undetectable
3abkJ-3f95A:
undetectable		 3abkA-3f95A:
17.88
3abkJ-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 ILE A 784
PHE A 747
ARG A 721
LEU A 718
 None
 0.87A 3ablN-3f95A:
undetectable
3ablW-3f95A:
undetectable		 3ablN-3f95A:
17.88
3ablW-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 8 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.43A 3abmN-3f95A:
undetectable
3abmW-3f95A:
undetectable		 3abmN-3f95A:
17.88
3abmW-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 8 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.44A 3asoN-3f95A:
undetectable
3asoW-3f95A:
undetectable		 3asoN-3f95A:
17.88
3asoW-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ARG A 743
GLN A 733
LEU A 798
LEU A 707
ILE A 778
 None
 1.04A 3gwxB-3f95A:
undetectable		 3gwxB-3f95A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 LEU A 716
ALA A 763
GLY A 714
SER A 808
LEU A 809
 None
 1.26A 3gyqA-3f95A:
undetectable
3gyqB-3f95A:
undetectable		 3gyqA-3f95A:
21.35
3gyqB-3f95A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 10 LEU A 782
LEU A 732
SER A 790
LEU A 791
LEU A 762
 None
 1.17A 4yiaA-3f95A:
undetectable		 4yiaA-3f95A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 7 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.45A 5b3sN-3f95A:
undetectable
5b3sW-3f95A:
undetectable		 5b3sN-3f95A:
17.88
5b3sW-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 7 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.33A 5iy5N-3f95A:
undetectable
5iy5W-3f95A:
undetectable		 5iy5N-3f95A:
17.88
5iy5W-3f95A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		4 / 8 LEU A 762
MET A 754
LEU A 791
ILE A 784
 None
 0.97A 5mzjA-3f95A:
undetectable		 5mzjA-3f95A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 LEU A 718
ILE A 793
LEU A 716
LEU A 798
LEU A 637
 None
 0.91A 5nfjA-3f95A:
undetectable		 5nfjA-3f95A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 8 ILE A 784
PHE A 747
ARG A 721
MET A 720
LEU A 718
 None
 1.46A 5zcpN-3f95A:
undetectable
5zcpW-3f95A:
undetectable		 5zcpN-3f95A:
17.88
5zcpW-3f95A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ILE A 722
ALA A 755
GLN A 752
ILE A 784
LEU A 762
 None
 1.02A 6a60D-3f95A:
undetectable		 6a60D-3f95A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ASP A 685
LEU A 650
LEU A 673
ALA A 663
LEU A 642
 None
 1.01A 6ew0B-3f95A:
undetectable		 6ew0B-3f95A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ASP A 685
LEU A 650
LEU A 673
ALA A 663
LEU A 642
 None
 1.01A 6ew0D-3f95A:
undetectable		 6ew0D-3f95A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ASP A 685
LEU A 650
LEU A 673
ALA A 663
LEU A 642
 None
 1.01A 6ew0H-3f95A:
undetectable		 6ew0H-3f95A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3f95 BETA-GLUCOSIDASE
(Pseudoalteromona
s
sp.
BB1) 		5 / 12 ASP A 685
LEU A 650
LEU A 673
ALA A 663
LEU A 642
 None
 1.01A 6ew0I-3f95A:
undetectable		 6ew0I-3f95A:
24.51