SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3feo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 PRO A 116
PHE A 129
GLY A  82
TRP A  64
 None
 0.92A 2y7kA-3feoA:
undetectable		 2y7kA-3feoA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE A 209
LEU A 188
PHE A 200
LEU A 374
 None
 0.88A 3adxA-3feoA:
undetectable		 3adxA-3feoA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 CYH A 303
ALA A 243
VAL A 245
PHE A 285
LEU A 281
 None
 1.32A 3b0wB-3feoA:
undetectable		 3b0wB-3feoA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 399
LEU A 428
CYH A 381
ILE A 395
PHE A 397
 None
 1.26A 3mnoA-3feoA:
undetectable		 3mnoA-3feoA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 399
LEU A 428
CYH A 381
ILE A 395
PHE A 397
 None
 1.24A 3mnpA-3feoA:
undetectable		 3mnpA-3feoA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 184
GLY A 183
LEU A 208
PRO A 377
LEU A 374
 None
 1.05A 4fp9A-3feoA:
undetectable		 4fp9A-3feoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 184
GLY A 183
LEU A 208
PRO A 377
LEU A 374
 None
 1.05A 4fp9C-3feoA:
undetectable		 4fp9C-3feoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 184
GLY A 183
LEU A 208
PRO A 377
LEU A 374
 None
 1.05A 4fp9D-3feoA:
undetectable		 4fp9D-3feoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 184
GLY A 183
LEU A 208
PRO A 377
LEU A 374
 None
 1.05A 4fp9F-3feoA:
undetectable		 4fp9F-3feoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A 184
GLY A 183
LEU A 208
PRO A 377
LEU A 374
 None
 1.05A 4fzvA-3feoA:
undetectable		 4fzvA-3feoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ARG A 172
ASP A 300
ASP A 265
 None
 0.87A 4kicB-3feoA:
undetectable		 4kicB-3feoA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 7 LEU A 113
VAL A 114
PRO A 116
GLU A  50
 None
 0.98A 4lb2A-3feoA:
undetectable		 4lb2A-3feoA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 4 VAL A  28
ILE A  43
ASN A  94
VAL A 148
 None
 1.33A 5ajqA-3feoA:
undetectable		 5ajqA-3feoA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASN A  53
PRO A 116
GLN A 120
 None
 0.58A 6jnhA-3feoA:
undetectable		 6jnhA-3feoA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3feo MBT
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASN A  53
PRO A 116
GLN A 120
 None
 0.59A 6jogA-3feoA:
undetectable		 6jogA-3feoA:
17.21