SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 LEU A  50
LEU A  46
ILE A  11
ILE A  22
ALA A  21
 None
 0.97A 2bxcA-3f9iA:
undetectable		 2bxcA-3f9iA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		4 / 4 LEU A  46
ILE A  11
ILE A  22
ALA A  21
 None
 0.89A 2i30A-3f9iA:
undetectable		 2i30A-3f9iA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 ILE A  71
ILE A 133
ILE A  22
THR A  12
LEU A  61
 None
 1.16A 2rlcA-3f9iA:
undetectable		 2rlcA-3f9iA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 9 GLY A 179
VAL A 137
ILE A  18
VAL A 212
VAL A 176
 None
 1.29A 3fi0K-3f9iA:
undetectable		 3fi0K-3f9iA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		3 / 3 ASP A 101
LYS A 102
ASP A 105
 None
 0.48A 4a7tA-3f9iA:
undetectable		 4a7tA-3f9iA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 11 ILE A  22
ILE A  18
GLY A  17
VAL A 234
GLY A 207
 None
 1.03A 4ac9B-3f9iA:
7.1
4ac9C-3f9iA:
6.9		 4ac9B-3f9iA:
24.06
4ac9C-3f9iA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 GLY A 138
GLY A 144
ILE A 201
THR A 205
GLY A 179
 None
 0.94A 4n48A-3f9iA:
6.8		 4n48A-3f9iA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 GLY A 141
GLY A 144
ILE A 201
THR A 205
GLY A 179
 None
 1.29A 4n48A-3f9iA:
6.8		 4n48A-3f9iA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 GLY A 138
GLY A 144
ILE A 201
THR A 205
GLY A 179
 None
 0.95A 4n48B-3f9iA:
6.7		 4n48B-3f9iA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		4 / 7 LEU A 114
ASN A 115
LEU A  10
ILE A 171
 None
 1.01A 4okwA-3f9iA:
undetectable		 4okwA-3f9iA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		4 / 6 ILE A 181
PRO A 209
ILE A  11
VAL A  81
 None
 0.95A 4zj8A-3f9iA:
6.0		 4zj8A-3f9iA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE
(Rickettsia
prowazekii) 		5 / 12 LEU A 114
LEU A  70
ILE A  11
ALA A  14
ILE A  34
 None
 1.26A 5eypB-3f9iA:
7.3		 5eypB-3f9iA:
22.15