SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 9 ASP A 369
GLY A 368
ASP A 373
PRO A 391
ILE A 375
 CA  A 809 ( 4.9A)
CA  A 809 ( 4.4A)
None
CA  A 812 (-4.7A)
None
 0.99A 1hxwA-3fbyA:
undetectable		 1hxwA-3fbyA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 12 ASP A 369
GLY A 368
ASP A 373
PRO A 391
ILE A 375
 CA  A 809 ( 4.9A)
CA  A 809 ( 4.4A)
None
CA  A 812 (-4.7A)
None
 0.91A 1rl8A-3fbyA:
undetectable		 1rl8A-3fbyA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 PRO A 478
ASP A 475
ASP A 472
 None
CA  A 823 ( 2.7A)
CA  A 821 (-2.7A)
 0.77A 1sqfA-3fbyA:
undetectable		 1sqfA-3fbyA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 PHE A 586
GLN A 616
TRP A 614
GLU A 701
 None
CA  A 828 (-3.0A)
None
None
 1.45A 2aowA-3fbyA:
undetectable		 2aowA-3fbyA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 12 ASP A 378
ASN A 382
GLY A 377
ASP A 363
ASP A 369
 CA  A 812 ( 2.9A)
CA  A 811 ( 4.8A)
CA  A 810 ( 4.1A)
CA  A 810 ( 3.0A)
CA  A 809 ( 4.9A)
 1.49A 2fqyA-3fbyA:
undetectable		 2fqyA-3fbyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 394
ASP A 378
ASP A 397
 None
CA  A 812 ( 2.9A)
CA  A 813 (-3.2A)
 0.78A 2igtB-3fbyA:
undetectable		 2igtB-3fbyA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_C_CTCC1385_0
(TETX2 PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 12 GLN A 604
GLY A 440
SER A 454
PRO A 690
GLY A 693
 None
 1.33A 2y6rC-3fbyA:
undetectable		 2y6rC-3fbyA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 ASP A 369
GLY A 368
ASP A 373
PRO A 391
ILE A 375
 CA  A 809 ( 4.9A)
CA  A 809 ( 4.4A)
None
CA  A 812 (-4.7A)
None
 0.96A 3ekxA-3fbyA:
undetectable		 3ekxA-3fbyA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 5 ARG A 445
ASP A 422
ASP A 431
ASP A 428
 None
CA  A 815 ( 3.0A)
CA  A 816 ( 2.6A)
None
 1.28A 3naiC-3fbyA:
undetectable		 3naiC-3fbyA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 12 ASP A 466
ASP A 469
GLY A 476
ASP A 475
ASP A 462
 None
CA  A 820 (-2.6A)
None
CA  A 823 ( 2.7A)
CA  A 819 ( 2.8A)
 1.01A 3prsA-3fbyA:
undetectable		 3prsA-3fbyA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 ASP A 271
ASP A 290
PRO A 276
ARG A 285
 CA  A 801 ( 2.8A)
CA  A 802 ( 2.3A)
None
None
 1.22A 3s3oA-3fbyA:
undetectable		 3s3oA-3fbyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_C_T1CC401_1
(TETX2 PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 GLN A 604
GLY A 440
SER A 454
PRO A 690
GLY A 693
 None
 1.40A 3v3oC-3fbyA:
undetectable		 3v3oC-3fbyA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 558
ARG A 683
ASP A 273
 SO4  A1001 (-3.8A)
None
CA  A 801 ( 2.9A)
 0.97A 3wipG-3fbyA:
undetectable
3wipH-3fbyA:
undetectable		 3wipG-3fbyA:
17.85
3wipH-3fbyA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_C_T1CC392_1
(TETX2 PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 GLN A 604
GLY A 440
SER A 454
PRO A 690
GLY A 693
 None
 1.40A 4a6nC-3fbyA:
undetectable		 4a6nC-3fbyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_B_MIYB391_1
(TETX2 PROTEIN)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 GLN A 604
GLY A 440
SER A 454
PRO A 690
GLY A 693
 None
 1.33A 4a99B-3fbyA:
undetectable		 4a99B-3fbyA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 ASN A 415
ASP A 408
ASN A 409
 CA  A 814 (-3.2A)
CA  A 814 ( 2.5A)
None
 0.71A 4agaA-3fbyA:
undetectable		 4agaA-3fbyA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 ASN A 489
ASP A 482
ASN A 483
 CA  A 823 (-3.1A)
CA  A 823 ( 2.8A)
None
 0.73A 4agaA-3fbyA:
undetectable		 4agaA-3fbyA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 6 SER A 681
GLU A 559
ASP A 310
ASP A 271
 None
None
None
CA  A 801 ( 2.8A)
 1.38A 4blvA-3fbyA:
undetectable		 4blvA-3fbyA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.11A 4feuF-3fbyA:
undetectable		 4feuF-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.09A 4fevD-3fbyA:
undetectable		 4fevD-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.10A 4fevF-3fbyA:
undetectable		 4fevF-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.08A 4fewD-3fbyA:
undetectable		 4fewD-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.11A 4fewF-3fbyA:
undetectable		 4fewF-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.10A 4fexB-3fbyA:
undetectable		 4fexB-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.08A 4gkhB-3fbyA:
undetectable		 4gkhB-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.10A 4gkhF-3fbyA:
undetectable		 4gkhF-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 7 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.10A 4gkhG-3fbyA:
undetectable		 4gkhG-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 6 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.14A 4gkhJ-3fbyA:
undetectable		 4gkhJ-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.08A 4gkhC-3fbyA:
undetectable
4gkhK-3fbyA:
undetectable		 4gkhC-3fbyA:
20.50
4gkhK-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 358
ASP A 340
CSS A 371
ASP A 349
 None
CA  A 807 ( 2.8A)
None
CA  A 808 ( 2.2A)
 1.20A 4gkiA-3fbyA:
undetectable		 4gkiA-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.10A 4gkiA-3fbyA:
undetectable		 4gkiA-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.11A 4gkiC-3fbyA:
undetectable		 4gkiC-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 466
ASP A 462
ASP A 482
ASN A 474
 None
CA  A 819 ( 2.8A)
CA  A 823 ( 2.8A)
CA  A 820 (-2.9A)
 1.11A 4gkiE-3fbyA:
undetectable
4gkiG-3fbyA:
undetectable		 4gkiE-3fbyA:
20.50
4gkiG-3fbyA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 5 PRO A 633
GLY A 675
ASP A 659
ASP A 670
 None
 0.94A 4n48B-3fbyA:
undetectable		 4n48B-3fbyA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 290
ASP A 271
ASN A 589
 CA  A 802 ( 2.3A)
CA  A 801 ( 2.8A)
None
 0.75A 4q5mA-3fbyA:
undetectable		 4q5mA-3fbyA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 ASP A 595
GLN A 729
ALA A 597
VAL A 588
ASP A 678
 CA  A 829 ( 2.4A)
None
None
None
CA  A 828 (-2.6A)
 1.25A 4uuuA-3fbyA:
undetectable
4uuuB-3fbyA:
undetectable		 4uuuA-3fbyA:
13.41
4uuuB-3fbyA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		5 / 11 ASP A 595
GLN A 729
ALA A 597
VAL A 588
ASP A 678
 CA  A 829 ( 2.4A)
None
None
None
CA  A 828 (-2.6A)
 1.25A 4uuuB-3fbyA:
undetectable		 4uuuB-3fbyA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN
(Homo
sapiens) 		4 / 8 ASP A 594
ASP A 593
ASP A 595
ILE A 547
 CA  A 829 (-3.5A)
CA  A 827 (-2.4A)
CA  A 829 ( 2.4A)
None
 0.97A 4xjeA-3fbyA:
undetectable		 4xjeA-3fbyA:
15.48