SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 10 GLY A 163
PHE A 198
MET A 161
LEU A  97
LEU A 128
 None
 1.46A 1a8uB-3fd0A:
2.4		 1a8uB-3fd0A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 ASN A 227
GLY A 231
GLY A 230
ALA A 286
LEU A 315
 LLP  A 226 ( 4.7A)
None
None
None
None
 0.92A 1bx4A-3fd0A:
undetectable		 1bx4A-3fd0A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 6 ASP A 136
GLY A 163
ILE A 164
ILE A 155
 None
None
None
EDO  A 424 (-4.2A)
 0.89A 1n49D-3fd0A:
undetectable		 1n49D-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 9 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.93A 1ohrB-3fd0A:
undetectable		 1ohrB-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 5 PRO A 212
VAL A 215
VAL A 185
ILE A 181
 None
PEG  A 428 (-4.4A)
None
None
 1.04A 1z2bC-3fd0A:
undetectable		 1z2bC-3fd0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 PHE A  71
VAL A  78
LEU A  63
VAL A  66
GLY A 229
 None
None
None
None
LLP  A 226 ( 3.7A)
 1.10A 2cbrA-3fd0A:
undetectable		 2cbrA-3fd0A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		6 / 12 ALA A 217
ASP A 218
ILE A 219
GLY A 163
ALA A 221
ILE A 220
 None
EDO  A 416 ( 4.8A)
None
None
None
None
 1.33A 2rkfB-3fd0A:
undetectable		 2rkfB-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UYQ_A_SAMA1311_0
(HYPOTHETICAL PROTEIN
ML2640)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 7 ALA A 286
GLY A 289
VAL A 396
LEU A 371
 None
None
None
LLP  A 226 ( 4.1A)
 0.76A 2uyqA-3fd0A:
3.9		 2uyqA-3fd0A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 237
GLY A  85
ILE A 225
ALA A 233
THR A  91
 None
LLP  A 226 ( 3.5A)
LLP  A 226 ( 4.3A)
None
None
 1.25A 2vdvE-3fd0A:
undetectable		 2vdvE-3fd0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 11 GLY A 237
GLY A  85
ILE A 225
ALA A 233
THR A  91
 None
LLP  A 226 ( 3.5A)
LLP  A 226 ( 4.3A)
None
None
 1.25A 2vdvF-3fd0A:
undetectable		 2vdvF-3fd0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 8 GLN A  81
ASP A  57
TYR A  67
SER A 265
 None
 1.27A 2xz5C-3fd0A:
undetectable
2xz5D-3fd0A:
undetectable		 2xz5C-3fd0A:
21.19
2xz5D-3fd0A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 ALA A 286
GLY A 230
GLY A 390
LEU A 224
ALA A 279
 None
 0.87A 3douA-3fd0A:
3.2		 3douA-3fd0A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		3 / 3 ASN A  48
HIS A  46
VAL A  42
 None
 0.84A 3elzB-3fd0A:
undetectable		 3elzB-3fd0A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		3 / 3 SER A  84
GLY A  85
THR A  86
 LLP  A 226 ( 3.3A)
LLP  A 226 ( 3.5A)
LLP  A 226 ( 3.6A)
 0.08A 3k9wA-3fd0A:
undetectable		 3k9wA-3fd0A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 231
GLY A 229
THR A 392
LEU A 391
SER A 223
 None
LLP  A 226 ( 3.7A)
None
EDO  A 418 (-3.9A)
LLP  A 226 ( 3.7A)
 1.24A 3mteA-3fd0A:
undetectable		 3mteA-3fd0A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 9 GLY A 216
ALA A 217
ASP A 218
ILE A 219
MET A 161
 EDO  A 416 (-3.4A)
None
EDO  A 416 ( 4.8A)
None
None
 0.96A 3ogpB-3fd0A:
undetectable		 3ogpB-3fd0A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 216
ALA A 217
ASP A 218
ILE A 219
MET A 161
 EDO  A 416 (-3.4A)
None
EDO  A 416 ( 4.8A)
None
None
 0.77A 3ogqB-3fd0A:
undetectable		 3ogqB-3fd0A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 8 SER A 167
SER A 370
ASP A 200
THR A  86
 LLP  A 226 ( 4.1A)
LLP  A 226 ( 4.2A)
LLP  A 226 ( 2.8A)
LLP  A 226 ( 3.6A)
 0.81A 3pwwA-3fd0A:
undetectable		 3pwwA-3fd0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 4 ASP A 314
GLY A 169
TYR A 203
GLN A 388
 None
EDO  A 411 (-3.8A)
LLP  A 226 ( 3.5A)
EDO  A 411 (-3.5A)
 1.17A 3w9tC-3fd0A:
0.0		 3w9tC-3fd0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 5 ASP A 314
GLY A 169
TYR A 203
GLN A 388
 None
EDO  A 411 (-3.8A)
LLP  A 226 ( 3.5A)
EDO  A 411 (-3.5A)
 1.06A 3w9tD-3fd0A:
undetectable		 3w9tD-3fd0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 5 ASP A 314
GLY A 169
TYR A 203
GLN A 388
 None
EDO  A 411 (-3.8A)
LLP  A 226 ( 3.5A)
EDO  A 411 (-3.5A)
 1.12A 3w9tE-3fd0A:
undetectable		 3w9tE-3fd0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 5 ASP A 314
GLY A 169
TYR A 203
GLN A 388
 None
EDO  A 411 (-3.8A)
LLP  A 226 ( 3.5A)
EDO  A 411 (-3.5A)
 1.08A 3w9tG-3fd0A:
undetectable		 3w9tG-3fd0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.91A 4dqfA-3fd0A:
undetectable		 4dqfA-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		3 / 3 ASP A 200
LEU A  93
VAL A 246
 LLP  A 226 ( 2.8A)
None
None
 0.68A 4jecB-3fd0A:
undetectable		 4jecB-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 8 SER A 407
LEU A 385
VAL A 387
ILE A 334
 None
 0.86A 4oj4A-3fd0A:
undetectable		 4oj4A-3fd0A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_A_ACTA1229_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		4 / 4 VAL A  70
GLU A 211
THR A 213
GLU A 214
 None
None
None
PEG  A 427 ( 4.6A)
 1.41A 5g5hA-3fd0A:
0.0		 5g5hA-3fd0A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 VAL A 387
ALA A 331
MET A 327
GLY A 348
TYR A 354
 None
 1.10A 5igiA-3fd0A:
undetectable		 5igiA-3fd0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 10 LEU A 114
GLY A  95
ILE A  96
VAL A 118
ILE A 117
 None
 0.89A 5kr1A-3fd0A:
undetectable		 5kr1A-3fd0A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 144
ILE A 106
VAL A 151
ASP A 147
ILE A 146
 None
None
None
None
EDO  A 413 (-4.3A)
 0.80A 6emuA-3fd0A:
undetectable		 6emuA-3fd0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 144
ILE A 106
VAL A 151
ASP A 147
ILE A 146
 None
None
None
None
EDO  A 413 (-4.3A)
 0.83A 6emuB-3fd0A:
undetectable		 6emuB-3fd0A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE
(Listeria
innocua) 		5 / 12 GLY A 144
ILE A 106
VAL A 151
ASP A 147
ILE A 146
 None
None
None
None
EDO  A 413 (-4.3A)
 0.84A 6emuC-3fd0A:
undetectable		 6emuC-3fd0A:
20.05