SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 4 VAL A 235
TRP A 240
TRP A 131
 None
 1.09A 1gmkA-3fd9A:
undetectable
1gmkB-3fd9A:
undetectable		 1gmkA-3fd9A:
4.74
1gmkB-3fd9A:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 240
PHE A 229
TRP A 210
 None
 1.47A 1r15F-3fd9A:
undetectable		 1r15F-3fd9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 240
PHE A 229
TRP A 210
 None
 1.49A 1r15G-3fd9A:
undetectable		 1r15G-3fd9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 240
PHE A 229
TRP A 210
 None
 1.48A 1r15H-3fd9A:
undetectable		 1r15H-3fd9A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 236
LEU A 239
LEU A 124
MET A 119
LEU A 226
 None
 1.11A 1sqnB-3fd9A:
undetectable		 1sqnB-3fd9A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 220
LEU A 221
ILE A 120
PHE A 229
LEU A 125
 None
 1.20A 2q6hA-3fd9A:
undetectable		 2q6hA-3fd9A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 120
PHE A 229
TRP A 240
GLY A 224
 None
 0.84A 2qx4A-3fd9A:
undetectable
2qx4B-3fd9A:
undetectable		 2qx4A-3fd9A:
21.55
2qx4B-3fd9A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 132
LEU A 135
ASP A 136
 None
 0.41A 3ko0A-3fd9A:
undetectable		 3ko0A-3fd9A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 132
LEU A 135
ASP A 136
 None
 0.35A 3ko0T-3fd9A:
undetectable		 3ko0T-3fd9A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 260
VAL A 111
LEU A 113
ALA A 253
 None
 0.91A 3uniB-3fd9A:
2.3		 3uniB-3fd9A:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)		 3fd9 UNCHARACTERIZED
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 226
VAL A 256
VAL A 123
TRP A 274
PRO A 242
 None
 1.29A 4kfbA-3fd9A:
undetectable		 4kfbA-3fd9A:
17.50