SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ffc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ffc CF34 ALPHA CHAIN
(Homo
sapiens) 		4 / 6 TYR D  32
TYR D  25
GLY D  57
ASP D  60
 None
 1.24A 2g72A-3ffcD:
undetectable		 2g72A-3ffcD:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ffc CF34 ALPHA CHAIN
(Homo
sapiens) 		4 / 7 ARG D  71
PRO D  45
SER D  47
GLY D  93
 None
 1.08A 3hcnA-3ffcD:
undetectable		 3hcnA-3ffcD:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3ffc CF34 ALPHA CHAIN
(Homo
sapiens) 		4 / 4 GLY D  93
LEU D  92
VAL D 120
GLU D  15
 None
 1.45A 5yw0A-3ffcD:
undetectable		 5yw0A-3ffcD:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3ffc CF34 ALPHA CHAIN
(Homo
sapiens) 		3 / 3 ASP D 173
LEU D  92
ARG D  71
 None
 0.70A 7dfrA-3ffcD:
undetectable		 7dfrA-3ffcD:
20.67