SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ff0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O7G_A_ASCA303_0 (PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2)	3ff0	PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2 (Pseudomonas aeruginosa)	4 / 7	PHE A 121 HIS A 123 TYR A 27 ARG A 38	GOL A 166 (-4.5A) None GOL A 167 (-4.8A) GOL A 167 ( 4.6A)	1.37A	4o7gA-3ff0A: undetectable 4o7gB-3ff0A: undetectable	4o7gA-3ff0A: 19.70 4o7gB-3ff0A: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KF8_A_GCSA404_1 (PREDICTED ACETYLTRANSFERASE)	3ff0	PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2 (Pseudomonas aeruginosa)	4 / 8	GLU A 114 PRO A 79 GLY A 105 ASP A 80	None	0.91A	5kf8A-3ff0A: undetectable	5kf8A-3ff0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_A_GCSA407_1 (PREDICTED ACETYLTRANSFERASE)	3ff0	PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2 (Pseudomonas aeruginosa)	4 / 8	GLU A 114 PRO A 79 GLY A 105 ASP A 80	None	0.68A	5kgpA-3ff0A: undetectable	5kgpA-3ff0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KGP_B_GCSB405_1 (PREDICTED ACETYLTRANSFERASE)	3ff0	PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2 (Pseudomonas aeruginosa)	4 / 8	GLU A 114 PRO A 79 GLY A 105 ASP A 80	None	0.67A	5kgpB-3ff0A: undetectable	5kgpB-3ff0A: 21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MZJ_A_TEPA2401_1 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	3ff0	PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2 (Pseudomonas aeruginosa)	4 / 8	LEU A 50 MET A 139 ASN A 119 ILE A 107	UNL A 163 ( 4.0A) None None None	0.95A	5mzjA-3ff0A: undetectable	5mzjA-3ff0A: 15.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4O7G_A_ASCA303_0","PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2","3ff0","PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2","Pseudomonas aeruginosa",4,"PHE A 121;HIS A 123;TYR A  27;ARG A  38","GOL A 166 (-4.5A);None;GOL A 167 (-4.8A);GOL A 167 ( 4.6A)","1.37A","4o7gA-3ff0A:undetectable;4o7gB-3ff0A:undetectable","4o7gA-3ff0A:19.70;4o7gB-3ff0A:19.70"],["5KF8_A_GCSA404_1","PREDICTED ACETYLTRANSFERASE","3ff0","PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2","Pseudomonas aeruginosa",4,"GLU A 114;PRO A  79;GLY A 105;ASP A  80","None","0.91A","5kf8A-3ff0A:undetectable","5kf8A-3ff0A:21.66"],["5KGP_A_GCSA407_1","PREDICTED ACETYLTRANSFERASE","3ff0","PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2","Pseudomonas aeruginosa",4,"GLU A 114;PRO A  79;GLY A 105;ASP A  80","None","0.68A","5kgpA-3ff0A:undetectable","5kgpA-3ff0A:21.66"],["5KGP_B_GCSB405_1","PREDICTED ACETYLTRANSFERASE","3ff0","PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2","Pseudomonas aeruginosa",4,"GLU A 114;PRO A  79;GLY A 105;ASP A  80","None","0.67A","5kgpB-3ff0A:undetectable","5kgpB-3ff0A:21.66"],["5MZJ_A_TEPA2401_1","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","3ff0","PHENAZINE BIOSYNTHESIS PROTEIN PHZB 2","Pseudomonas aeruginosa",4,"LEU A  50;MET A 139;ASN A 119;ILE A 107","UNL A 163 ( 4.0A);None;None;None","0.95A","5mzjA-3ff0A:undetectable","5mzjA-3ff0A:15.89"]]