SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		4 / 6 VAL A 212
ASP A 210
SER A 237
ALA A 195
 None
 0.96A 4nedA-3fc7A:
undetectable		 4nedA-3fc7A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		4 / 8 THR A 241
GLY A 214
GLY A 213
VAL A 212
 None
 0.76A 4qvvK-3fc7A:
undetectable
4qvvL-3fc7A:
undetectable		 4qvvK-3fc7A:
22.48
4qvvL-3fc7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		4 / 8 THR A 241
GLY A 214
GLY A 213
VAL A 212
 None
 0.76A 4qvvY-3fc7A:
undetectable
4qvvZ-3fc7A:
undetectable		 4qvvY-3fc7A:
22.48
4qvvZ-3fc7A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		3 / 3 HIS A 218
ASN A 219
ALA A 195
 None
 0.79A 5n4tB-3fc7A:
undetectable		 5n4tB-3fc7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		4 / 8 GLY A 213
ARG A 192
GLN A 191
ASP A 210
 None
 1.00A 5vlmB-3fc7A:
undetectable		 5vlmB-3fc7A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3fc7 HTR-LIKE PROTEIN
(Haloarcula
marismortui) 		4 / 8 ILE A 222
ARG A 238
GLU A 209
SER A 208
 None
 1.14A 6c06C-3fc7A:
undetectable		 6c06C-3fc7A:
undetectable