SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fcn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 3fcn AN ALPHA-HELICAL
PROTEIN OF UNKNOWN
FUNCTION (PFAM01724)
(Rhodospirillum
rubrum) 		3 / 3 ASP A 153
PHE A 150
VAL A  68
 None
 0.50A 1kijB-3fcnA:
undetectable		 1kijB-3fcnA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3fcn AN ALPHA-HELICAL
PROTEIN OF UNKNOWN
FUNCTION (PFAM01724)
(Rhodospirillum
rubrum) 		4 / 4 LEU A 146
VAL A  61
CYH A  65
ALA A 115
 None
 1.17A 1mz9E-3fcnA:
undetectable		 1mz9E-3fcnA:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 3fcn AN ALPHA-HELICAL
PROTEIN OF UNKNOWN
FUNCTION (PFAM01724)
(Rhodospirillum
rubrum) 		5 / 12 GLY A 109
VAL A 116
ILE A  98
ARG A  62
ALA A  57
 None
 0.88A 6c2mD-3fcnA:
undetectable		 6c2mD-3fcnA:
17.47