SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3fez'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		5 / 12 TYR A 157
LEU A  29
THR A 106
TYR A  53
ILE A   6
 None
 1.09A 1mx8A-3fezA:
undetectable		 1mx8A-3fezA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		5 / 12 LEU A  36
PHE A 119
SER A  58
PHE A  70
ILE A   6
 None
 1.27A 1xosA-3fezA:
undetectable		 1xosA-3fezA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		4 / 8 TYR A 157
ASP A 155
TYR A  72
TYR A  53
 None
 1.03A 2bteA-3fezA:
undetectable		 2bteA-3fezA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		4 / 7 TYR A 157
ASP A 155
TYR A  72
TYR A  53
 None
 1.08A 2bytA-3fezA:
undetectable		 2bytA-3fezA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		4 / 7 TYR A 157
ASP A 155
TYR A  72
TYR A  53
 None
 1.08A 2bytD-3fezA:
undetectable		 2bytD-3fezA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		4 / 7 TYR A  38
VAL A   4
ILE A 117
THR A   8
 None
 1.08A 3tneB-3fezA:
undetectable		 3tneB-3fezA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3fez UNCHARACTERIZED
FERREDOXIN FOLD
PROTEIN RELATED TO
ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASES
(Listeria
monocytogenes) 		4 / 8 ASN A  20
THR A   7
GLN A  48
GLY A  50
 None
 0.96A 5nzxA-3fezA:
undetectable		 5nzxA-3fezA:
20.93