SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		4 / 7 HIS A  47
THR A  25
ASN A  19
GLN A  16
 None
 1.03A 1qzrB-3fdqA:
undetectable		 1qzrB-3fdqA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		5 / 12 LEU A 101
ALA A  82
ILE A  45
ILE A  86
ALA A  87
 None
 1.06A 2bxcA-3fdqA:
undetectable		 2bxcA-3fdqA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		3 / 3 LYS A 111
TYR A  65
PRO A 110
 None
 1.35A 2j9cC-3fdqA:
undetectable		 2j9cC-3fdqA:
28.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		4 / 6 ASP A  38
ILE A  86
GLN A  85
GLU A  44
 None
 1.41A 2ya7C-3fdqA:
undetectable		 2ya7C-3fdqA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		4 / 5 LYS A 135
VAL A  56
ILE A  70
ARG A 107
 None
 1.33A 3pyyB-3fdqA:
undetectable		 3pyyB-3fdqA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 3fdq MOTILITY GENE
REPRESSOR MOGR
(Listeria
monocytogenes) 		4 / 6 CYH A  83
LEU A  79
HIS A  47
LEU A  49
 None
 1.21A 5hpuC-3fdqA:
undetectable
5hpuD-3fdqA:
undetectable		 5hpuC-3fdqA:
13.86
5hpuD-3fdqA:
11.11