SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		4 / 4 ALA A 173
VAL A 168
ALA A 163
HIS A 160
 None
 1.23A 1q23F-3fdjA:
undetectable		 1q23F-3fdjA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		4 / 4 ALA A 173
VAL A 168
ALA A 163
HIS A 160
 None
 1.17A 1q23K-3fdjA:
undetectable		 1q23K-3fdjA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		4 / 6 ARG A 108
LEU A   3
ALA A   5
LEU A 126
 None
 0.96A 1ukbA-3fdjA:
undetectable		 1ukbA-3fdjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		4 / 7 MET A   1
ILE A 130
ILE A 139
PHE A 136
 None
 0.84A 1upfB-3fdjA:
undetectable		 1upfB-3fdjA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_A_T98A201_1
(PROGESTERONE
RECEPTOR)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		5 / 10 LEU A 223
LEU A 205
LEU A 213
TYR A 218
THR A 247
 None
 1.43A 1zucA-3fdjA:
undetectable		 1zucA-3fdjA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		3 / 3 LYS A  12
ASP A  40
ASP A  46
 None
 0.84A 2br4A-3fdjA:
2.3		 2br4A-3fdjA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		3 / 3 THR A  28
LYS A  12
GLU A  31
 None
 1.00A 3ijdB-3fdjA:
undetectable		 3ijdB-3fdjA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		5 / 12 GLY A 256
ALA A 255
VAL A 228
ASN A 161
ILE A  26
 None
 1.06A 4pd5A-3fdjA:
undetectable		 4pd5A-3fdjA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		5 / 12 GLY A 256
ALA A 255
VAL A 228
LEU A  45
ILE A  26
 None
 1.19A 4pd5A-3fdjA:
undetectable		 4pd5A-3fdjA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		5 / 12 GLY A 256
ALA A 255
VAL A 228
LEU A  45
ILE A  26
 None
 1.16A 4pd9A-3fdjA:
undetectable		 4pd9A-3fdjA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		5 / 12 LEU A 156
SER A 158
GLU A  49
GLY A 266
GLY A 267
 None
 1.08A 4yvgA-3fdjA:
undetectable		 4yvgA-3fdjA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3fdj DEGV FAMILY PROTEIN
([Eubacterium]
eligens) 		4 / 5 GLY A 116
THR A 115
GLY A 133
LEU A   3
 None
P6G  A 276 ( 3.7A)
None
None
 0.80A 5jlcA-3fdjA:
undetectable		 5jlcA-3fdjA:
20.31