SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fdw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 3fdw SYNAPTOTAGMIN-LIKE
PROTEIN 4
(Homo
sapiens) 		4 / 6 THR A 399
LEU A 401
GLY A 409
TYR A 430
 None
 1.18A 1gtiC-3fdwA:
undetectable		 1gtiC-3fdwA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3fdw SYNAPTOTAGMIN-LIKE
PROTEIN 4
(Homo
sapiens) 		4 / 8 THR A 419
THR A 413
VAL A 446
VAL A 397
 None
 0.83A 1t86A-3fdwA:
undetectable		 1t86A-3fdwA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fdw SYNAPTOTAGMIN-LIKE
PROTEIN 4
(Homo
sapiens) 		5 / 11 GLU A 367
LEU A 373
TYR A 430
LEU A 364
LEU A 442
 None
 0.95A 4wg0I-3fdwA:
undetectable
4wg0J-3fdwA:
undetectable
4wg0K-3fdwA:
undetectable		 4wg0I-3fdwA:
9.38
4wg0J-3fdwA:
9.38
4wg0K-3fdwA:
9.38