SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ff2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		4 / 6 PHE A 114
ASN A  34
ARG A  83
ASN A  61
 None
None
ACT  A 117 (-3.0A)
ACT  A 117 ( 4.8A)
 1.31A 1t9uA-3ff2A:
undetectable		 1t9uA-3ff2A:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.80A 2nmzA-3ff2A:
undetectable		 2nmzA-3ff2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.77A 2nnkA-3ff2A:
undetectable		 2nnkA-3ff2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		5 / 10 TYR A  25
ALA A  13
ALA A   9
ALA A  12
TYR A  22
 None
 1.37A 2r2vC-3ff2A:
undetectable
2r2vF-3ff2A:
undetectable
2r2vG-3ff2A:
undetectable		 2r2vC-3ff2A:
13.79
2r2vF-3ff2A:
13.79
2r2vG-3ff2A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.77A 3k4vA-3ff2A:
undetectable		 3k4vA-3ff2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.82A 3nduD-3ff2A:
undetectable		 3nduD-3ff2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.82A 3pwrA-3ff2A:
undetectable		 3pwrA-3ff2A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		3 / 3 ARG A 111
VAL A  23
THR A  47
 None
 0.80A 3tl9A-3ff2A:
undetectable		 3tl9A-3ff2A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 3ff2 UNCHARACTERIZED
CYSTATIN FOLD
PROTEIN
(YP_497570.1) FROM
NTF2 SUPERFAMILY
(Novosphingobium
aromaticivorans) 		4 / 6 GLU A  32
THR A  21
TYR A  22
PHE A 114
 None
 1.34A 5lrbA-3ff2A:
undetectable		 5lrbA-3ff2A:
8.85