SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fch'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		5 / 9 ALA A 206
ILE A 253
VAL A  60
GLY A 201
ILE A 250
 None
 0.92A 1hshB-3fchA:
undetectable		 1hshB-3fchA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		5 / 12 ALA A 206
ILE A 253
VAL A  60
GLY A 201
ILE A 250
 None
 0.93A 2rkgB-3fchA:
undetectable		 2rkgB-3fchA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		5 / 12 ILE A 118
GLY A 124
ALA A 122
ALA A 223
VAL A 224
 None
 0.95A 3jb2A-3fchA:
undetectable		 3jb2A-3fchA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		5 / 12 ILE A 253
ALA A 207
PRO A 199
ALA A 200
VAL A  60
 None
 0.92A 3jb2A-3fchA:
undetectable		 3jb2A-3fchA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		5 / 12 ILE A 253
ALA A 207
PRO A 199
ALA A 200
VAL A  60
 None
 1.00A 3jb3A-3fchA:
2.3		 3jb3A-3fchA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		3 / 3 ARG A 248
ASP A 238
GLN A  68
 None
 0.74A 3lcvB-3fchA:
undetectable		 3lcvB-3fchA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3fch CARBOXYSOME SHELL
PROTEIN CSOS1D
(Prochlorococcus
marinus) 		4 / 8 VAL A 221
ASP A 220
GLY A 183
ALA A 207
 None
 0.75A 4m48A-3fchA:
undetectable		 4m48A-3fchA:
20.15