SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3faw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ASP A 573
PHE A 667
VAL A 577
 None
 0.74A 1kijB-3fawA:
undetectable		 1kijB-3fawA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 8 ASP A1079
ASN A1099
ILE A1148
GLY A1073
 None
 0.71A 1me7A-3fawA:
4.9		 1me7A-3fawA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 8 ASP A1079
ASN A1099
ILE A1148
GLY A1073
 None
 0.75A 1meiA-3fawA:
undetectable		 1meiA-3fawA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		7 / 12 TYR A 691
HIS A 739
PHE A 767
ARG A 800
ASP A 802
GLU A 831
HIS A 918
 None
 0.99A 1mxdA-3fawA:
18.5		 1mxdA-3fawA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		6 / 12 ALA A 847
ASP A 848
GLY A 830
ILE A 829
ALA A 815
ILE A 812
 None
 1.42A 1rl8A-3fawA:
undetectable		 1rl8A-3fawA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		6 / 12 ALA A 847
ASP A 848
GLY A 830
ILE A 829
ALA A 815
ILE A 812
 None
 1.43A 1rl8B-3fawA:
undetectable		 1rl8B-3fawA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 VAL A 782
LEU A 549
LEU A 562
ALA A 566
ALA A 482
 None
 1.09A 1sa1C-3fawA:
undetectable
1sa1D-3fawA:
undetectable		 1sa1C-3fawA:
19.67
1sa1D-3fawA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A1066
GLN A 887
ASN A 895
LEU A 869
VAL A1098
 None
 1.15A 1u72A-3fawA:
undetectable		 1u72A-3fawA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 HIS A 807
ASP A 839
ASN A 758
 None
 0.81A 1wg8B-3fawA:
undetectable		 1wg8B-3fawA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A 717
ILE A 721
ILE A 724
ARG A 727
LEU A 733
 None
 1.01A 1xdkF-3fawA:
undetectable		 1xdkF-3fawA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 SER A 568
GLU A 571
ASP A 511
 None
 0.76A 2avdB-3fawA:
undetectable		 2avdB-3fawA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 THR A 955
LEU A1066
VAL A1107
ALA A1153
VAL A1081
 None
 1.22A 2g72A-3fawA:
undetectable		 2g72A-3fawA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 THR A 955
ILE A1067
VAL A1107
ALA A1153
VAL A1081
 None
 1.30A 2g72B-3fawA:
undetectable		 2g72B-3fawA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 ASN A 590
VAL A 589
TYR A 548
ASN A 479
ALA A 566
 None
 1.23A 2iyfA-3fawA:
undetectable		 2iyfA-3fawA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ASN A 590
VAL A 589
TYR A 548
ASN A 479
ALA A 566
 None
 1.24A 2iyfB-3fawA:
undetectable		 2iyfB-3fawA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		6 / 12 ALA A 847
ASP A 848
GLY A 830
ILE A 829
ALA A 815
ILE A 812
 None
 1.47A 2rkfB-3fawA:
undetectable		 2rkfB-3fawA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 ALA A 388
LEU A 385
ILE A 441
ILE A 411
THR A 463
 None
 1.10A 2w9sC-3fawA:
undetectable		 2w9sC-3fawA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 946
GLN A1036
THR A1035
THR A 922
 None
None
None
CL  A1223 (-4.3A)
 1.33A 2zj0B-3fawA:
undetectable		 2zj0B-3fawA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 946
GLN A1036
THR A1035
THR A 922
 None
None
None
CL  A1223 (-4.3A)
 1.35A 2zj0C-3fawA:
undetectable		 2zj0C-3fawA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 LEU A 946
GLN A1036
THR A1035
THR A 922
 None
None
None
CL  A1223 (-4.3A)
 1.36A 2zj0D-3fawA:
undetectable		 2zj0D-3fawA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 GLY A 859
ILE A 829
ILE A 827
ASP A 910
 None
None
None
CA  A   4 (-2.3A)
 0.83A 3a7eA-3fawA:
undetectable		 3a7eA-3fawA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.55A 3aicA-3fawA:
2.6		 3aicA-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.58A 3aicB-3fawA:
8.7		 3aicB-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		6 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
TYR A 691
 None
 0.59A 3aicC-3fawA:
4.7		 3aicC-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.59A 3aicD-3fawA:
8.8		 3aicD-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.55A 3aicE-3fawA:
4.5		 3aicE-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.60A 3aicF-3fawA:
3.4		 3aicF-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.61A 3aicG-3fawA:
2.7		 3aicG-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.56A 3aicH-3fawA:
2.6		 3aicH-3fawA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A 946
GLN A1036
THR A1035
THR A 922
 None
None
None
CL  A1223 (-4.3A)
 1.34A 3ce6B-3fawA:
undetectable		 3ce6B-3fawA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 THR A 519
THR A 520
THR A 504
GLU A 551
LEU A 534
 None
 1.20A 3gwxB-3fawA:
undetectable		 3gwxB-3fawA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 LEU A 699
ALA A 712
LYS A 706
ILE A 714
SER A 568
 None
CL  A1225 (-3.5A)
None
None
None
 1.34A 3gyqA-3fawA:
undetectable
3gyqB-3fawA:
2.4		 3gyqA-3fawA:
17.76
3gyqB-3fawA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_A_DX4A270_0
(PTERIDINE REDUCTASE
1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 SER A1048
ASP A1092
TYR A1094
PRO A1132
 None
 1.32A 3jqaA-3fawA:
undetectable		 3jqaA-3fawA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_B_DX4B270_0
(PTERIDINE REDUCTASE
1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 SER A1048
ASP A1092
TYR A1094
PRO A1132
 None
 1.37A 3jqaB-3fawA:
undetectable		 3jqaB-3fawA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 SER A1048
ASP A1092
TYR A1094
PRO A1132
 None
 1.32A 3jqaC-3fawA:
undetectable		 3jqaC-3fawA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_D_DX4D270_0
(PTERIDINE REDUCTASE
1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 SER A1048
ASP A1092
TYR A1094
PRO A1132
 None
 1.31A 3jqaD-3fawA:
2.0		 3jqaD-3fawA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 ASN A 920
ASP A1007
ARG A 771
 CL  A1226 (-4.0A)
None
None
 0.91A 3k13A-3fawA:
4.5		 3k13A-3fawA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ASP A 906
ASP A 910
PRO A 908
GLN A 957
 CA  A   4 (-3.0A)
CA  A   4 (-2.3A)
None
None
 1.07A 3l2vA-3fawA:
2.0		 3l2vA-3fawA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 HIS A 943
ILE A 942
HIS A 924
LEU A 946
 CL  A   5 ( 4.8A)
CL  A   5 ( 4.9A)
CL  A   5 (-4.0A)
None
 1.22A 3qpkA-3fawA:
2.0		 3qpkA-3fawA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.16A 3w9tA-3fawA:
undetectable		 3w9tA-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.16A 3w9tB-3fawA:
undetectable		 3w9tB-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.16A 3w9tC-3fawA:
undetectable		 3w9tC-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.15A 3w9tD-3fawA:
undetectable		 3w9tD-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.15A 3w9tE-3fawA:
undetectable		 3w9tE-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.16A 3w9tF-3fawA:
undetectable		 3w9tF-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 VAL A1158
GLY A1159
TYR A1094
ASP A1088
 None
 1.16A 3w9tG-3fawA:
undetectable		 3w9tG-3fawA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ARG A 947
ILE A1031
THR A1035
GLY A 969
 None
CL  A1224 (-3.8A)
None
None
 0.89A 4eq4A-3fawA:
undetectable		 4eq4A-3fawA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 ARG A 947
ILE A1031
THR A1035
GLY A 969
 None
CL  A1224 (-3.8A)
None
None
 0.89A 4eqlA-3fawA:
undetectable		 4eqlA-3fawA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ILE A 533
ALA A 493
LEU A 484
ILE A 540
ASN A 542
 None
 1.11A 4gh8A-3fawA:
undetectable		 4gh8A-3fawA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ILE A 533
ALA A 493
LEU A 484
ILE A 540
ASN A 542
 None
 1.05A 4gh8B-3fawA:
undetectable		 4gh8B-3fawA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 8 PRO A 521
LEU A 538
TYR A 543
LEU A 534
TRP A 530
 None
 1.46A 4jjkA-3fawA:
undetectable		 4jjkA-3fawA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_H_RFPH1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 GLN A 472
GLN A 465
HIS A 451
LEU A 393
ASN A 446
 None
 1.44A 4kmuH-3fawA:
undetectable		 4kmuH-3fawA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 ASN A 590
VAL A 589
TYR A 548
ASN A 479
ALA A 566
 None
 1.22A 4m83A-3fawA:
undetectable		 4m83A-3fawA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 ASN A 590
VAL A 589
TYR A 548
ASN A 479
ALA A 566
 None
 1.25A 4m83B-3fawA:
undetectable		 4m83B-3fawA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 GLY A 891
LEU A 869
MET A 952
THR A1068
ILE A1075
 None
 1.43A 4p6xG-3fawA:
undetectable		 4p6xG-3fawA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 GLY A 891
LEU A 869
MET A 952
THR A1068
ILE A1075
 None
 1.45A 4p6xI-3fawA:
undetectable		 4p6xI-3fawA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ILE A 427
THR A 401
TYR A 456
VAL A 383
LEU A 415
 None
 1.32A 4qynA-3fawA:
undetectable		 4qynA-3fawA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 5 LEU A1045
VAL A1098
TYR A1094
ARG A 866
 None
None
None
CL  A1226 (-4.0A)
 1.11A 4r7iA-3fawA:
undetectable		 4r7iA-3fawA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 9 ALA A 570
ALA A 587
ALA A 566
SER A 695
ALA A 584
 None
 1.27A 4twdA-3fawA:
1.5
4twdB-3fawA:
undetectable
4twdC-3fawA:
1.4
4twdD-3fawA:
2.7
4twdE-3fawA:
undetectable		 4twdA-3fawA:
17.36
4twdB-3fawA:
17.36
4twdC-3fawA:
17.36
4twdD-3fawA:
17.36
4twdE-3fawA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 11 LEU A 439
GLN A 397
ALA A 398
THR A 391
ASP A 392
 None
 1.37A 4uuuA-3fawA:
undetectable
4uuuB-3fawA:
undetectable		 4uuuA-3fawA:
10.21
4uuuB-3fawA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 7 THR A 878
PRO A 879
THR A 883
SER A 871
 None
 1.37A 5b6iA-3fawA:
undetectable		 5b6iA-3fawA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ARG A 800
ASP A 802
GLU A 831
HIS A 918
ASP A 919
 None
 0.93A 5csyB-3fawA:
16.0		 5csyB-3fawA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 ASP A 622
SER A 625
GLN A 627
ALA A 679
TYR A 687
 None
 1.39A 5cxvA-3fawA:
undetectable		 5cxvA-3fawA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 6 ILE A 658
TYR A 616
PHE A1018
THR A1024
 None
 1.37A 5g08A-3fawA:
undetectable		 5g08A-3fawA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 12 THR A1068
GLY A1073
ASP A1144
SER A1145
LEU A1146
 None
 0.92A 5l0zA-3fawA:
undetectable		 5l0zA-3fawA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		5 / 10 GLU A 967
LEU A 717
ALA A 618
SER A 964
THR A 639
 None
 1.34A 5mm4B-3fawA:
undetectable		 5mm4B-3fawA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.66A 5qglA-3fawA:
undetectable		 5qglA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.70A 5qguA-3fawA:
undetectable		 5qguA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.67A 5qgvA-3fawA:
undetectable		 5qgvA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.69A 5qgwA-3fawA:
undetectable		 5qgwA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.67A 5qgxA-3fawA:
undetectable		 5qgxA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.69A 5qh1A-3fawA:
undetectable		 5qh1A-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.69A 5qh4A-3fawA:
undetectable		 5qh4A-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.70A 5qh9A-3fawA:
undetectable		 5qh9A-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.69A 5qhcA-3fawA:
undetectable		 5qhcA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.72A 5qheA-3fawA:
undetectable		 5qheA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.68A 5qhfA-3fawA:
undetectable		 5qhfA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.68A 5qhgA-3fawA:
undetectable		 5qhgA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 VAL A 796
VAL A 731
GLN A 659
 None
 0.68A 5qhhA-3fawA:
undetectable		 5qhhA-3fawA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		4 / 4 TYR A 754
GLY A 481
ASN A 479
ARG A 781
 None
 1.15A 5w7bA-3fawA:
0.0
5w7bC-3fawA:
0.0		 5w7bA-3fawA:
7.48
5w7bC-3fawA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 GLY A 481
ASN A 479
ARG A 781
 None
 0.71A 5w7bD-3fawA:
undetectable		 5w7bD-3fawA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3faw RETICULOCYTE BINDING
PROTEIN
(Streptococcus
agalactiae) 		3 / 3 MET A 702
ASP A 673
ARG A 676
 None
 1.13A 5z6kA-3fawA:
undetectable		 5z6kA-3fawA:
11.82