SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ff4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 5 TYR A  62
LEU A  94
THR A  58
ARG A  82
 None
 1.23A 1i2wA-3ff4A:
undetectable		 1i2wA-3ff4A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 ARG A  82
ASN A  -1
HIS A  29
PHE A 119
 None
 1.22A 1tdnA-3ff4A:
3.1		 1tdnA-3ff4A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 5 VAL A  41
ILE A  32
MET A   1
ARG A  15
 None
 1.43A 3pyyB-3ff4A:
undetectable		 3pyyB-3ff4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 VAL A  56
LEU A  78
TYR A  74
LEU A  61
 None
 0.94A 3qeoB-3ff4A:
undetectable		 3qeoB-3ff4A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 5 ILE A  46
PRO A  11
LYS A  38
GLY A  39
 None
 1.17A 3tkdA-3ff4A:
2.0		 3tkdA-3ff4A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 7 ILE A  97
ILE A 103
SER A  70
LEU A  61
 None
 0.88A 3ua5B-3ff4A:
undetectable		 3ua5B-3ff4A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3ff4 UNCHARACTERIZED
PROTEIN
(Cytophaga
hutchinsonii) 		4 / 4 THR A 110
LEU A 114
HIS A  29
GLY A 117
 None
 1.13A 5gwyA-3ff4A:
undetectable		 5gwyA-3ff4A:
20.39