SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ffr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 VAL A 200
LEU A 194
LEU A  54
LEU A  51
 None
 0.76A 1cqpA-3ffrA:
3.4
1cqpB-3ffrA:
3.3		 1cqpA-3ffrA:
19.89
1cqpB-3ffrA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 12 GLU A 111
PRO A 127
ASP A 129
ALA A 130
ILE A 133
 None
 1.40A 1s14B-3ffrA:
undetectable		 1s14B-3ffrA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 6 THR A  17
VAL A  18
LEU A  14
ALA A 343
 None
 1.04A 2e1qA-3ffrA:
undetectable		 2e1qA-3ffrA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 6 THR A  17
VAL A  18
LEU A  14
ALA A 343
 None
 1.01A 2e1qC-3ffrA:
undetectable		 2e1qC-3ffrA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 8 MET A 146
LEU A 135
ARG A 155
PRO A 174
SER A 170
 None
 1.31A 2qd2A-3ffrA:
undetectable		 2qd2A-3ffrA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 8 THR A  17
VAL A  18
LEU A  14
ALA A 343
 None
 1.02A 3ax7A-3ffrA:
undetectable		 3ax7A-3ffrA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		3 / 3 THR A 136
SER A  94
PHE A  86
 None
 0.68A 3d4sA-3ffrA:
undetectable		 3d4sA-3ffrA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 9 MET A 146
LEU A 135
ARG A 155
PRO A 174
SER A 170
 None
 1.36A 3hcnB-3ffrA:
2.5		 3hcnB-3ffrA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 10 MET A 146
LEU A 135
ARG A 155
PRO A 174
SER A 170
 None
 1.37A 3hcoB-3ffrA:
undetectable		 3hcoB-3ffrA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 6 LEU A 203
ASN A  79
SER A 183
PHE A 185
 None
 1.41A 3i9jB-3ffrA:
undetectable		 3i9jB-3ffrA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 11 ILE A 281
ILE A 313
PHE A 287
VAL A 324
GLY A 325
 None
 0.89A 3kw4A-3ffrA:
undetectable		 3kw4A-3ffrA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 4 SER A  94
SER A 142
THR A 140
SER A 141
 None
None
LLP  A 190 ( 2.9A)
None
 1.38A 3loqA-3ffrA:
3.9		 3loqA-3ffrA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 316
PHE A 287
ALA A 323
THR A   8
ALA A 326
 P33  A 368 ( 4.6A)
None
None
None
None
 0.91A 3ua1A-3ffrA:
undetectable		 3ua1A-3ffrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 THR A  17
VAL A  18
LEU A  14
ALA A 343
 None
 0.95A 3uniA-3ffrA:
undetectable		 3uniA-3ffrA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 8 THR A  17
VAL A  18
LEU A  14
ALA A 343
 None
 0.95A 3uniB-3ffrA:
undetectable		 3uniB-3ffrA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 135
ARG A 155
PRO A 174
SER A 170
 None
 1.20A 4klrA-3ffrA:
2.4		 4klrA-3ffrA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		7 / 12 ILE A 202
VAL A 200
ILE A 248
GLY A 252
ALA A  47
LEU A  55
LEU A  57
 None
 1.22A 4o1zA-3ffrA:
undetectable		 4o1zA-3ffrA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 8 ILE A 124
ARG A 155
ILE A 133
MET A 146
 None
 0.99A 4xtaB-3ffrA:
undetectable		 4xtaB-3ffrA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 SER A  94
ARG A 337
SER A 141
GLU A 139
 None
 1.31A 4xzkA-3ffrA:
undetectable		 4xzkA-3ffrA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 6 LYS A 175
PRO A 174
LEU A  54
GLU A  56
 None
 1.35A 4z4cA-3ffrA:
2.2		 4z4cA-3ffrA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 171
PRO A 174
LEU A  55
GLU A  56
 None
 1.02A 4z4fA-3ffrA:
undetectable		 4z4fA-3ffrA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		3 / 3 ALA A  47
ASN A  50
LEU A  51
 None
 0.45A 5i1nC-3ffrA:
undetectable		 5i1nC-3ffrA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		4 / 7 LEU A 171
PRO A 174
LEU A  55
GLU A  56
 None
 0.95A 5t7bA-3ffrA:
2.3		 5t7bA-3ffrA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 12 ILE A 316
PHE A 287
ALA A 323
THR A   8
ALA A 326
 P33  A 368 ( 4.6A)
None
None
None
None
 0.92A 5vcgA-3ffrA:
undetectable		 5vcgA-3ffrA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3ffr PHOSPHOSERINE
AMINOTRANSFERASE
SERC
(Cytophaga
hutchinsonii) 		5 / 12 GLY A 193
GLY A  10
GLU A  13
ASP A 257
VAL A 254
 LLP  A 190 ( 3.6A)
LLP  A 190 ( 3.9A)
None
None
None
 0.97A 5wz1A-3ffrA:
3.3		 5wz1A-3ffrA:
19.51