SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3feu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)
3feu PUTATIVE LIPOPROTEIN
(Aliivibrio
fischeri)
5 / 12 LEU A  41
ILE A 163
SER A 145
PHE A 153
ILE A  52
None
1.36A 1xotA-3feuA:
undetectable
1xotA-3feuA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)
3feu PUTATIVE LIPOPROTEIN
(Aliivibrio
fischeri)
5 / 11 ASN A 160
GLY A 165
THR A 175
ILE A 172
THR A 152
None
1.26A 2f9wA-3feuA:
undetectable
2f9wB-3feuA:
undetectable
2f9wA-3feuA:
21.25
2f9wB-3feuA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)
3feu PUTATIVE LIPOPROTEIN
(Aliivibrio
fischeri)
5 / 12 THR A  24
VAL A  26
VAL A 150
SER A 145
TYR A  71
None
1.33A 3d4sA-3feuA:
undetectable
3d4sA-3feuA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)
3feu PUTATIVE LIPOPROTEIN
(Aliivibrio
fischeri)
4 / 6 GLN A  76
PHE A  85
PRO A  81
LEU A  89
None
1.38A 3tgvD-3feuA:
undetectable
3tgvD-3feuA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)
3feu PUTATIVE LIPOPROTEIN
(Aliivibrio
fischeri)
3 / 3 TYR A  70
HIS A  56
PHE A  27
None
0.97A 6esmA-3feuA:
undetectable
6esmA-3feuA:
20.11