SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3fc3 RESTRICTION
ENDONUCLEASE HPY99I
(Helicobacter
pylori) 		3 / 3 VAL A 139
SER A 137
LEU A 145
 None
 0.76A 3n8xA-3fc3A:
undetectable		 3n8xA-3fc3A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3fc3 RESTRICTION
ENDONUCLEASE HPY99I
(Helicobacter
pylori) 		4 / 8 GLU A  52
ASP A  55
ILE A  54
ILE A  67
 None
PG4  A 400 (-4.4A)
PG4  A 400 (-4.2A)
None
 0.88A 4ndnB-3fc3A:
undetectable		 4ndnB-3fc3A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3fc3 RESTRICTION
ENDONUCLEASE HPY99I
(Helicobacter
pylori) 		3 / 3 ALA A 143
ASN A 144
LEU A 145
 None
 0.49A 5i1pD-3fc3A:
undetectable		 5i1pD-3fc3A:
12.17