SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fbs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 1c6yB-3fbsA:
undetectable		 1c6yB-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 1hsgB-3fbsA:
undetectable		 1hsgB-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A  33
VAL A  79
TRP A 230
 FAD  A 298 (-3.5A)
FAD  A 298 (-4.0A)
None
 0.85A 1kqeA-3fbsA:
undetectable
1kqeE-3fbsA:
undetectable		 1kqeA-3fbsA:
10.34
1kqeE-3fbsA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A  33
VAL A  79
TRP A 230
 FAD  A 298 (-3.5A)
FAD  A 298 (-4.0A)
None
 0.86A 1kqeB-3fbsA:
undetectable
1kqeD-3fbsA:
undetectable		 1kqeB-3fbsA:
10.34
1kqeD-3fbsA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 TRP A 230
ALA A  33
VAL A  79
 None
FAD  A 298 (-3.5A)
FAD  A 298 (-4.0A)
 0.85A 1kqeB-3fbsA:
undetectable
1kqeD-3fbsA:
undetectable		 1kqeB-3fbsA:
10.34
1kqeD-3fbsA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 TRP A 230
ALA A  33
VAL A  79
 None
FAD  A 298 (-3.5A)
FAD  A 298 (-4.0A)
 0.86A 1kqeA-3fbsA:
undetectable
1kqeE-3fbsA:
undetectable		 1kqeA-3fbsA:
10.34
1kqeE-3fbsA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 ALA A  33
VAL A  79
TRP A 230
 FAD  A 298 (-3.5A)
FAD  A 298 (-4.0A)
None
 0.88A 1micA-3fbsA:
undetectable
1micB-3fbsA:
undetectable		 1micA-3fbsA:
6.72
1micB-3fbsA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 5 PRO A 251
LYS A 253
MET A 252
ALA A 286
 None
 1.45A 1qhsA-3fbsA:
0.0		 1qhsA-3fbsA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 6 PRO A 251
LYS A 253
MET A 252
ALA A 286
 None
 1.42A 1qhyA-3fbsA:
undetectable		 1qhyA-3fbsA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 1sduB-3fbsA:
undetectable		 1sduB-3fbsA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 ILE A   6
GLY A  10
ALA A  13
VAL A  75
ALA A  33
 None
None
FAD  A 298 (-3.5A)
None
FAD  A 298 (-3.5A)
 1.09A 1sg9C-3fbsA:
3.6		 1sg9C-3fbsA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 10 ILE A  28
LEU A  21
ASP A  32
LEU A  30
ILE A   7
 None
None
FAD  A 298 (-3.0A)
None
None
 1.09A 1yi4A-3fbsA:
undetectable		 1yi4A-3fbsA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.82A 2aquB-3fbsA:
undetectable		 2aquB-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 2avoB-3fbsA:
undetectable		 2avoB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 2avsA-3fbsA:
undetectable		 2avsA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 2avsB-3fbsA:
undetectable		 2avsB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 2avvB-3fbsA:
undetectable		 2avvB-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 2avvE-3fbsA:
undetectable		 2avvE-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 ILE A 105
ARG A 289
GLY A 280
CYH A 263
LEU A  21
 None
 1.37A 2bxeA-3fbsA:
undetectable		 2bxeA-3fbsA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 ILE A 105
CYH A 263
GLY A 280
LEU A  21
SER A 290
 None
 1.22A 2bxeB-3fbsA:
undetectable		 2bxeB-3fbsA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 2fxeB-3fbsA:
undetectable		 2fxeB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.90A 2hs1B-3fbsA:
undetectable		 2hs1B-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 2nmyA-3fbsA:
undetectable		 2nmyA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 2nmzA-3fbsA:
undetectable		 2nmzA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.83A 2nmzB-3fbsA:
undetectable		 2nmzB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 ALA A 267
THR A 249
ALA A 286
ALA A 287
LEU A  30
 None
 1.15A 2nyrA-3fbsA:
3.3		 2nyrA-3fbsA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 2o4kB-3fbsA:
undetectable		 2o4kB-3fbsA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 2o4lB-3fbsA:
undetectable		 2o4lB-3fbsA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.89A 2pymB-3fbsA:
undetectable		 2pymB-3fbsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.91A 2pynB-3fbsA:
undetectable		 2pynB-3fbsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 2q63A-3fbsA:
undetectable		 2q63A-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 2q63B-3fbsA:
undetectable		 2q63B-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 2q64A-3fbsA:
undetectable		 2q64A-3fbsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 2qakA-3fbsA:
undetectable		 2qakA-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.90A 2qakB-3fbsA:
undetectable		 2qakB-3fbsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 2r5pB-3fbsA:
undetectable		 2r5pB-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 2r5pD-3fbsA:
undetectable		 2r5pD-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 10 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.90A 2r5qD-3fbsA:
undetectable		 2r5qD-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 6 ASP A 162
TYR A 137
PHE A 219
LEU A 139
 None
 1.05A 2w98A-3fbsA:
undetectable
2w98B-3fbsA:
3.1		 2w98A-3fbsA:
19.18
2w98B-3fbsA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 8 MET A 108
ALA A 107
GLY A   9
ILE A   8
 None
None
FAD  A 298 (-3.4A)
None
 0.84A 2zm9A-3fbsA:
undetectable		 2zm9A-3fbsA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 3bvbA-3fbsA:
undetectable		 3bvbA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 3cyxA-3fbsA:
undetectable		 3cyxA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.90A 3cyxB-3fbsA:
undetectable		 3cyxB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 3d1xA-3fbsA:
undetectable		 3d1xA-3fbsA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 3d1yA-3fbsA:
undetectable		 3d1yA-3fbsA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.89A 3d1zA-3fbsA:
undetectable		 3d1zA-3fbsA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 3ekqA-3fbsA:
undetectable		 3ekqA-3fbsA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 3ekwB-3fbsA:
undetectable		 3ekwB-3fbsA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 3el1B-3fbsA:
undetectable		 3el1B-3fbsA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.81A 3em4A-3fbsA:
undetectable		 3em4A-3fbsA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 9 ALA A 283
ASP A 279
LEU A  19
VAL A   5
ILE A 105
 None
 1.19A 3em4B-3fbsA:
undetectable		 3em4B-3fbsA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.80A 3em4U-3fbsA:
undetectable		 3em4U-3fbsA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 8 PRO A 269
GLY A 241
PRO A 242
MET A 243
 None
 1.03A 3hcrA-3fbsA:
undetectable		 3hcrA-3fbsA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 SER A  11
ASP A  32
ASP A 265
 FAD  A 298 (-2.6A)
FAD  A 298 (-3.0A)
FAD  A 298 (-3.0A)
 0.70A 3iv6A-3fbsA:
undetectable		 3iv6A-3fbsA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 SER A  11
ASP A  32
ASP A 265
 FAD  A 298 (-2.6A)
FAD  A 298 (-3.0A)
FAD  A 298 (-3.0A)
 0.74A 3iv6C-3fbsA:
undetectable		 3iv6C-3fbsA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.89A 3jvyB-3fbsA:
undetectable		 3jvyB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.81A 3k4vA-3fbsA:
undetectable		 3k4vA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.83A 3k4vD-3fbsA:
undetectable		 3k4vD-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 ARG A 289
GLY A 280
GLY A  14
ALA A 285
ILE A   7
 None
 0.96A 3ku1A-3fbsA:
3.8		 3ku1A-3fbsA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 ARG A 289
GLY A 280
GLY A  14
ALA A 285
ILE A   7
 None
 0.88A 3ku1C-3fbsA:
2.6		 3ku1C-3fbsA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.80A 3ndtA-3fbsA:
undetectable		 3ndtA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 3ndtB-3fbsA:
undetectable		 3ndtB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 3nduA-3fbsA:
undetectable		 3nduA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 3nduB-3fbsA:
undetectable		 3nduB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.83A 3nduD-3fbsA:
undetectable		 3nduD-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 3ndxA-3fbsA:
undetectable		 3ndxA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 3ndxB-3fbsA:
undetectable		 3ndxB-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 3nu5A-3fbsA:
undetectable		 3nu5A-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.86A 3nu5B-3fbsA:
undetectable		 3nu5B-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.81A 3oxxA-3fbsA:
undetectable		 3oxxA-3fbsA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.78A 3oxxC-3fbsA:
undetectable		 3oxxC-3fbsA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 3pwrA-3fbsA:
undetectable		 3pwrA-3fbsA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.80A 3tkgB-3fbsA:
undetectable		 3tkgB-3fbsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 3tkgC-3fbsA:
undetectable		 3tkgC-3fbsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.84A 3tkwB-3fbsA:
undetectable		 3tkwB-3fbsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 3tl9A-3fbsA:
undetectable		 3tl9A-3fbsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.88A 3tl9B-3fbsA:
undetectable		 3tl9B-3fbsA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 11 GLY A  77
VAL A  75
GLU A  76
ASP A  94
ILE A  93
 None
 1.14A 3uawA-3fbsA:
undetectable		 3uawA-3fbsA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.90A 4njvD-3fbsA:
undetectable		 4njvD-3fbsA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		3 / 3 ARG A  36
GLU A  61
TYR A  12
 None
None
FAD  A 298 (-4.7A)
 0.98A 4r29D-3fbsA:
undetectable		 4r29D-3fbsA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.87A 5kqxA-3fbsA:
undetectable		 5kqxA-3fbsA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 10 LEU A 234
LEU A 104
GLU A  92
VAL A  79
ILE A   8
 None
None
None
FAD  A 298 (-4.0A)
None
 1.07A 5v02B-3fbsA:
undetectable
5v02R-3fbsA:
undetectable		 5v02B-3fbsA:
14.63
5v02R-3fbsA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_B_NOVB403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 7 ARG A 103
LEU A 104
ALA A  82
GLN A 254
 None
 1.06A 6b89A-3fbsA:
undetectable		 6b89A-3fbsA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		4 / 8 ILE A 105
ILE A  28
THR A  71
TYR A  69
 None
 0.95A 6cduG-3fbsA:
undetectable
6cduH-3fbsA:
undetectable		 6cduG-3fbsA:
21.01
6cduH-3fbsA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.85A 6dh6A-3fbsA:
undetectable		 6dh6A-3fbsA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.83A 6difB-3fbsA:
undetectable		 6difB-3fbsA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3fbs OXIDOREDUCTASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 284
ALA A  17
ILE A  66
GLY A  22
ILE A   7
 None
 0.83A 6dilB-3fbsA:
undetectable		 6dilB-3fbsA:
13.90