SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN
(Homo
sapiens) 		5 / 12 HIS A1451
LEU A1367
GLY A1373
ALA A1374
LEU A1378
 None
 1.14A 3n8xA-3fb2A:
undetectable		 3n8xA-3fb2A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_F_ACTF701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN
(Homo
sapiens) 		4 / 4 PHE A1344
HIS A1410
GLY A1402
ILE A1416
 None
 1.41A 4k50E-3fb2A:
1.6		 4k50E-3fb2A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN
(Homo
sapiens) 		3 / 3 VAL A1529
LYS A1537
MET A1540
 None
 0.98A 5nknA-3fb2A:
undetectable		 5nknA-3fb2A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECF_I_DVAI3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3fb2 SPECTRIN ALPHA
CHAIN, BRAIN
SPECTRIN
(Homo
sapiens) 		3 / 3 PHE A1450
ARG A1525
ALA A1457
 None
 0.80A 6ecfB-3fb2A:
undetectable		 6ecfB-3fb2A:
27.33