SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fe4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 7 HIS A 111
HIS A 113
HIS A 138
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.70A 1am6A-3fe4A:
31.3		 1am6A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 7 HIS A 113
HIS A 138
HIS A 111
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
 0.97A 1am6A-3fe4A:
31.3		 1am6A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 7 LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.44A 1am6A-3fe4A:
31.3		 1am6A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 8 HIS A 111
HIS A 113
HIS A 138
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.64A 1azmA-3fe4A:
30.5		 1azmA-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 PHE A 165
HIS A 138
HIS A 113
THR A 220
 None
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
 1.03A 1azmA-3fe4A:
30.5		 1azmA-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 8 HIS A 111
HIS A 113
HIS A 138
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.63A 1bzmA-3fe4A:
30.3		 1bzmA-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 HIS A  85
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 1cilA-3fe4A:
31.5		 1cilA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.45A 1cilA-3fe4A:
31.5		 1cilA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 HIS A 111
HIS A 113
HIS A 138
VAL A 140
TYR A 149
LEU A 159
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.58A 1dmyA-3fe4A:
29.9		 1dmyA-3fe4A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 113
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
 1.22A 1dmyA-3fe4A:
29.9		 1dmyA-3fe4A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 TYR A 149
LEU A 159
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.75A 1dmyA-3fe4A:
29.9		 1dmyA-3fe4A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
TYR A 149
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.56A 1dmyB-3fe4A:
29.9		 1dmyB-3fe4A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 TYR A 149
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.78A 1dmyB-3fe4A:
29.9		 1dmyB-3fe4A:
31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.74A 1jd0A-3fe4A:
33.0		 1jd0A-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 9 HIS A 111
HIS A 113
VAL A 140
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.49A 1jd0A-3fe4A:
33.0		 1jd0A-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.43A 1jd0B-3fe4A:
32.8		 1jd0B-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 1jd0B-3fe4A:
32.8		 1jd0B-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.67A 1jd0B-3fe4A:
32.8		 1jd0B-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.45A 1jd0B-3fe4A:
32.8		 1jd0B-3fe4A:
38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 0.68A 1oq5A-3fe4A:
31.1		 1oq5A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 VAL A 140
LEU A 219
THR A 220
PRO A 223
TRP A 230
 None
 0.58A 1oq5A-3fe4A:
31.1		 1oq5A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.79A 1rj6A-3fe4A:
33.8		 1rj6A-3fe4A:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 1rj6A-3fe4A:
33.8		 1rj6A-3fe4A:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.78A 1rj6B-3fe4A:
33.9		 1rj6B-3fe4A:
38.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 1rj6B-3fe4A:
33.9		 1rj6B-3fe4A:
38.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.85A 1v7zA-3fe4A:
undetectable		 1v7zA-3fe4A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.85A 1v7zB-3fe4A:
undetectable		 1v7zB-3fe4A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.88A 1v7zC-3fe4A:
undetectable		 1v7zC-3fe4A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.83A 1v7zD-3fe4A:
undetectable		 1v7zD-3fe4A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.84A 1v7zE-3fe4A:
undetectable		 1v7zE-3fe4A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.87A 1v7zF-3fe4A:
undetectable		 1v7zF-3fe4A:
24.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 GLN A 109
HIS A 111
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.55A 1ydaA-3fe4A:
31.1		 1ydaA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.58A 1ydbA-3fe4A:
31.3		 1ydbA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 1ydbA-3fe4A:
31.3		 1ydbA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.61A 1yddA-3fe4A:
31.3		 1yddA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 140
VAL A 161
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.22A 1yddA-3fe4A:
31.3		 1yddA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.59A 1z9yA-3fe4A:
31.0		 1z9yA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.47A 1z9yA-3fe4A:
31.0		 1z9yA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.63A 1zgfA-3fe4A:
31.1		 1zgfA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.46A 1zgfA-3fe4A:
31.1		 1zgfA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.44A 1zsbA-3fe4A:
31.5		 1zsbA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 1zsbA-3fe4A:
31.5		 1zsbA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.67A 1zsbA-3fe4A:
31.5		 1zsbA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
None
 0.65A 2aw1A-3fe4A:
30.8		 2aw1A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 1.38A 2aw1A-3fe4A:
30.8		 2aw1A-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 159
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.47A 2aw1A-3fe4A:
30.8		 2aw1A-3fe4A:
34.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 THR A 266
PRO A 268
PRO A  49
 None
 0.84A 2d55C-3fe4A:
undetectable		 2d55C-3fe4A:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 247
ASN A 249
GLY A 116
LEU A 184
LEU A 251
 None
 1.05A 2egvB-3fe4A:
undetectable		 2egvB-3fe4A:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.66A 2gehA-3fe4A:
31.1		 2gehA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.87A 2gehA-3fe4A:
31.1		 2gehA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 9 GLN A 109
HIS A 113
HIS A 138
VAL A 140
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.77A 2h4nA-3fe4A:
31.6		 2h4nA-3fe4A:
33.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.85A 2it4A-3fe4A:
30.3		 2it4A-3fe4A:
34.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.67A 2pouA-3fe4A:
31.0		 2pouA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.48A 2pouA-3fe4A:
31.0		 2pouA-3fe4A:
34.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 ASP A 253
THR A 221
PRO A 222
 None
 0.63A 2pynB-3fe4A:
undetectable		 2pynB-3fe4A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 ASP A 253
THR A 221
PRO A 222
 None
 0.67A 2qakB-3fe4A:
undetectable		 2qakB-3fe4A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.90A 3a6jA-3fe4A:
undetectable		 3a6jA-3fe4A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 7 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.92A 3a6jB-3fe4A:
undetectable		 3a6jB-3fe4A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.89A 3a6jC-3fe4A:
undetectable		 3a6jC-3fe4A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.89A 3a6jE-3fe4A:
undetectable		 3a6jE-3fe4A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 8 HIS A 138
TYR A 263
HIS A 113
GLU A 136
 MG  A 901 (-3.2A)
None
MG  A 901 (-3.4A)
None
 0.90A 3a6jF-3fe4A:
undetectable		 3a6jF-3fe4A:
23.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 161
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.62A 3bl1A-3fe4A:
30.9		 3bl1A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.71A 3bl1A-3fe4A:
30.9		 3bl1A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3cajA-3fe4A:
31.0		 3cajA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 10 HIS A 138
VAL A 140
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
None
 0.72A 3cajA-3fe4A:
31.0		 3cajA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.49A 3cajA-3fe4A:
31.0		 3cajA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.68A 3czvA-3fe4A:
31.0
3czvB-3fe4A:
30.7		 3czvA-3fe4A:
33.57
3czvB-3fe4A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.67A 3czvA-3fe4A:
31.0
3czvB-3fe4A:
30.7		 3czvA-3fe4A:
33.57
3czvB-3fe4A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.67A 3czvB-3fe4A:
30.7		 3czvB-3fe4A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.68A 3czvB-3fe4A:
30.7		 3czvB-3fe4A:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.64A 3dazA-3fe4A:
31.6		 3dazA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 3dazA-3fe4A:
31.6		 3dazA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 113
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
 1.28A 3dazA-3fe4A:
31.6		 3dazA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.48A 3dc3A-3fe4A:
31.7		 3dc3A-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 3dc3A-3fe4A:
31.7		 3dc3A-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.65A 3dc3A-3fe4A:
31.7		 3dc3A-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.48A 3dc3A-3fe4A:
31.7		 3dc3A-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3dcsA-3fe4A:
31.6		 3dcsA-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.62A 3dcwA-3fe4A:
31.6		 3dcwA-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 113
HIS A 138
HIS A 111
THR A 220
PRO A 222
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
None
 1.20A 3dcwA-3fe4A:
31.6		 3dcwA-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.73A 3dcwA-3fe4A:
31.6		 3dcwA-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.49A 3dcwA-3fe4A:
31.6		 3dcwA-3fe4A:
35.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.63A 3dd0A-3fe4A:
31.6		 3dd0A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 3dd0A-3fe4A:
31.6		 3dd0A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 113
HIS A 138
HIS A 111
THR A 220
PRO A 222
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
None
 1.19A 3dd0A-3fe4A:
31.6		 3dd0A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.73A 3dd0A-3fe4A:
31.6		 3dd0A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.47A 3dd0A-3fe4A:
31.6		 3dd0A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.76A 3f4xA-3fe4A:
30.5		 3f4xA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
None
None
 0.82A 3f4xA-3fe4A:
30.5		 3f4xA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.55A 3f4xA-3fe4A:
30.5		 3f4xA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 ASN A  83
HIS A  85
GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.73A 3fw3A-3fe4A:
30.6		 3fw3A-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.64A 3fw3B-3fe4A:
30.3		 3fw3B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 0.61A 3hkuA-3fe4A:
31.3		 3hkuA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.46A 3hkuA-3fe4A:
31.3		 3hkuA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 GLU A 125
HIS A 138
THR A 220
 MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
 0.63A 3hkuA-3fe4A:
31.3		 3hkuA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.62A 3hs4A-3fe4A:
31.3		 3hs4A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.46A 3hs4A-3fe4A:
31.3		 3hs4A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.39A 3iaiA-3fe4A:
33.8		 3iaiA-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3iaiA-3fe4A:
33.8		 3iaiA-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.38A 3iaiB-3fe4A:
34.1		 3iaiB-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3iaiB-3fe4A:
34.1		 3iaiB-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.39A 3iaiC-3fe4A:
34.0		 3iaiC-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3iaiC-3fe4A:
34.0		 3iaiC-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.38A 3iaiD-3fe4A:
34.1		 3iaiD-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.68A 3iaiD-3fe4A:
34.1		 3iaiD-3fe4A:
39.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 GLN A 109
HIS A 111
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.77A 3kwaA-3fe4A:
30.6		 3kwaA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.77A 3kwaA-3fe4A:
30.6		 3kwaA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.58A 3kwaA-3fe4A:
30.6		 3kwaA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 0.82A 3lxeA-3fe4A:
30.5		 3lxeA-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 0.82A 3lxeB-3fe4A:
30.4		 3lxeB-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
HIS A 113
THR A 220
THR A 221
PRO A 223
 MG  A 901 ( 4.4A)
MG  A 901 (-3.4A)
None
None
None
 1.23A 3mdzA-3fe4A:
31.0		 3mdzA-3fe4A:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
None
 0.64A 3mdzA-3fe4A:
31.0		 3mdzA-3fe4A:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 3mdzA-3fe4A:
31.0		 3mdzA-3fe4A:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.72A 3mdzA-3fe4A:
31.0		 3mdzA-3fe4A:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 113
HIS A 138
HIS A 111
THR A 220
PRO A 222
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
None
 1.15A 3mdzA-3fe4A:
31.0		 3mdzA-3fe4A:
35.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.70A 3ml5A-3fe4A:
31.1		 3ml5A-3fe4A:
36.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.59A 3v2jA-3fe4A:
31.7		 3v2jA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.50A 3v2jA-3fe4A:
31.7		 3v2jA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.66A 3v2mA-3fe4A:
31.3		 3v2mA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 GLN A 109
HIS A 111
HIS A 113
HIS A 138
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.73A 3w6hA-3fe4A:
30.3		 3w6hA-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
 0.72A 3w6hB-3fe4A:
30.3		 3w6hB-3fe4A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.74A 3zncA-3fe4A:
30.5		 3zncA-3fe4A:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.20A 3zncA-3fe4A:
30.5		 3zncA-3fe4A:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 138
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
None
None
 1.47A 3zncA-3fe4A:
30.5		 3zncA-3fe4A:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 138
HIS A 126
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.2A)
None
None
None
None
 1.48A 3zncA-3fe4A:
30.5		 3zncA-3fe4A:
34.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 7 LEU A 219
GLU A 136
HIS A 138
HIS A 111
 None
None
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
 1.33A 4aq7A-3fe4A:
undetectable		 4aq7A-3fe4A:
14.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.63A 4coqA-3fe4A:
26.5		 4coqA-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 10 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.47A 4coqA-3fe4A:
26.5		 4coqA-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.63A 4coqB-3fe4A:
26.5		 4coqB-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 9 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.49A 4coqB-3fe4A:
26.5		 4coqB-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 9 HIS A 138
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
None
None
 1.43A 4coqB-3fe4A:
26.5		 4coqB-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 GLN A 109
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
VAL A 228
TRP A 230
 None
 0.58A 4e3hA-3fe4A:
31.1		 4e3hA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 10 LEU A 159
LEU A 219
THR A 220
THR A 221
VAL A 228
TRP A 230
 None
 0.55A 4e3hA-3fe4A:
31.1		 4e3hA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.48A 4g0cA-3fe4A:
31.6		 4g0cA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.62A 4g0cA-3fe4A:
31.6		 4g0cA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.66A 4g0cA-3fe4A:
31.6		 4g0cA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 111
HIS A 113
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 1.25A 4g0cA-3fe4A:
31.6		 4g0cA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 113
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
 1.27A 4g0cA-3fe4A:
31.6		 4g0cA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.43A 4g7aA-3fe4A:
26.5		 4g7aA-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.62A 4g7aA-3fe4A:
26.5		 4g7aA-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.67A 4g7aA-3fe4A:
26.5		 4g7aA-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.46A 4g7aA-3fe4A:
26.5		 4g7aA-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.40A 4g7aB-3fe4A:
26.4		 4g7aB-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.65A 4g7aB-3fe4A:
26.4		 4g7aB-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.68A 4g7aB-3fe4A:
26.4		 4g7aB-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.48A 4g7aB-3fe4A:
26.4		 4g7aB-3fe4A:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 4k0sA-3fe4A:
31.2		 4k0sA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 4k0zA-3fe4A:
31.1		 4k0zA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 113
HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 1.48A 4k0zA-3fe4A:
31.1		 4k0zA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.77A 4k0zA-3fe4A:
31.1		 4k0zA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.52A 4k0zA-3fe4A:
31.1		 4k0zA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.64A 4k13A-3fe4A:
31.3		 4k13A-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 1.41A 4k13A-3fe4A:
31.3		 4k13A-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 159
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.54A 4k13A-3fe4A:
31.3		 4k13A-3fe4A:
34.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A  32
PRO A  49
GLU A 136
TRP A 230
HIS A 111
 None
None
None
None
MG  A 901 (-3.4A)
 1.49A 4k88A-3fe4A:
undetectable		 4k88A-3fe4A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLY A 158
ALA A 160
LEU A 159
HIS A 141
GLN A 108
 None
 0.95A 4l8fB-3fe4A:
undetectable		 4l8fB-3fe4A:
22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.38A 4lu3A-3fe4A:
33.5		 4lu3A-3fe4A:
38.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.64A 4lu3A-3fe4A:
33.5		 4lu3A-3fe4A:
38.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.71A 4lu3A-3fe4A:
33.5		 4lu3A-3fe4A:
38.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.70A 4m2rA-3fe4A:
31.5		 4m2rA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.46A 4m2rA-3fe4A:
31.5		 4m2rA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
None
None
 0.75A 4m2rA-3fe4A:
31.5		 4m2rA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.53A 4m2rA-3fe4A:
31.5		 4m2rA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 4 HIS A  85
GLU A 125
HIS A 138
LEU A 159
 None
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
 0.56A 4m2rA-3fe4A:
31.5		 4m2rA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 HIS A  85
GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.75A 4m2uA-3fe4A:
31.7		 4m2uA-3fe4A:
34.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.62A 4m2vA-3fe4A:
31.7		 4m2vA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.48A 4m2vA-3fe4A:
31.7		 4m2vA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.58A 4m2wA-3fe4A:
31.7		 4m2wA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 1.37A 4m2wA-3fe4A:
31.7		 4m2wA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 159
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.54A 4m2wA-3fe4A:
31.7		 4m2wA-3fe4A:
34.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 8 GLN A 109
HIS A 111
HIS A 113
HIS A 138
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
 0.69A 4n16A-3fe4A:
31.4		 4n16A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 8 ILE A 259
HIS A 113
HIS A 138
HIS A 111
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
MG  A 901 (-3.4A)
None
 1.33A 4n16A-3fe4A:
31.4		 4n16A-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
 0.71A 4pxxA-3fe4A:
31.4		 4pxxA-3fe4A:
35.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 113
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
 0.72A 4twlA-3fe4A:
24.7		 4twlA-3fe4A:
29.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 113
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
 0.73A 4twlB-3fe4A:
24.9		 4twlB-3fe4A:
29.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.47A 4uovA-3fe4A:
26.7		 4uovA-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.67A 4uovA-3fe4A:
26.7		 4uovA-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.45A 4uovB-3fe4A:
26.7		 4uovB-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.62A 4uovB-3fe4A:
26.7		 4uovB-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.48A 4uovC-3fe4A:
26.7		 4uovC-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 4uovC-3fe4A:
26.7		 4uovC-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.47A 4uovD-3fe4A:
26.7		 4uovD-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.65A 4uovD-3fe4A:
26.7		 4uovD-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.48A 4uovE-3fe4A:
26.7		 4uovE-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.67A 4uovE-3fe4A:
26.7		 4uovE-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.46A 4uovF-3fe4A:
26.8		 4uovF-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 4uovF-3fe4A:
26.8		 4uovF-3fe4A:
30.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
None
MG  A 901 (-3.2A)
None
None
None
 1.44A 4x5sA-3fe4A:
26.3		 4x5sA-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 4x5sA-3fe4A:
26.3		 4x5sA-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.62A 4x5sA-3fe4A:
26.3		 4x5sA-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
None
MG  A 901 (-3.2A)
None
None
None
 1.44A 4x5sB-3fe4A:
26.3		 4x5sB-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.65A 4x5sB-3fe4A:
26.3		 4x5sB-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.61A 4x5sB-3fe4A:
26.3		 4x5sB-3fe4A:
31.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.40A 4xiwA-3fe4A:
24.5
4xiwH-3fe4A:
24.2		 4xiwA-3fe4A:
32.30
4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.72A 4xiwA-3fe4A:
24.5
4xiwH-3fe4A:
24.2		 4xiwA-3fe4A:
32.30
4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.69A 4xiwA-3fe4A:
24.5
4xiwH-3fe4A:
24.2		 4xiwA-3fe4A:
32.30
4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.43A 4xiwA-3fe4A:
24.5
4xiwH-3fe4A:
24.2		 4xiwA-3fe4A:
32.30
4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.40A 4xiwB-3fe4A:
24.4
4xiwE-3fe4A:
24.4		 4xiwB-3fe4A:
32.30
4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.72A 4xiwB-3fe4A:
24.4
4xiwE-3fe4A:
24.4		 4xiwB-3fe4A:
32.30
4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.68A 4xiwB-3fe4A:
24.4
4xiwE-3fe4A:
24.4		 4xiwB-3fe4A:
32.30
4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.29A 4xiwC-3fe4A:
24.5		 4xiwC-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 4xiwC-3fe4A:
24.5		 4xiwC-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.68A 4xiwC-3fe4A:
24.5		 4xiwC-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.48A 4xiwC-3fe4A:
24.5		 4xiwC-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.33A 4xiwD-3fe4A:
24.5		 4xiwD-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.69A 4xiwD-3fe4A:
24.5		 4xiwD-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.70A 4xiwD-3fe4A:
24.5		 4xiwD-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.47A 4xiwD-3fe4A:
24.5		 4xiwD-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.36A 4xiwE-3fe4A:
24.4		 4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.70A 4xiwE-3fe4A:
24.4		 4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.69A 4xiwE-3fe4A:
24.4		 4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.49A 4xiwE-3fe4A:
24.4		 4xiwE-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.45A 4xiwF-3fe4A:
24.3		 4xiwF-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.61A 4xiwF-3fe4A:
24.3		 4xiwF-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.43A 4xiwF-3fe4A:
24.3		 4xiwF-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		11 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.69A 4xiwG-3fe4A:
24.2		 4xiwG-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
VAL A 140
LEU A 159
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 1.32A 4xiwG-3fe4A:
24.2		 4xiwG-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
None
 1.36A 4xiwH-3fe4A:
24.2		 4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.75A 4xiwH-3fe4A:
24.2		 4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.78A 4xiwH-3fe4A:
24.2		 4xiwH-3fe4A:
32.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 1.49A 4xiwH-3fe4A:
24.2		 4xiwH-3fe4A:
32.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.75A 4ygfA-3fe4A:
22.9		 4ygfA-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.66A 4ygfB-3fe4A:
22.5		 4ygfB-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 4ygfC-3fe4A:
18.7		 4ygfC-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 11 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.68A 4ygfD-3fe4A:
9.4		 4ygfD-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 11 HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
 MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
 1.16A 4ygfD-3fe4A:
9.4		 4ygfD-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 4ygfE-3fe4A:
22.9		 4ygfE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.72A 4ygfF-3fe4A:
23.0		 4ygfF-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.62A 4ygfG-3fe4A:
22.9		 4ygfG-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.73A 4ygfH-3fe4A:
23.0		 4ygfH-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.63A 4ygfH-3fe4A:
23.0		 4ygfH-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.84A 4yhaA-3fe4A:
22.5		 4yhaA-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.65A 4yhaA-3fe4A:
22.5		 4yhaA-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.77A 4yhaB-3fe4A:
22.0		 4yhaB-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.77A 4yhaC-3fe4A:
22.6		 4yhaC-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 11 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.64A 4yhaC-3fe4A:
22.6		 4yhaC-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.76A 4yhaD-3fe4A:
22.1		 4yhaD-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.79A 4yhaE-3fe4A:
22.7		 4yhaE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.66A 4yhaE-3fe4A:
22.7		 4yhaE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 HIS A 113
HIS A 138
LEU A 219
THR A 220
PRO A 222
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 1.47A 4yhaE-3fe4A:
22.7		 4yhaE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.89A 4yhaE-3fe4A:
22.7		 4yhaE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.84A 4yhaE-3fe4A:
22.7		 4yhaE-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
 0.64A 4yhaF-3fe4A:
20.7		 4yhaF-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.80A 4yhaG-3fe4A:
22.6		 4yhaG-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.69A 4yhaG-3fe4A:
22.6		 4yhaG-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.79A 4yhaH-3fe4A:
22.6		 4yhaH-3fe4A:
28.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 111
HIS A 113
GLU A 125
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
None
None
None
None
None
 0.67A 5c8iA-3fe4A:
31.7		 5c8iA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 GLN A 109
HIS A 113
GLU A 125
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
None
None
None
None
None
None
 0.81A 5c8iA-3fe4A:
31.7		 5c8iA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 GLU A 125
VAL A 140
LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
None
None
 0.73A 5c8iA-3fe4A:
31.7		 5c8iA-3fe4A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 5jn8A-3fe4A:
30.0		 5jn8A-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.48A 5jn8B-3fe4A:
30.6		 5jn8B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 5jn8B-3fe4A:
30.6		 5jn8B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.75A 5jn8C-3fe4A:
29.9		 5jn8C-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 10 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
TRP A 230
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.43A 5jn8D-3fe4A:
29.8		 5jn8D-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.73A 5jn8D-3fe4A:
29.8		 5jn8D-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 GLU A 125
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
None
None
None
None
 0.58A 5jn8D-3fe4A:
29.8		 5jn8D-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.68A 5jn9A-3fe4A:
29.9		 5jn9A-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.68A 5jn9B-3fe4A:
30.6		 5jn9B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 HIS A 138
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
 0.70A 5jn9B-3fe4A:
30.6		 5jn9B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.68A 5jn9C-3fe4A:
29.8		 5jn9C-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.63A 5jn9D-3fe4A:
29.7		 5jn9D-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
THR A 220
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
 0.63A 5jnaA-3fe4A:
30.1		 5jnaA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 12 ASN A  83
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.75A 5jnaA-3fe4A:
30.1		 5jnaA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 12 GLN A 109
HIS A 111
GLU A 136
HIS A 138
VAL A 140
VAL A 161
 None
MG  A 901 (-3.4A)
None
MG  A 901 (-3.2A)
None
None
 1.49A 5jnaA-3fe4A:
30.1		 5jnaA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 GLU A 125
HIS A 138
LEU A 219
THR A 220
THR A 221
 MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
 0.74A 5jnaA-3fe4A:
30.1		 5jnaA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.75A 5jnaB-3fe4A:
30.7		 5jnaB-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 HIS A 138
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
 0.66A 5jnaB-3fe4A:
30.7		 5jnaB-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 ASN A  83
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.61A 5jnaC-3fe4A:
29.9		 5jnaC-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 11 ASN A  83
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.74A 5jnaC-3fe4A:
29.9		 5jnaC-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.69A 5jnaD-3fe4A:
29.8		 5jnaD-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		10 / 11 GLN A 109
HIS A 111
HIS A 113
GLU A 125
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 5jncA-3fe4A:
30.1		 5jncA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		6 / 11 GLU A 125
HIS A 138
LEU A 219
THR A 220
THR A 221
TRP A 230
 MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.70A 5jncA-3fe4A:
30.1		 5jncA-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.64A 5jncB-3fe4A:
30.7		 5jncB-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 10 VAL A 161
LEU A 219
THR A 220
THR A 221
TRP A 230
 None
 0.62A 5jncB-3fe4A:
30.7		 5jncB-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.72A 5jncC-3fe4A:
29.8		 5jncC-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.68A 5jncD-3fe4A:
29.8		 5jncD-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.73A 5ku6A-3fe4A:
30.0		 5ku6A-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		9 / 10 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.69A 5ku6B-3fe4A:
30.6		 5ku6B-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.76A 5ku6C-3fe4A:
29.9		 5ku6C-3fe4A:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 GLN A 109
HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.74A 5ku6D-3fe4A:
29.8		 5ku6D-3fe4A:
32.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 7 GLN A 109
HIS A 111
VAL A 140
LEU A 219
THR A 220
 None
MG  A 901 (-3.4A)
None
None
None
 0.87A 5m78A-3fe4A:
31.1		 5m78A-3fe4A:
17.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 111
HIS A 138
VAL A 161
LEU A 219
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.71A 5ogjA-3fe4A:
30.8		 5ogjA-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
 0.70A 5ogjA-3fe4A:
30.8		 5ogjA-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 111
HIS A 138
VAL A 161
LEU A 219
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.69A 5ogjB-3fe4A:
30.2		 5ogjB-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
 0.70A 5ogjB-3fe4A:
30.2		 5ogjB-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 5 HIS A 111
HIS A 138
VAL A 161
LEU A 219
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
 0.67A 5ohhA-3fe4A:
30.3		 5ohhA-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		4 / 5 HIS A 138
VAL A 161
LEU A 219
THR A 220
 MG  A 901 (-3.2A)
None
None
None
 0.75A 5ohhA-3fe4A:
30.3		 5ohhA-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 111
HIS A 138
VAL A 161
LEU A 219
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
 0.68A 5ohhB-3fe4A:
30.9		 5ohhB-3fe4A:
34.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 6 HIS A 138
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
 0.70A 5ohhB-3fe4A:
30.9		 5ohhB-3fe4A:
34.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.72A 5tt3A-3fe4A:
22.8		 5tt3A-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.2A)
None
None
None
None
None
None
 0.81A 5tt3A-3fe4A:
22.8		 5tt3A-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.78A 5tt3B-3fe4A:
22.0		 5tt3B-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.72A 5tt3C-3fe4A:
22.9		 5tt3C-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.57A 5tt3C-3fe4A:
22.9		 5tt3C-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.77A 5tt3C-3fe4A:
22.9		 5tt3C-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 10 HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 5tt3C-3fe4A:
22.9		 5tt3C-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.70A 5tt3E-3fe4A:
22.8		 5tt3E-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.81A 5tt3F-3fe4A:
22.5		 5tt3F-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.71A 5tt3F-3fe4A:
22.5		 5tt3F-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 9 HIS A 111
HIS A 113
HIS A 138
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
None
 0.71A 5tt3G-3fe4A:
22.1		 5tt3G-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 8 HIS A 111
HIS A 113
HIS A 138
VAL A 140
LEU A 219
THR A 220
TRP A 230
 MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
MG  A 901 (-3.2A)
None
None
None
None
 0.72A 5tt3H-3fe4A:
22.5		 5tt3H-3fe4A:
28.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 THR A 220
GLU A 125
HIS A 111
 None
MG  A 901 ( 4.4A)
MG  A 901 (-3.4A)
 0.88A 5xioA-3fe4A:
undetectable		 5xioA-3fe4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 GLU A 125
TRP A 230
HIS A 111
 MG  A 901 ( 4.4A)
None
MG  A 901 (-3.4A)
 0.87A 5xipA-3fe4A:
undetectable		 5xipA-3fe4A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 GLU A 136
TRP A 230
HIS A 111
 None
None
MG  A 901 (-3.4A)
 0.95A 5xipA-3fe4A:
undetectable		 5xipA-3fe4A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 THR A 220
GLU A 125
HIS A 111
 None
MG  A 901 ( 4.4A)
MG  A 901 (-3.4A)
 0.83A 5xiqB-3fe4A:
undetectable		 5xiqB-3fe4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 THR A 220
GLU A 125
HIS A 111
 None
MG  A 901 ( 4.4A)
MG  A 901 (-3.4A)
 0.84A 5xiqD-3fe4A:
undetectable		 5xiqD-3fe4A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		3 / 3 VAL A 232
TYR A 213
GLU A 136
 None
 0.95A 5zmqD-3fe4A:
undetectable
5zmqE-3fe4A:
undetectable		 5zmqD-3fe4A:
21.22
5zmqE-3fe4A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 ASN A  83
HIS A  85
GLN A 109
HIS A 111
HIS A 113
LEU A 219
THR A 220
TRP A 230
 None
None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
 0.70A 6bbsA-3fe4A:
27.9		 6bbsA-3fe4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 ASN A  83
GLN A 109
HIS A 111
HIS A 113
VAL A 140
LEU A 219
THR A 220
TRP A 230
 None
None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
 0.69A 6bc9A-3fe4A:
31.6		 6bc9A-3fe4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 5 HIS A  85
GLU A 125
HIS A 138
LEU A 159
VAL A 161
 None
MG  A 901 ( 4.4A)
MG  A 901 (-3.2A)
None
None
 0.61A 6bc9A-3fe4A:
31.6		 6bc9A-3fe4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		8 / 12 GLN A 109
HIS A 111
HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
TRP A 230
 None
MG  A 901 (-3.4A)
MG  A 901 (-3.4A)
None
None
None
None
None
 0.64A 6bccA-3fe4A:
31.6		 6bccA-3fe4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		7 / 12 HIS A 113
VAL A 140
VAL A 161
LEU A 219
THR A 220
PRO A 223
TRP A 230
 MG  A 901 (-3.4A)
None
None
None
None
None
None
 0.75A 6bccA-3fe4A:
31.6		 6bccA-3fe4A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3fe4 CARBONIC ANHYDRASE 6
(Homo
sapiens) 		5 / 12 LEU A 219
THR A 220
THR A 221
PRO A 223
TRP A 230
 None
 0.48A 6bccA-3fe4A:
31.6		 6bccA-3fe4A:
16.36