SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		5 / 12 ILE A  26
ILE A   3
ASN A 209
LEU A 212
LEU A 215
 None
 0.91A 2bdmA-3fb4A:
undetectable		 2bdmA-3fb4A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		4 / 7 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.77A 3bjwB-3fb4A:
undetectable		 3bjwB-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		4 / 7 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.85A 3bjwF-3fb4A:
undetectable		 3bjwF-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		4 / 7 VAL A  90
ILE A  65
GLY A  66
LEU A  45
 None
 0.80A 3bjwH-3fb4A:
undetectable		 3bjwH-3fb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR4_C_AICC401_1
(OUTER MEMBRANE
PROTEIN F)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		4 / 8 ARG A 127
ARG A 160
ASP A  84
ARG A  36
 AP5  A   0 (-2.9A)
AP5  A   0 (-3.3A)
None
AP5  A   0 (-2.8A)
 1.33A 4kr4C-3fb4A:
undetectable		 4kr4C-3fb4A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		5 / 12 GLY A  12
GLN A  16
ALA A  11
VAL A 115
ILE A 208
 AP5  A   0 (-3.4A)
None
AP5  A   0 (-4.4A)
None
None
 1.23A 4pd5A-3fb4A:
undetectable		 4pd5A-3fb4A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		5 / 12 VAL A  59
SER A  30
GLY A  32
ASP A  84
LYS A  13
 AP5  A   0 (-4.0A)
AP5  A   0 ( 4.6A)
AP5  A   0 (-3.6A)
None
AP5  A   0 (-3.1A)
 1.49A 4pevA-3fb4A:
3.8		 4pevA-3fb4A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		5 / 12 VAL A  59
SER A  30
GLY A  32
ASP A  84
LYS A  13
 AP5  A   0 (-4.0A)
AP5  A   0 ( 4.6A)
AP5  A   0 (-3.6A)
None
AP5  A   0 (-3.1A)
 1.44A 4pevC-3fb4A:
undetectable		 4pevC-3fb4A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		3 / 3 LEU A 120
GLN A 117
LYS A  13
 None
None
AP5  A   0 (-3.1A)
 0.75A 6exiB-3fb4A:
undetectable		 6exiB-3fb4A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3fb4 ADENYLATE KINASE
(Jeotgalibacillus
marinus) 		3 / 3 LEU A 120
GLN A 117
LYS A  13
 None
None
AP5  A   0 (-3.1A)
 0.70A 6exiA-3fb4A:
undetectable		 6exiA-3fb4A:
18.10